SCOP 1.67: Protein: Mammalian type I hexokinase

Lineage for Protein: Mammalian type I hexokinase

Root: SCOP 1.67
Class c: Alpha and beta proteins (a/b) [51349] (130 folds)
Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest
Superfamily c.55.1: Actin-like ATPase domain [53067] (6 families)
duplication contains two domains of this fold
Family c.55.1.3: Hexokinase [53083] (3 proteins)
Protein Mammalian type I hexokinase [53086] (2 species)
further duplication: consists of two very similar lobes

Species:

Human (Homo sapiens) [TaxId:9606] [53087] (5 PDB entries)
1. Domains for 1cza:
  1. Domain d1czan1: 1cza N:16-222 [33463]
  2. Domain d1czan2: 1cza N:223-465 [33464]
  3. Domain d1czan3: 1cza N:466-670 [33465]
  4. Domain d1czan4: 1cza N:671-913 [33466]
    complexed with adp, g6p, glc; mutant
2. Domains for 1dgk:
  1. Domain d1dgkn1: 1dgk N:16-222 [33487]
  2. Domain d1dgkn2: 1dgk N:223-465 [33488]
  3. Domain d1dgkn3: 1dgk N:466-670 [33489]
  4. Domain d1dgkn4: 1dgk N:671-913 [33490]
    complexed with adp, glc, po4; mutant
3. Domains for 1hkb:
  1. Domain d1hkba1: 1hkb A:16-222 [33479]
  2. Domain d1hkba2: 1hkb A:223-465 [33480]
  3. Domain d1hkba3: 1hkb A:466-670 [33481]
  4. Domain d1hkba4: 1hkb A:671-914 [33482]
  5. Domain d1hkbb1: 1hkb B:16-222 [33483]
  6. Domain d1hkbb2: 1hkb B:223-465 [33484]
  7. Domain d1hkbb3: 1hkb B:466-670 [33485]
  8. Domain d1hkbb4: 1hkb B:671-914 [33486]
    complexed with ca, g6p, glc
4. Domains for 1hkc:
  1. Domain d1hkca1: 1hkc A:16-222 [33475]
  2. Domain d1hkca2: 1hkc A:223-465 [33476]
  3. Domain d1hkca3: 1hkc A:466-670 [33477]
  4. Domain d1hkca4: 1hkc A:671-914 [33478]
    complexed with glc, k, po4
5. Domains for 1qha:
  1. Domain d1qhaa1: 1qha A:12-222 [33467]
  2. Domain d1qhaa2: 1qha A:223-465 [33468]
  3. Domain d1qhaa3: 1qha A:466-670 [33469]
  4. Domain d1qhaa4: 1qha A:671-914 [33470]
  5. Domain d1qhab1: 1qha B:16-222 [33471]
  6. Domain d1qhab2: 1qha B:223-465 [33472]
  7. Domain d1qhab3: 1qha B:466-670 [33473]
  8. Domain d1qhab4: 1qha B:671-914 [33474]
Rat (Rattus norvegicus) [TaxId:10116] [53088] (1 PDB entry)
- Domains for 1bg3:
  1. Domain d1bg3a1: 1bg3 A:1-222 [33491]
  2. Domain d1bg3a2: 1bg3 A:223-465 [33492]
  3. Domain d1bg3a3: 1bg3 A:466-670 [33493]
  4. Domain d1bg3a4: 1bg3 A:671-911 [33494]
  5. Domain d1bg3b1: 1bg3 B:1-222 [33495]
  6. Domain d1bg3b2: 1bg3 B:223-465 [33496]
  7. Domain d1bg3b3: 1bg3 B:466-670 [33497]
  8. Domain d1bg3b4: 1bg3 B:671-911 [33498]
    complexed with ca, g6p, glc

More info for Protein Mammalian type I hexokinase from c.55.1.3: Hexokinase

Timeline for Protein Mammalian type I hexokinase from c.55.1.3: Hexokinase:

Protein Mammalian type I hexokinase from c.55.1.3: Hexokinase first appeared (with stable ids) in SCOP 1.55
Protein Mammalian type I hexokinase from c.55.1.3: Hexokinase appears in SCOP 1.65
Protein Mammalian type I hexokinase from c.55.1.3: Hexokinase appears in SCOP 1.69
Protein Mammalian type I hexokinase from c.55.1.3: Hexokinase appears in the current release, SCOPe 2.08