Lineage for Family c.56.2.1: Purine and uridine phosphorylases

  1. Root: SCOP 1.67
  2. 383641Class c: Alpha and beta proteins (a/b) [51349] (130 folds)
  3. 398073Fold c.56: Phosphorylase/hydrolase-like [53162] (6 superfamilies)
    core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops
  4. 398089Superfamily c.56.2: Purine and uridine phosphorylases [53167] (1 family) (S)
    complex architecture; contains mixed beta-sheet of 8 strands, order 23415867, strands 3, 6 & 7 are antiparallel to the rest; and barrel, closed; n=5, S=8
  5. 398090Family c.56.2.1: Purine and uridine phosphorylases [53168] (5 proteins)

Proteins:

  1. 3980915'-deoxy-5'-methylthioadenosine phosphorylase [53174] (2 species)
    1. 398092Species Archaeon Sulfolobus solfataricus [TaxId:2287] [69536] (9 PDB entries)
    2. 398129Species Human (Homo sapiens) [TaxId:9606] [53175] (3 PDB entries)
  2. 3981335'-Methylthioadenosine/S-Adenosylhomocysteine nucleosidase [82448] (1 species)
  3. 398141Purine nucleoside phosphorylase, PNP [53169] (7 species)
    1. 398142Species Cellulomonas sp. [TaxId:40001] [53173] (2 PDB entries)
    2. 398149Species Cow (Bos taurus) [TaxId:9913] [53171] (15 PDB entries)
    3. 398175Species Escherichia coli [TaxId:562] [53172] (19 PDB entries)
    4. 398239Species Human (Homo sapiens) [TaxId:9606] [53170] (7 PDB entries)
    5. 398247Species Mycobacterium tuberculosis [TaxId:1773] [64098] (3 PDB entries)
    6. 398257Species Thermus thermophilus [TaxId:274] [89721] (4 PDB entries)
    7. 398282Species Vibrio cholerae [TaxId:666] [102499] (2 PDB entries)
  4. 398295Putative uridine phosphorylase [102500] (1 species)
  5. 398310Uridine phosphorylase [53176] (1 species)
    • 398311Species Escherichia coli [TaxId:562] [53177] (6 PDB entries)
      also includes the PDB entry (1rxs) where protein chains are designated by both upper case and lower case letters creating problems with its processing and presentation in SCOP

More info for Family c.56.2.1: Purine and uridine phosphorylases

Timeline for Family c.56.2.1: Purine and uridine phosphorylases: