SCOPe 2.03: Family c.48.1.2: Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain

Lineage for Family c.48.1.2: Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.48: TK C-terminal domain-like [52921] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 13245, strand 1 is antiparallel to the rest

4. Superfamily c.48.1: TK C-terminal domain-like [52922] (4 families)

5. Family c.48.1.2: Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain [52926] (4 proteins)
   automatically mapped to Pfam PF02780

Proteins:

1. 2-oxoisovalerate dehydrogenase E1b, C-domain [52929] (1 species)

   • Species Pseudomonas putida [TaxId:303] [52930] (2 PDB entries)

2. Branched-chain alpha-keto acid dehydrogenase [52927] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [52928] (23 PDB entries)
      Uniprot P21953 52-392

   2. Species Thermus thermophilus [TaxId:274] [102468] (4 PDB entries)

3. E1-beta subunit of pyruvate dehydrogenase, C-domain [69521] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [89713] (5 PDB entries)

   2. Species Pyrobaculum aerophilum [TaxId:13773] [69522] (1 PDB entry)

4. Pyruvate dehydrogenase E1-beta, PdhB, C-terminal domain [117611] (1 species)

   • Species Bacillus stearothermophilus [TaxId:1422] [117612] (2 PDB entries)
     Uniprot P21874

More info for Family c.48.1.2: Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain

Timeline for Family c.48.1.2: Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain:

• Family c.48.1.2: Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain first appeared (with stable ids) in SCOP 1.55, called Family c.48.1.2: Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-domain
  
• Family c.48.1.2: Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain appears in SCOPe 2.02
  
• Family c.48.1.2: Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain appears in SCOPe 2.04
  
• Family c.48.1.2: Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain appears in the current release, SCOPe 2.08