Lineage for Protein: Thioredoxin

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2116932Fold c.47: Thioredoxin fold [52832] (2 superfamilies)
    core: 3 layers, a/b/a; mixed beta-sheet of 4 strands, order 4312; strand 3 is antiparallel to the rest
  4. 2116933Superfamily c.47.1: Thioredoxin-like [52833] (24 families) (S)
  5. 2116934Family c.47.1.1: Thioltransferase [52834] (16 protein domains)
  6. 2117000Protein Thioredoxin [52835] (16 species)

Species:

  1. 2117001Alicyclobacillus acidocaldarius, formerly Bacillus acidocaldarius [TaxId:405212] [52839] (4 PDB entries)
    Uniprot P80579
    1. Domains for 1nsw:
      1. 2117010Domain d1nswa_: 1nsw A: [92097]
        mutant
      2. 2117011Domain d1nswb_: 1nsw B: [92098]
        mutant
      3. 2117012Domain d1nswc_: 1nsw C: [92099]
        mutant
      4. 2117013Domain d1nswd_: 1nsw D: [92100]
        mutant
    2. Domains for 1nw2:
      1. 2117002Domain d1nw2a_: 1nw2 A: [92215]
        complexed with act, cac, zn; mutant
      2. 2117003Domain d1nw2b_: 1nw2 B: [92216]
        complexed with act, cac, zn; mutant
      3. 2117004Domain d1nw2c_: 1nw2 C: [92217]
        complexed with act, cac, zn; mutant
      4. 2117005Domain d1nw2d_: 1nw2 D: [92218]
        complexed with act, cac, zn; mutant
      5. 2117006Domain d1nw2e_: 1nw2 E: [92219]
        complexed with act, cac, zn; mutant
      6. 2117007Domain d1nw2f_: 1nw2 F: [92220]
        complexed with act, cac, zn; mutant
      7. 2117008Domain d1nw2g_: 1nw2 G: [92221]
        complexed with act, cac, zn; mutant
      8. 2117009Domain d1nw2h_: 1nw2 H: [92222]
        complexed with act, cac, zn; mutant
    3. Domain for 1quw:
    4. Domain for 1rqm:
  2. 2117016Escherichia coli K-12 [TaxId:83333] [311109] (2 PDB entries)
    1. Domains for 3dyr:
      1. 2117020Domain d3dyra1: 3dyr A:2-109 [174393]
        Other proteins in same PDB: d3dyra2, d3dyra3
        automated match to d1xoaa_
        mutant
      2. 2117021Domain d3dyrb_: 3dyr B: [174394]
        Other proteins in same PDB: d3dyra2, d3dyra3
        automated match to d1xoaa_
        mutant
    2. Domains for 4x43:
      1. 2117017Domain d4x43a_: 4x43 A: [274347]
        automated match to d4hu9a_
      2. 2117018Domain d4x43b_: 4x43 B: [274344]
        automated match to d4hu9a_
      3. 2117019Domain d4x43c_: 4x43 C: [274350]
        automated match to d4hu9a_
  3. 2117022Escherichia coli [TaxId:562] [52836] (47 PDB entries)
    Uniprot P00274 ! Uniprot P00581
    1. Domains for 1f6m:
      1. 2117092Domain d1f6mc_: 1f6m C: [32725]
        Other proteins in same PDB: d1f6ma1, d1f6ma2, d1f6mb1, d1f6mb2, d1f6me1, d1f6me2, d1f6mf1, d1f6mf2
        protein/RNA complex; complexed with 3aa, fad
      2. 2117093Domain d1f6md_: 1f6m D: [32726]
        Other proteins in same PDB: d1f6ma1, d1f6ma2, d1f6mb1, d1f6mb2, d1f6me1, d1f6me2, d1f6mf1, d1f6mf2
        protein/RNA complex; complexed with 3aa, fad
      3. 2117094Domain d1f6mg_: 1f6m G: [32727]
        Other proteins in same PDB: d1f6ma1, d1f6ma2, d1f6mb1, d1f6mb2, d1f6me1, d1f6me2, d1f6mf1, d1f6mf2
        protein/RNA complex; complexed with 3aa, fad
      4. 2117095Domain d1f6mh_: 1f6m H: [32728]
        Other proteins in same PDB: d1f6ma1, d1f6ma2, d1f6mb1, d1f6mb2, d1f6me1, d1f6me2, d1f6mf1, d1f6mf2
        protein/RNA complex; complexed with 3aa, fad
    2. Domains for 1keb:
      1. 2117028Domain d1keba_: 1keb A: [77341]
        complexed with cu; mutant
      2. 2117029Domain d1kebb_: 1keb B: [77342]
        complexed with cu; mutant
    3. Domains for 1oaz:
      1. 2117102Domain d1oaza_: 1oaz A: [92741]
        Other proteins in same PDB: d1oazh_, d1oazj_, d1oazl_, d1oazn_
        insertion mutant
      2. 2117103Domain d1oazb_: 1oaz B: [92742]
        Other proteins in same PDB: d1oazh_, d1oazj_, d1oazl_, d1oazn_
        insertion mutant
    4. Domain for 1skr:
    5. Domain for 1sks:
    6. Domain for 1skw:
    7. Domains for 1sl0:
      1. 2117098Domain d1sl0b_: 1sl0 B: [105699]
        Other proteins in same PDB: d1sl0a1, d1sl0a2, d1sl0c1, d1sl0c2
        protein/DNA complex; complexed with dad, mg
      2. 2117099Domain d1sl0d_: 1sl0 D: [105702]
        Other proteins in same PDB: d1sl0a1, d1sl0a2, d1sl0c1, d1sl0c2
        protein/DNA complex; complexed with dad, mg
    8. Domain for 1sl1:
    9. Domain for 1sl2:
    10. Domain for 1srx:
    11. Domain for 1t7p:
    12. Domain for 1t8e:
    13. Domain for 1tho:
    14. Domain for 1tk0:
    15. Domain for 1tk5:
    16. Domain for 1tk8:
    17. Domain for 1tkd:
    18. Domain for 1txx:
    19. Domain for 1x9m:
    20. Domain for 1x9s:
    21. Domain for 1x9w:
    22. Domain for 1xoa:
    23. Domain for 1xob:
    24. Domains for 1zcp:
      1. 2117063Domain d1zcpa_: 1zcp A: [162445]
        automated match to d1f6mc_
        mutant
      2. 2117064Domain d1zcpb_: 1zcp B: [162446]
        automated match to d1f6mc_
        mutant
      3. 2117065Domain d1zcpc_: 1zcp C: [162447]
        automated match to d1f6mc_
        mutant
      4. 2117066Domain d1zcpd_: 1zcp D: [162448]
        automated match to d1f6mc_
        mutant
    25. Domain for 1zyq:
    26. Domains for 1zzy:
      1. 2117077Domain d1zzya_: 1zzy A: [162639]
        automated match to d1xoaa_
        mutant
      2. 2117078Domain d1zzyb_: 1zzy B: [162640]
        automated match to d1xoaa_
        mutant
    27. Domains for 2ajq:
      1. 2117084Domain d2ajqb_: 2ajq B: [126890]
        Other proteins in same PDB: d2ajqa1, d2ajqa2, d2ajqf1, d2ajqf2
        automated match to d1xoa__
        protein/DNA complex
      2. 2117085Domain d2ajqi_: 2ajq I: [126891]
        Other proteins in same PDB: d2ajqa1, d2ajqa2, d2ajqf1, d2ajqf2
        automated match to d1xoa__
        protein/DNA complex
    28. Domain for 2bto:
    29. Domains for 2eio:
      1. 2117088Domain d2eioa_: 2eio A: [192695]
        automated match to d2trxa_
      2. 2117089Domain d2eiob_: 2eio B: [192697]
        automated match to d2trxa_
      3. 2117090Domain d2eioc_: 2eio C: [192696]
        automated match to d2trxa_
      4. 2117091Domain d2eiod_: 2eio D: [164050]
        automated match to d1xoaa_
    30. Domains for 2eiq:
      1. 2117030Domain d2eiqa_: 2eiq A: [164051]
        automated match to d1xoaa_
        complexed with cu, mpd
      2. 2117031Domain d2eiqb_: 2eiq B: [164052]
        automated match to d1xoaa_
        complexed with cu, mpd
    31. Domains for 2fch:
      1. 2117070Domain d2fcha_: 2fch A: [164324]
        automated match to d1xoaa_
        complexed with mpd; mutant
      2. 2117071Domain d2fchb_: 2fch B: [164325]
        automated match to d1xoaa_
        complexed with mpd; mutant
      3. 2117072Domain d2fchc_: 2fch C: [164326]
        automated match to d1xoaa_
        complexed with mpd; mutant
      4. 2117073Domain d2fchd_: 2fch D: [164327]
        automated match to d1xoaa_
        complexed with mpd; mutant
      5. 2117074Domain d2fche_: 2fch E: [164328]
        automated match to d1xoaa_
        complexed with mpd; mutant
      6. 2117075Domain d2fchf_: 2fch F: [164329]
        automated match to d1xoaa_
        complexed with mpd; mutant
      7. 2117076Domain d2fchg_: 2fch G: [164330]
        automated match to d1xoaa_
        complexed with mpd; mutant
    32. Domains for 2fd3:
      1. 2117050Domain d2fd3a_: 2fd3 A: [164331]
        automated match to d1xoaa_
        mutant
      2. 2117051Domain d2fd3b_: 2fd3 B: [164332]
        automated match to d1xoaa_
        mutant
    33. Domains for 2h6x:
      1. 2117080Domain d2h6xa_: 2h6x A: [136205]
        automated match to d1xoa__
        complexed with mpd
      2. 2117081Domain d2h6xb_: 2h6x B: [136206]
        automated match to d1xoa__
        complexed with mpd
    34. Domains for 2h6y:
      1. 2117038Domain d2h6ya_: 2h6y A: [164984]
        automated match to d1xoaa_
        complexed with mpd; mutant
      2. 2117039Domain d2h6yb_: 2h6y B: [164985]
        automated match to d1xoaa_
        complexed with mpd; mutant
    35. Domains for 2h6z:
      1. 2117046Domain d2h6za_: 2h6z A: [164986]
        automated match to d1xoaa_
        complexed with mpd; mutant
      2. 2117047Domain d2h6zb_: 2h6z B: [164987]
        automated match to d1xoaa_
        complexed with mpd; mutant
    36. Domains for 2h70:
      1. 2117082Domain d2h70a_: 2h70 A: [164988]
        automated match to d1xoaa_
        complexed with mpd; mutant
      2. 2117083Domain d2h70b_: 2h70 B: [164989]
        automated match to d1xoaa_
        complexed with mpd; mutant
    37. Domains for 2h71:
      1. 2117048Domain d2h71a_: 2h71 A: [164990]
        automated match to d1xoaa_
        complexed with mpd; mutant
      2. 2117049Domain d2h71b_: 2h71 B: [164991]
        automated match to d1xoaa_
        complexed with mpd; mutant
    38. Domains for 2h72:
      1. 2117043Domain d2h72a_: 2h72 A: [164992]
        automated match to d1xoaa_
        complexed with mpd; mutant
      2. 2117044Domain d2h72b_: 2h72 B: [164993]
        automated match to d1xoaa_
        complexed with mpd; mutant
    39. Domains for 2h73:
      1. 2117053Domain d2h73a_: 2h73 A: [164994]
        automated match to d1xoaa_
        complexed with mpd; mutant
      2. 2117054Domain d2h73b_: 2h73 B: [164995]
        automated match to d1xoaa_
        complexed with mpd; mutant
    40. Domains for 2h74:
      1. 2117055Domain d2h74a_: 2h74 A: [164996]
        automated match to d1xoaa_
        complexed with mpd; mutant
      2. 2117056Domain d2h74b_: 2h74 B: [164997]
        automated match to d1xoaa_
        complexed with mpd; mutant
    41. Domains for 2h75:
      1. 2117040Domain d2h75a_: 2h75 A: [164998]
        automated match to d1xoaa_
        complexed with mpd; mutant
      2. 2117041Domain d2h75b_: 2h75 B: [164999]
        automated match to d1xoaa_
        complexed with mpd; mutant
    42. Domains for 2h76:
      1. 2117034Domain d2h76a_: 2h76 A: [165000]
        automated match to d1xoaa_
        complexed with mpd; mutant
      2. 2117035Domain d2h76b_: 2h76 B: [165001]
        automated match to d1xoaa_
        complexed with mpd; mutant
    43. Domain for 2o8v:
    44. Domain for 2tir:
    45. Domains for 2trx:
      1. 2117026Domain d2trxa_: 2trx A: [32719]
        complexed with cu, mpd
      2. 2117027Domain d2trxb_: 2trx B: [32720]
        complexed with cu, mpd
    46. Domains for 4hu7:
      1. 2117023Domain d4hu7a_: 4hu7 A: [202474]
        automated match to d4hu7b_
        complexed with cu, na
      2. 2117024Domain d4hu7b_: 4hu7 B: [197184]
        automated match to d2trxa_
        complexed with cu, na
    47. Domain for 4hu9:
  4. 2117104European aspen (Populus tremula), thioredoxin H [TaxId:113636] [117590] (1 PDB entry)
    Uniprot Q8S3L3
  5. 2117106Fruit fly (Drosophila melanogaster) [TaxId:7227] [117589] (4 PDB entries)
    Uniprot Q9V429
    1. Domains for 1xw9:
      1. 2117116Domain d1xw9a_: 1xw9 A: [116112]
      2. 2117117Domain d1xw9b_: 1xw9 B: [116113]
      3. 2117118Domain d1xw9c_: 1xw9 C: [116114]
      4. 2117119Domain d1xw9d_: 1xw9 D: [116115]
    2. Domains for 1xwa:
      1. 2117107Domain d1xwaa1: 1xwa A:1-106 [116116]
        Other proteins in same PDB: d1xwaa2
        complexed with cd, cl
      2. 2117108Domain d1xwab_: 1xwa B: [116117]
        Other proteins in same PDB: d1xwaa2
        complexed with cd, cl
      3. 2117109Domain d1xwac_: 1xwa C: [116118]
        Other proteins in same PDB: d1xwaa2
        complexed with cd, cl
      4. 2117110Domain d1xwad_: 1xwa D: [116119]
        Other proteins in same PDB: d1xwaa2
        complexed with cd, cl
    3. Domains for 1xwb:
      1. 2117111Domain d1xwba_: 1xwb A: [116120]
        complexed with cd
      2. 2117112Domain d1xwbb_: 1xwb B: [116121]
        complexed with cd
      3. 2117113Domain d1xwbc_: 1xwb C: [116122]
        complexed with cd
      4. 2117114Domain d1xwbd_: 1xwb D: [116123]
        complexed with cd
    4. Domain for 1xwc:
  6. 2117120Green alga (Chlamydomonas reinhardtii) [TaxId:3055] [52838] (4 PDB entries)
    1. Domain for 1dby:
    2. Domains for 1ep7:
      1. 2117121Domain d1ep7a_: 1ep7 A: [64905]
      2. 2117122Domain d1ep7b_: 1ep7 B: [64906]
    3. Domains for 1ep8:
      1. 2117123Domain d1ep8a_: 1ep8 A: [64907]
      2. 2117124Domain d1ep8b_: 1ep8 B: [64908]
    4. Domain for 1tof:
  7. 2117127Human (Homo sapiens) [TaxId:9606] [52842] (30 PDB entries)
    1. Domain for 1aiu:
    2. Domain for 1auc:
    3. Domain for 1cqg:
    4. Domain for 1cqh:
    5. Domain for 1ert:
    6. Domain for 1eru:
    7. Domain for 1erv:
    8. Domain for 1erw:
    9. Domain for 1m7t:
    10. Domain for 1mdi:
    11. Domain for 1mdj:
    12. Domain for 1mdk:
    13. Domain for 1trs:
    14. Domain for 1tru:
    15. Domain for 1trv:
    16. Domain for 1trw:
    17. Domain for 2hsh:
    18. Domains for 2hxk:
      1. 2117138Domain d2hxka_: 2hxk A: [136853]
        automated match to d1auc__
        complexed with eoh
      2. 2117139Domain d2hxkb_: 2hxk B: [136854]
        automated match to d1auc__
        complexed with eoh
      3. 2117140Domain d2hxkc_: 2hxk C: [136855]
        automated match to d1auc__
        complexed with eoh
    19. Domains for 2ifq:
      1. 2117132Domain d2ifqa_: 2ifq A: [137343]
        automated match to d1auc__
        complexed with eoh
      2. 2117133Domain d2ifqb_: 2ifq B: [137344]
        automated match to d1auc__
        complexed with eoh
      3. 2117134Domain d2ifqc_: 2ifq C: [137345]
        automated match to d1auc__
        complexed with eoh
    20. Domain for 2iiy:
    21. Domains for 3e3e:
      1. 2117148Domain d3e3ea_: 3e3e A: [174584]
        automated match to d1erva_
        complexed with p6g; mutant
      2. 2117149Domain d3e3eb_: 3e3e B: [174585]
        automated match to d1erva_
        complexed with p6g; mutant
    22. Domains for 3m9j:
      1. 2117130Domain d3m9ja_: 3m9j A: [180972]
        automated match to d1erva_
        mutant
      2. 2117131Domain d3m9jb_: 3m9j B: [180973]
        automated match to d1erva_
        mutant
    23. Domains for 3m9k:
      1. 2117136Domain d3m9ka_: 3m9k A: [180974]
        automated match to d1erva_
        complexed with d1d, so4; mutant
      2. 2117137Domain d3m9kb_: 3m9k B: [180975]
        automated match to d1erva_
        complexed with d1d, so4; mutant
    24. Domain for 3trx:
    25. Domains for 4ll1:
      1. 2117152Domain d4ll1b_: 4ll1 B: [236596]
        automated match to d2ifqa_
      2. 2117153Domain d4ll1d_: 4ll1 D: [236597]
        automated match to d2ifqa_
    26. Domains for 4ll4:
      1. 2117154Domain d4ll4b_: 4ll4 B: [236598]
        automated match to d2ifqa_
      2. 2117155Domain d4ll4d_: 4ll4 D: [236599]
        automated match to d2ifqa_
    27. Domains for 4oo4:
      1. 2117128Domain d4oo4a_: 4oo4 A: [240719]
        automated match to d4oo4b_
        mutant
      2. 2117129Domain d4oo4b_: 4oo4 B: [236936]
        automated match to d3m9ja_
        mutant
    28. Domain for 4oo5:
    29. Domain for 4trx:
    30. Domain for 5dqy:
  8. 2117168Malaria parasite (Plasmodium falciparum) [TaxId:5833] [102431] (1 PDB entry)
  9. 2117181Nostoc sp. PCC 7120 [TaxId:103690] [52837] (1 PDB entry)
    thioredoxin H
  10. 2117183Plasmodium falciparum [TaxId:36329] [227500] (4 PDB entries)
    1. Domain for 2mmn:
    2. Domain for 2mmo:
    3. Domains for 4j56:
      1. 2117184Domain d4j56e1: 4j56 E:2-104 [227506]
        Other proteins in same PDB: d4j56e2, d4j56f2, d4j56g2, d4j56h2
        automated match to d1ep7a_
        complexed with fad
      2. 2117185Domain d4j56f1: 4j56 F:2-104 [227508]
        Other proteins in same PDB: d4j56e2, d4j56f2, d4j56g2, d4j56h2
        automated match to d1ep7a_
        complexed with fad
      3. 2117186Domain d4j56g1: 4j56 G:2-104 [227509]
        Other proteins in same PDB: d4j56e2, d4j56f2, d4j56g2, d4j56h2
        automated match to d1ep7a_
        complexed with fad
      4. 2117187Domain d4j56h1: 4j56 H:2-104 [227507]
        Other proteins in same PDB: d4j56e2, d4j56f2, d4j56g2, d4j56h2
        automated match to d1ep7a_
        complexed with fad
    4. Domains for 4j57:
      1. 2117188Domain d4j57e_: 4j57 E: [227504]
        automated match to d1ep7a_
        complexed with fad, gol
      2. 2117189Domain d4j57f_: 4j57 F: [227505]
        automated match to d1ep7a_
        complexed with fad, gol
  11. 2117192Spinach (Spinacia oleracea), thioredoxin F [TaxId:3562] [52840] (2 PDB entries)
    1. Domains for 1f9m:
      1. 2117193Domain d1f9ma_: 1f9m A: [32736]
        short form
      2. 2117194Domain d1f9mb_: 1f9m B: [32737]
        short form
    2. Domain for 1faa:
  12. 2117196Spinach (Spinacia oleracea), thioredoxin M [TaxId:3562] [52841] (3 PDB entries)
    1. Domains for 1fb0:
      1. 2117199Domain d1fb0a_: 1fb0 A: [32741]
      2. 2117200Domain d1fb0b_: 1fb0 B: [32742]
    2. Domains for 1fb6:
      1. 2117197Domain d1fb6a_: 1fb6 A: [32739]
      2. 2117198Domain d1fb6b_: 1fb6 B: [32740]
    3. Domain for 1gl8:
  13. 2117202Staphylococcus aureus [TaxId:1280] [187358] (5 PDB entries)
    1. Domain for 2o7k:
    2. Domain for 2o85:
    3. Domain for 2o87:
    4. Domain for 2o89:
    5. Domains for 3die:
      1. 2117203Domain d3diea1: 3die A:1-104 [173978]
        Other proteins in same PDB: d3diea2, d3dieb2
        automated match to d1nswa_
        complexed with cd, fe; mutant
      2. 2117204Domain d3dieb1: 3die B:1-104 [173979]
        Other proteins in same PDB: d3diea2, d3dieb2
        automated match to d1nswa_
        complexed with cd, fe; mutant
  14. 2117209Thale cress (Arabidopsis thaliana) [TaxId:3702] [110603] (1 PDB entry)
    Uniprot P29448 #
  15. 2117211Trichomonas vaginalis [TaxId:5722] [187687] (1 PDB entry)
  16. 2117214Trypanosome (Trypanosoma brucei) [TaxId:5691] [102430] (1 PDB entry)

More info for Protein Thioredoxin from c.47.1.1: Thioltransferase

Timeline for Protein Thioredoxin from c.47.1.1: Thioltransferase: