Lineage for Family c.56.2.1: Purine and uridine phosphorylases

  1. Root: SCOP 1.65
  2. 305035Class c: Alpha and beta proteins (a/b) [51349] (121 folds)
  3. 317273Fold c.56: Phosphorylase/hydrolase-like [53162] (6 superfamilies)
    core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops
  4. 317289Superfamily c.56.2: Purine and uridine phosphorylases [53167] (1 family) (S)
    complex architecture; contains mixed beta-sheet of 8 strands, order 23415867, strands 3, 6 & 7 are antiparallel to the rest; and barrel, closed; n=5, S=8
  5. 317290Family c.56.2.1: Purine and uridine phosphorylases [53168] (4 proteins)

Proteins:

  1. 3172915'-deoxy-5'-methylthioadenosine phosphorylase [53174] (2 species)
    1. 317292Species Archaeon Sulfolobus solfataricus [TaxId:2287] [69536] (9 PDB entries)
    2. 317329Species Human (Homo sapiens) [TaxId:9606] [53175] (2 PDB entries)
  2. 3173325'-Methylthioadenosine/S-Adenosylhomocysteine nucleosidase [82448] (1 species)
  3. 317338Purine nucleoside phosphorylase, PNP [53169] (6 species)
    1. 317339Species Cellulomonas sp. [TaxId:40001] [53173] (2 PDB entries)
    2. 317346Species Cow (Bos taurus) [TaxId:9913] [53171] (13 PDB entries)
    3. 317360Species Escherichia coli [TaxId:562] [53172] (3 PDB entries)
    4. 317376Species Human (Homo sapiens) [TaxId:9606] [53170] (2 PDB entries)
    5. 317379Species Mycobacterium tuberculosis [TaxId:1773] [64098] (2 PDB entries)
    6. 317386Species Thermus thermophilus [TaxId:274] [89721] (4 PDB entries)
  4. 317411Uridine phosphorylase [53176] (1 species)

More info for Family c.56.2.1: Purine and uridine phosphorylases

Timeline for Family c.56.2.1: Purine and uridine phosphorylases: