Lineage for Family c.47.1.10: Glutathione peroxidase-like

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2455315Fold c.47: Thioredoxin fold [52832] (2 superfamilies)
    core: 3 layers, a/b/a; mixed beta-sheet of 4 strands, order 4312; strand 3 is antiparallel to the rest
  4. 2455316Superfamily c.47.1: Thioredoxin-like [52833] (24 families) (S)
  5. 2456544Family c.47.1.10: Glutathione peroxidase-like [52901] (29 protein domains)

Protein Domains:

  1. 24565451-Cys peroxiredoxin [52909] (3 species)
    1. 2456546Species Human (Homo sapiens) [TaxId:9606] [52910] (3 PDB entries)
    2. 2456561Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [142367] (2 PDB entries)
      Uniprot Q5MYR6 60-238
    3. 2456566Species Plasmodium yoelii yoelii [TaxId:73239] [117599] (2 PDB entries)
      Uniprot Q7RGR1
  2. 2456575Alkyl hydroperoxide reductase AhpC [69516] (5 species)
    1. 2456576Species Amphibacillus xylanus [TaxId:1449] [142369] (1 PDB entry)
      Uniprot O87200 2-167
    2. 2456578Species Mycobacterium tuberculosis [TaxId:1773] [142368] (1 PDB entry)
      Uniprot Q7BHK8 2-170
    3. 2456582Species Salmonella enterica [TaxId:90371] [229124] (8 PDB entries)
    4. 2456638Species Salmonella typhimurium [TaxId:90371] [69517] (6 PDB entries)
    5. 3047725Species Salmonella typhimurium [TaxId:99287] [347787] (1 PDB entry)
  3. 2456688Bacterioferritin comigratory protein [142377] (1 species)
  4. 2456708Glutathione peroxidase [52902] (2 species)
    contains many insertions in the common fold
    1. 2456709Species Cow (Bos taurus) [TaxId:9913] [52903] (1 PDB entry)
    2. 2456712Species Human (Homo sapiens) [TaxId:9606] [142365] (1 PDB entry)
      Uniprot P07203 12-195
  5. 2456715Lipoprotein DsbF [142375] (1 species)
  6. 2456718Membrane-anchored thioredoxin-like protein TlpA, soluble domain [64068] (1 species)
  7. 2456722N-terminal, Prx domain of Hybrid-Prx5 [89708] (1 species)
  8. 2456726Peptide methionine sulfoxide reductase MsrA/MsrB, N-terminal domain [142385] (2 species)
    1. 2456727Species Neisseria gonorrhoeae [TaxId:485] [187786] (1 PDB entry)
    2. 2456729Species Neisseria meningitidis serogroup A [TaxId:65699] [142386] (4 PDB entries)
      Uniprot Q9JWM8 33-175
  9. 2456734Peroxiredoxin [117601] (1 species)
  10. 2456747Peroxiredoxin 5 [64066] (1 species)
  11. 2456762Peroxiredoxin dot5 [142387] (1 species)
  12. 2456765Peroxiredoxin-3 (AOP-1, SP-22) [142391] (1 species)
  13. 2456779Phenol hydroxylase, C-terminal domain [52911] (1 species)
  14. 2456789Plant peroxiredoxin [142379] (1 species)
  15. 2456792Probable thiol peroxidase PsaD [89710] (1 species)
  16. 2456796Probable thiol-disulfide isomerase/thioredoxin TTHA0593 [142389] (1 species)
  17. 2456800Putative peroxiredoxin Rv2238c/MT2298 [142381] (1 species)
  18. 2456808Soluble secreted antigen MPT53 [102457] (1 species)
  19. 2456811Thiol peroxidase Tpx [102452] (4 species)
    1. 2456812Species Escherichia coli K-12 [TaxId:83333] [189089] (4 PDB entries)
    2. 2456822Species Escherichia coli [TaxId:562] [102453] (1 PDB entry)
    3. 2456825Species Haemophilus influenzae [TaxId:727] [102454] (1 PDB entry)
      HI0751
    4. 2456828Species Mycobacterium tuberculosis [TaxId:1773] [117600] (2 PDB entries)
      Uniprot P66952
  20. 2456832Thiol-disulfide oxidoreductase ResA [102455] (1 species)
  21. 2456852thiol:disulfide oxidoreductase YkuV [142373] (1 species)
  22. 2456855Thioredoxin peroxidase 2 (thioredoxin peroxidase B, 2-cys peroxiredoxin) [52906] (3 species)
    1. 2456856Species Human (Homo sapiens) [TaxId:9606] [52908] (2 PDB entries)
    2. 2456873Species Norway rat (Rattus norvegicus) [TaxId:10116] [52907] (1 PDB entry)
      heme-binding protein 23, HBP23
    3. 2456876Species Plasmodium yoelii [TaxId:5861] [142366] (1 PDB entry)
      Uniprot Q86SB2 8-177
  23. 2456878Thioredoxin reductase TsaA [142383] (1 species)
  24. 2456881Thioredoxin-like protein CcmG (CycY, DsbE) [75237] (2 species)
    1. 2456882Species Bradyrhizobium japonicum [TaxId:375] [75238] (1 PDB entry)
    2. 2456884Species Escherichia coli [TaxId:562] [142370] (1 PDB entry)
      Uniprot P0AA86 49-184
  25. 2456886Thioredoxin-like protein Sco1 (YpmQ), soluble domain [102459] (3 species)
    1. 2456887Species Bacillus subtilis [TaxId:1423] [102460] (2 PDB entries)
    2. 2456891Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [142372] (2 PDB entries)
      Uniprot P23833 111-262
    3. 2456900Species Human (Homo sapiens) [TaxId:9606] [142371] (2 PDB entries)
      Uniprot O75880 138-297
  26. 2456904Tryparedoxin I [52904] (2 species)
    1. 2456905Species Crithidia fasciculata [TaxId:5656] [52905] (8 PDB entries)
    2. 2456914Species Trypanosoma brucei brucei [TaxId:5702] [89707] (1 PDB entry)
  27. 2456916Tryparedoxin II [64062] (1 species)
  28. 2456929Tryparedoxin peroxidase (thioredoxin peroxidase homologue) [64064] (2 species)
    1. 2456930Species Crithidia fasciculata [TaxId:5656] [64065] (1 PDB entry)
    2. 2456941Species Trypanosoma cruzi [TaxId:5693] [117598] (1 PDB entry)
      Uniprot O96763
  29. 2456952automated matches [190100] (19 species)
    not a true protein
    1. 2456953Species Aeropyrum pernix [311183] (1 PDB entry)
    2. 2456963Species Aeropyrum pernix [TaxId:272557] [186846] (9 PDB entries)
    3. 2457043Species Aeropyrum pernix [TaxId:56636] [187260] (1 PDB entry)
    4. 2457054Species Amphibacillus xylanus [TaxId:1449] [186822] (1 PDB entry)
    5. 2457064Species Ancylostoma ceylanicum [TaxId:53326] [197299] (2 PDB entries)
    6. 2457080Species Arenicola marina [TaxId:6344] [188412] (4 PDB entries)
    7. 2457101Species Bacillus subtilis [TaxId:1423] [188552] (3 PDB entries)
    8. 2457106Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [226432] (2 PDB entries)
    9. 2457118Species Bradyrhizobium diazoefficiens [TaxId:224911] [260055] (2 PDB entries)
    10. 2457125Species Burkholderia cenocepacia [TaxId:216591] [196688] (1 PDB entry)
    11. 2457128Species Escherichia coli [TaxId:562] [187437] (4 PDB entries)
    12. 2457134Species Escherichia coli [TaxId:83333] [267844] (1 PDB entry)
    13. 2457136Species Human (Homo sapiens) [TaxId:9606] [187259] (20 PDB entries)
    14. 2457221Species Larimichthys crocea [TaxId:215358] [256043] (1 PDB entry)
    15. 2457227Species Leishmania braziliensis [TaxId:5660] [256848] (2 PDB entries)
    16. 2457238Species Leishmania major [TaxId:5664] [226407] (3 PDB entries)
    17. 2457246Species Norway rat (Rattus norvegicus) [TaxId:10116] [225384] (1 PDB entry)
    18. 2457257Species Trypanosoma cruzi [TaxId:5693] [311182] (1 PDB entry)
    19. 3058681Species Arabidopsis thaliana [TaxId:3702] [358743] (1 PDB entry)

More info for Family c.47.1.10: Glutathione peroxidase-like

Timeline for Family c.47.1.10: Glutathione peroxidase-like: