Lineage for Protein: Retroviral integrase, catalytic domain

  1. Root: SCOPe 2.04
  2. 1565955Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1605035Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
    3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest
  4. 1606596Superfamily c.55.3: Ribonuclease H-like [53098] (15 families) (S)
    consists of one domain of this fold
  5. 1606866Family c.55.3.2: Retroviral integrase, catalytic domain [53107] (2 proteins)
  6. 1606867Protein Retroviral integrase, catalytic domain [53108] (3 species)

Species:

  1. 1606868Human immunodeficiency virus type 1 [TaxId:11676] [53110] (42 PDB entries)
    1. Domain for 1b92:
    2. Domain for 1b9d:
    3. Domain for 1b9f:
    4. Domain for 1bhl:
    5. Domains for 1bi4:
      1. 1606940Domain d1bi4a_: 1bi4 A: [33666]
      2. 1606941Domain d1bi4b_: 1bi4 B: [33667]
      3. 1606942Domain d1bi4c_: 1bi4 C: [33668]
    6. Domains for 1bis:
      1. 1606901Domain d1bisa_: 1bis A: [33650]
      2. 1606902Domain d1bisb_: 1bis B: [33651]
    7. Domains for 1biu:
      1. 1606930Domain d1biua_: 1biu A: [33663]
        protein/DNA complex; complexed with mg
      2. 1606931Domain d1biub_: 1biu B: [33664]
        protein/DNA complex; complexed with mg
      3. 1606932Domain d1biuc_: 1biu C: [33665]
        protein/DNA complex; complexed with mg
    8. Domains for 1biz:
      1. 1606903Domain d1biza_: 1biz A: [33652]
        complexed with cac
      2. 1606904Domain d1bizb_: 1biz B: [33653]
        complexed with cac
    9. Domains for 1bl3:
      1. 1606913Domain d1bl3a_: 1bl3 A: [33655]
        complexed with mg
      2. 1606914Domain d1bl3b_: 1bl3 B: [33656]
        complexed with mg
      3. 1606915Domain d1bl3c_: 1bl3 C: [33657]
        complexed with mg
    10. Domains for 1ex4:
      1. 1606944Domain d1ex4a2: 1ex4 A:56-222 [33670]
        Other proteins in same PDB: d1ex4a1, d1ex4b1
        complexed with cps
      2. 1606945Domain d1ex4b2: 1ex4 B:55-222 [33671]
        Other proteins in same PDB: d1ex4a1, d1ex4b1
        complexed with cps
    11. Domains for 1exq:
      1. 1606879Domain d1exqa_: 1exq A: [33646]
        complexed with cd, cl, so4
      2. 1606880Domain d1exqb_: 1exq B: [33647]
        complexed with cd, cl, so4
    12. Domain for 1hyv:
      • 1606881Domain d1hyva_: 1hyv A: [61424]
        protein/DNA complex; complexed with cl, so4, tta
    13. Domain for 1hyz:
      • 1606934Domain d1hyza_: 1hyz A: [61426]
        protein/DNA complex; complexed with cl, so4, tto
    14. Domain for 1itg:
    15. Domains for 1k6y:
      1. 1606935Domain d1k6ya2: 1k6y A:56-210 [68240]
        Other proteins in same PDB: d1k6ya1, d1k6yb1, d1k6yc1, d1k6yd1
        complexed with k, po4, zn
      2. 1606936Domain d1k6yb2: 1k6y B:56-212 [68242]
        Other proteins in same PDB: d1k6ya1, d1k6yb1, d1k6yc1, d1k6yd1
        complexed with k, po4, zn
      3. 1606937Domain d1k6yc2: 1k6y C:56-209 [68244]
        Other proteins in same PDB: d1k6ya1, d1k6yb1, d1k6yc1, d1k6yd1
        complexed with k, po4, zn
      4. 1606938Domain d1k6yd2: 1k6y D:56-211 [68246]
        Other proteins in same PDB: d1k6ya1, d1k6yb1, d1k6yc1, d1k6yd1
        complexed with k, po4, zn
    16. Domains for 1qs4:
      1. 1606918Domain d1qs4a_: 1qs4 A: [33658]
        protein/DNA complex; complexed with 100, mg
      2. 1606919Domain d1qs4b_: 1qs4 B: [33659]
        protein/DNA complex; complexed with 100, mg
      3. 1606920Domain d1qs4c_: 1qs4 C: [33660]
        protein/DNA complex; complexed with 100, mg
    17. Domains for 2b4j:
      1. 1606889Domain d2b4ja_: 2b4j A: [127833]
        Other proteins in same PDB: d2b4jc1, d2b4jd_
        automated match to d1bi4c_
        complexed with gol, po4
      2. 1606890Domain d2b4jb_: 2b4j B: [127834]
        Other proteins in same PDB: d2b4jc1, d2b4jd_
        automated match to d1bi4c_
        complexed with gol, po4
    18. Domain for 2itg:
    19. Domains for 3ao1:
