SCOP 1.73: Protein: Flap endonuclease-1 (Fen-1 nuclease)

Lineage for Protein: Flap endonuclease-1 (Fen-1 nuclease)

Root: SCOP 1.73
Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
Fold c.120: PIN domain-like [88722] (1 superfamily)
3 layers, a/b/a; core: parallel beta-sheet of 5 strands, order 32145
Superfamily c.120.1: PIN domain-like [88723] (2 families)

Family c.120.1.2: 5' to 3' exonuclease catalytic domain [53045] (4 proteins)
contains an alpha-helical arch and additional strand 6 antiparallel to the rest; strand order 321456; similarity to the resolvase-like fold

Protein Flap endonuclease-1 (Fen-1 nuclease) [53052] (5 species)

Species:

Archaeon Archaeoglobus fulgidus [TaxId:2234] [102272] (2 PDB entries)
1. Domains for 1rxv:
  1. Domain d1rxva2: 1rxv A:4-219 [98056]
    Other proteins in same PDB: d1rxva1, d1rxvb1
  2. Domain d1rxvb2: 1rxv B:4-219 [98058]
    Other proteins in same PDB: d1rxva1, d1rxvb1
2. Domain for 1rxw:
  - Domain d1rxwa2: 1rxw A:3-219 [98060]
    Other proteins in same PDB: d1rxwa1
Archaeon Methanococcus jannaschii [TaxId:2190] [53053] (2 PDB entries)
1. Domain for 1a76:
  - Domain d1a76a2: 1a76 A:2-208 [33361]
    Other proteins in same PDB: d1a76a1
    complexed with mn
2. Domain for 1a77:
  - Domain d1a77a2: 1a77 A:2-208 [33360]
    Other proteins in same PDB: d1a77a1
    complexed with mg
Archaeon Pyrococcus furiosus [TaxId:2261] [53055] (1 PDB entry)
- Domains for 1b43:
  1. Domain d1b43a2: 1b43 A:1-219 [33362]
    Other proteins in same PDB: d1b43a1, d1b43b1
  2. Domain d1b43b2: 1b43 B:1-219 [33363]
    Other proteins in same PDB: d1b43a1, d1b43b1
Archaeon Pyrococcus horikoshii [TaxId:53953] [82436] (1 PDB entry)
- Domains for 1mc8:
  1. Domain d1mc8a2: 1mc8 A:2-220 [78946]
    Other proteins in same PDB: d1mc8a1, d1mc8b1
  2. Domain d1mc8b2: 1mc8 B:2-220 [78948]
    Other proteins in same PDB: d1mc8a1, d1mc8b1
    mutant
Human (Homo sapiens) [TaxId:9606] [142118] (1 PDB entry)
- Domains for 1ul1:
  1. Domain d1ul1x2: 1ul1 X:2-217 [119691]
    Other proteins in same PDB: d1ul1a1, d1ul1a2, d1ul1b1, d1ul1b2, d1ul1c1, d1ul1c2, d1ul1x1, d1ul1y1, d1ul1z1
    complexed with mg
  2. Domain d1ul1y2: 1ul1 Y:2-217 [119693]
    Other proteins in same PDB: d1ul1a1, d1ul1a2, d1ul1b1, d1ul1b2, d1ul1c1, d1ul1c2, d1ul1x1, d1ul1y1, d1ul1z1
    automatically matched to 1UL1 X:2-217
    complexed with mg
  3. Domain d1ul1z2: 1ul1 Z:2-217 [119695]
    Other proteins in same PDB: d1ul1a1, d1ul1a2, d1ul1b1, d1ul1b2, d1ul1c1, d1ul1c2, d1ul1x1, d1ul1y1, d1ul1z1
    automatically matched to 1UL1 X:2-217
    complexed with mg

More info for Protein Flap endonuclease-1 (Fen-1 nuclease) from c.120.1.2: 5' to 3' exonuclease catalytic domain

Timeline for Protein Flap endonuclease-1 (Fen-1 nuclease) from c.120.1.2: 5' to 3' exonuclease catalytic domain:

Protein Flap endonuclease-1 (Fen-1 nuclease) from c.120.1.2: 5' to 3' exonuclease catalytic domain first appeared (with stable ids) in SCOP 1.55, called Protein Flap endonuclease-1 from c.53.1.2: 5' to 3' exonuclease
Protein Flap endonuclease-1 (Fen-1 nuclease) from c.120.1.2: 5' to 3' exonuclease catalytic domain appears in SCOP 1.71
Protein Flap endonuclease-1 (Fen-1 nuclease) from c.120.1.2: 5' to 3' exonuclease catalytic domain appears in SCOP 1.75
Protein Flap endonuclease-1 (Fen-1 nuclease) from c.120.1.2: 5' to 3' exonuclease catalytic domain appears in the current release, SCOPe 2.08