SCOP 1.65: Family c.55.1.3: Hexokinase

Lineage for Family c.55.1.3: Hexokinase

1. Root: SCOP 1.65

2. Class c: Alpha and beta proteins (a/b) [51349] (121 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.1: Actin-like ATPase domain [53067] (6 families)
   duplication contains two domains of this fold

5. Family c.55.1.3: Hexokinase [53083] (2 proteins)

Proteins:

1. Hexokinase [53084] (2 species)

   1. Species Baker's yeast (Saccharomyces cerevisiae), pII [TaxId:4932] [64092] (1 PDB entry)

   2. Species Blood fluke (Schistosoma mansoni) [TaxId:6183] [53085] (1 PDB entry)

2. Mammalian type I hexokinase [53086] (2 species)
   further duplication: consists of two very similar lobes

   1. Species Human (Homo sapiens) [TaxId:9606] [53087] (5 PDB entries)

   2. Species Rat (Rattus norvegicus) [TaxId:10116] [53088] (1 PDB entry)

More info for Family c.55.1.3: Hexokinase

Timeline for Family c.55.1.3: Hexokinase:

• Family c.55.1.3: Hexokinase first appeared (with stable ids) in SCOP 1.55
  
• Family c.55.1.3: Hexokinase appears in SCOP 1.63
  
• Family c.55.1.3: Hexokinase appears in SCOP 1.67
  
• Family c.55.1.3: Hexokinase appears in the current release, SCOPe 2.08