SCOPe 2.06: Protein: Protein disulfide isomerase, PDI

Lineage for Protein: Protein disulfide isomerase, PDI

Root: SCOPe 2.06
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
Fold c.47: Thioredoxin fold [52832] (2 superfamilies)
core: 3 layers, a/b/a; mixed beta-sheet of 4 strands, order 4312; strand 3 is antiparallel to the rest
Superfamily c.47.1: Thioredoxin-like [52833] (24 families)
Family c.47.1.2: PDI-like [52849] (3 proteins)
duplication: contains two tandem repeats of this fold
Protein Protein disulfide isomerase, PDI [52850] (5 species)

Species:

Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [142358] (1 PDB entry)
Uniprot P17967 142-239! Uniprot P17967 23-141! Uniprot P17967 240-364! Uniprot P17967 365-504
- Domains for 2b5e:
  1. Domain d2b5ea1: 2b5e A:365-504 [127888]
    complexed with ba, gol
  2. Domain d2b5ea2: 2b5e A:142-239 [127889]
    complexed with ba, gol
  3. Domain d2b5ea3: 2b5e A:240-364 [127890]
    complexed with ba, gol
  4. Domain d2b5ea4: 2b5e A:23-141 [127891]
    complexed with ba, gol
Fungus (Humicola insolens) [TaxId:34413] [142357] (3 PDB entries)
Uniprot P55059 227-355! Uniprot P55059 350-459
1. Domain for 2djj:
  - Domain d2djja1: 2djj A:6-121 [131547]
    Other proteins in same PDB: d2djja2
    domain A' only, corresponds to the 4th domain of yeast PDI (2B5E)
2. Domain for 2djk:
  - Domain d2djka1: 2djk A:6-133 [131548]
    Other proteins in same PDB: d2djka2
    domain B' only, corresponds to the 3rd domain of yeast PDI (2B5E)
3. Domain for 2kp2:
  - Domain d2kp2a1: 2kp2 A:6-133 [242607]
    Other proteins in same PDB: d2kp2a2
    automated match to d2djka1
Human (Homo sapiens) [TaxId:9606] [52851] (3 PDB entries)
1. Domain for 1bjx:
  - Domain d1bjxa_: 1bjx A: [32774]
    C-terminal domain
2. Domain for 1mek:
  - Domain d1meka_: 1mek A: [32775]
    N-terminal domain
3. Domain for 2bjx:
  - Domain d2bjxa_: 2bjx A: [32776]
    C-terminal domain
Pyrococcus furiosus [TaxId:2261] [52852] (1 PDB entry)
- Domains for 1a8l:
  1. Domain d1a8la1: 1a8l A:1-119 [32777]
    complexed with zn
  2. Domain d1a8la2: 1a8l A:120-226 [32778]
    complexed with zn
Pyrococcus horikoshii [TaxId:53953] [89702] (1 PDB entry)
glutaredoxin-like protein
- Domains for 1j08:
  1. Domain d1j08a1: 1j08 A:2-119 [83855]
  2. Domain d1j08a2: 1j08 A:120-226 [83856]
  3. Domain d1j08b1: 1j08 B:2-119 [83857]
  4. Domain d1j08b2: 1j08 B:120-226 [83858]
  5. Domain d1j08c1: 1j08 C:2-119 [83859]
  6. Domain d1j08c2: 1j08 C:120-226 [83860]
  7. Domain d1j08d1: 1j08 D:2-119 [83861]
  8. Domain d1j08d2: 1j08 D:120-226 [83862]
  9. Domain d1j08e1: 1j08 E:2-119 [83863]
  10. Domain d1j08e2: 1j08 E:120-226 [83864]
  11. Domain d1j08f1: 1j08 F:2-119 [83865]
  12. Domain d1j08f2: 1j08 F:120-226 [83866]
  13. Domain d1j08g1: 1j08 G:2-119 [83867]
  14. Domain d1j08g2: 1j08 G:120-226 [83868]
  15. Domain d1j08h1: 1j08 H:2-119 [83869]
  16. Domain d1j08h2: 1j08 H:120-226 [83870]

More info for Protein Protein disulfide isomerase, PDI from c.47.1.2: PDI-like

Timeline for Protein Protein disulfide isomerase, PDI from c.47.1.2: PDI-like:

Protein Protein disulfide isomerase, PDI from c.47.1.2: PDI-like first appeared (with stable ids) in SCOP 1.55
Protein Protein disulfide isomerase, PDI from c.47.1.2: PDI-like appears in SCOPe 2.05
Protein Protein disulfide isomerase, PDI from c.47.1.2: PDI-like appears in SCOPe 2.07
Protein Protein disulfide isomerase, PDI from c.47.1.2: PDI-like appears in the current release, SCOPe 2.08