      1. 1606891Domain d3ao1a_: 3ao1 A: [172279]
        automated match to d1bi4c_
        protein/DNA complex; complexed with bzx, cd, so4
      2. 1606892Domain d3ao1b_: 3ao1 B: [172280]
        automated match to d1bi4c_
        protein/DNA complex; complexed with bzx, cd, so4
    20. Domains for 3l3u:
      1. 1606869Domain d3l3ua_: 3l3u A: [236775]
        automated match to d3ao1a_
        complexed with so4
      2. 1606870Domain d3l3ub_: 3l3u B: [236773]
        automated match to d3ovnb_
        complexed with so4
    21. Domains for 3l3v:
      1. 1606922Domain d3l3va_: 3l3v A: [236772]
        automated match to d3ao1b_
        protein/DNA complex; complexed with cd, so4, suc
      2. 1606923Domain d3l3vb_: 3l3v B: [236774]
        automated match to d3ovnb_
        protein/DNA complex; complexed with cd, so4, suc
    22. Domains for 3ovn:
      1. 1606905Domain d3ovna_: 3ovn A: [183318]
        automated match to d1bi4c_
        protein/DNA complex; complexed with cd, mpv, so4, suc
      2. 1606906Domain d3ovnb_: 3ovn B: [183319]
        automated match to d1bi4c_
        protein/DNA complex; complexed with cd, mpv, so4, suc
    23. Domains for 3vq4:
      1. 1606897Domain d3vq4a_: 3vq4 A: [218019]
        automated match to d2itga_
        protein/DNA complex; complexed with 0nx, cd, so4
      2. 1606898Domain d3vq4b_: 3vq4 B: [218020]
        automated match to d2itga_
        protein/DNA complex; complexed with 0nx, cd, so4
    24. Domains for 3vq5:
      1. 1606873Domain d3vq5a_: 3vq5 A: [218021]
        automated match to d1bizb_
        protein/DNA complex; complexed with cd, cl, mmj, so4
      2. 1606874Domain d3vq5b_: 3vq5 B: [218022]
        automated match to d1bizb_
        protein/DNA complex; complexed with cd, cl, mmj, so4
    25. Domains for 3vq6:
      1. 1606887Domain d3vq6a_: 3vq6 A: [218023]
        automated match to d2itga_
        protein/DNA complex; protein/RNA complex; complexed with bck, cd, so4
      2. 1606888Domain d3vq6b_: 3vq6 B: [218024]
        automated match to d2itga_
        protein/DNA complex; protein/RNA complex; complexed with bck, cd, so4
    26. Domains for 3vq7:
      1. 1606871Domain d3vq7a_: 3vq7 A: [218025]
        automated match to d2itga_
        protein/DNA complex; complexed with cd, snu, so4, suc
      2. 1606872Domain d3vq7b_: 3vq7 B: [218026]
        automated match to d2itga_
        protein/DNA complex; complexed with cd, snu, so4, suc
    27. Domains for 3vq8:
      1. 1606877Domain d3vq8a_: 3vq8 A: [218027]
        automated match to d1bizb_
        protein/DNA complex; complexed with bcu, cd, cl, so4
      2. 1606878Domain d3vq8b_: 3vq8 B: [218028]
        automated match to d1bizb_
        protein/DNA complex; complexed with bcu, cd, cl, so4
    28. Domains for 3vq9:
      1. 1606884Domain d3vq9a_: 3vq9 A: [193266]
        automated match to d1bl3c_
        protein/DNA complex; complexed with fbb
      2. 1606885Domain d3vq9b_: 3vq9 B: [193267]
        automated match to d1bl3c_
        protein/DNA complex; complexed with fbb
      3. 1606886Domain d3vq9c_: 3vq9 C: [201255]
        automated match to d3vq9b_
        protein/DNA complex; complexed with fbb
    29. Domains for 3vqa:
      1. 1606899Domain d3vqaa_: 3vqa A: [218029]
        automated match to d2itga_
        protein/DNA complex; protein/RNA complex; complexed with cd, mwp, so4, suc
      2. 1606900Domain d3vqab_: 3vqa B: [218030]
        automated match to d2itga_
        protein/DNA complex; protein/RNA complex; complexed with cd, mwp, so4, suc
    30. Domains for 3vqb:
      1. 1606916Domain d3vqba_: 3vqb A: [218031]
        automated match to d2itga_
        protein/DNA complex; complexed with cd, fbg, so4
      2. 1606917Domain d3vqbb_: 3vqb B: [218032]
        automated match to d2itga_
        protein/DNA complex; complexed with cd, fbg, so4
    31. Domains for 3vqc:
      1. 1606928Domain d3vqca_: 3vqc A: [218033]
        automated match to d2itga_
        protein/DNA complex; complexed with cd, mpk, so4
      2. 1606929Domain d3vqcb_: 3vqc B: [218034]
        automated match to d2itga_
        protein/DNA complex; complexed with cd, mpk, so4
    32. Domains for 3vqd:
      1. 1606907Domain d3vqda_: 3vqd A: [218035]
        automated match to d2itga_
        protein/DNA complex; complexed with cd, mok, so4
      2. 1606908Domain d3vqdb_: 3vqd B: [218036]
        automated match to d2itga_
        protein/DNA complex; complexed with cd, mok, so4
    33. Domains for 3vqe:
      1. 1606875Domain d3vqea_: 3vqe A: [218037]
        automated match to d1bizb_
        protein/DNA complex; protein/RNA complex; complexed with cd, cl, fmq, so4
      2. 1606876Domain d3vqeb_: 3vqe B: [218038]
        automated match to d1bizb_
        protein/DNA complex; protein/RNA complex; complexed with cd, cl, fmq, so4
    34. Domains for 3vqp:
      1. 1606909Domain d3vqpa_: 3vqp A: [218039]
        automated match to d2itga_
        protein/DNA complex; protein/RNA complex; complexed with cd, cl, dbj, so4
      2. 1606910Domain d3vqpb_: 3vqp B: [218040]
        automated match to d2itga_
        protein/DNA complex; protein/RNA complex; complexed with cd, cl, dbj, so4
    35. Domains for 3vqq:
      1. 1606895Domain d3vqqa_: 3vqq A: [218041]
        automated match to d2itga_
        protein/DNA complex; protein/RNA complex; complexed with bte, cd, so4, suc
      2. 1606896Domain d3vqqb_: 3vqq B: [218042]
        automated match to d2itga_
        protein/DNA complex; protein/RNA complex; complexed with bte, cd, so4, suc
    36. Domain for 4lh4:
    37. Domain for 4lh5:
    38. Domain for 4o0j:
    39. Domain for 4o55:
    40. Domain for 4o5b:
    41. Domains for 4ovl:
      1. 1606893Domain d4ovla_: 4ovl A: [237439]
        automated match to d4ah9a_
        complexed with 1td, acy, edo, gol, so4
      2. 1606894Domain d4ovlb_: 4ovl B: [237438]
        automated match to d4ah9a_
        complexed with 1td, acy, edo, gol, so4
    42. Domain for 4tsx:
  2. 1606946Rous sarcoma virus RSV [TaxId:11886] [53109] (23 PDB entries)
    1. Domain for 1a5v:
    2. Domain for 1a5w:
    3. Domain for 1a5x:
    4. Domain for 1asu:
    5. Domain for 1asv:
    6. Domain for 1asw:
    7. Domains for 1c0m:
      1. 1606969Domain d1c0ma2: 1c0m A:49-216 [33640]
        Other proteins in same PDB: d1c0ma1, d1c0mb1, d1c0mc1, d1c0md1
      2. 1606970Domain d1c0mb2: 1c0m B:54-216 [33641]
        Other proteins in same PDB: d1c0ma1, d1c0mb1, d1c0mc1, d1c0md1
      3. 1606971Domain d1c0mc2: 1c0m C:49-216 [33642]
        Other proteins in same PDB: d1c0ma1, d1c0mb1, d1c0mc1, d1c0md1
      4. 1606972Domain d1c0md2: 1c0m D:54-216 [33643]
        Other proteins in same PDB: d1c0ma1, d1c0mb1, d1c0mc1, d1c0md1
    8. Domains for 1c1a:
      1. 1606973Domain d1c1aa2: 1c1a A:52-216 [33644]
        Other proteins in same PDB: d1c1aa1, d1c1ab1
      2. 1606974Domain d1c1ab2: 1c1a B:55-216 [33645]
        Other proteins in same PDB: d1c1aa1, d1c1ab1
    9. Domain for 1cxq:
    10. Domain for 1cxu:
    11. Domain for 1cz9:
    12. Domain for 1czb:
    13. Domain for 1vsd:
    14. Domain for 1vse:
    15. Domain for 1vsf:
    16. Domain for 1vsh:
    17. Domain for 1vsi:
    18. Domain for 1vsj:
    19. Domain for 1vsk:
    20. Domain for 1vsl:
    21. Domain for 1vsm:
    22. Domains for 3o4n:
      1. 1606955Domain d3o4na_: 3o4n A: [182791]
        automated match to d1asua_
        complexed with mes, zn
      2. 1606956Domain d3o4nb_: 3o4n B: [182792]
        automated match to d1asua_
        complexed with mes, zn
    23. Domain for 3o4q:
  3. 1606975Simian immunodeficiency virus [TaxId:11723] [53111] (1 PDB entry)

More info for Protein Retroviral integrase, catalytic domain from c.55.3.2: Retroviral integrase, catalytic domain

Timeline for Protein Retroviral integrase, catalytic domain from c.55.3.2: Retroviral integrase, catalytic domain: