Lineage for Superfamily c.47.1: Thioredoxin-like

  1. Root: SCOPe 2.02
  2. 1143363Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1168056Fold c.47: Thioredoxin fold [52832] (2 superfamilies)
    core: 3 layers, a/b/a; mixed beta-sheet of 4 strands, order 4312; strand 3 is antiparallel to the rest
  4. 1168057Superfamily c.47.1: Thioredoxin-like [52833] (24 families) (S)

Families:

  1. 1168058c.47.1.1: Thioltransferase [52834] (16 proteins)
  2. 1168367c.47.1.2: PDI-like [52849] (2 proteins)
    duplication: contains two tandem repeats of this fold
  3. 1168413c.47.1.3: Calsequestrin [52855] (1 protein)
    duplication: contains three tandem repeats of this fold
  4. 1168419c.47.1.5: Glutathione S-transferase (GST), N-terminal domain [52862] (18 proteins)
  5. 1168970c.47.1.6: Phosducin [52888] (1 protein)
  6. 1168978c.47.1.7: ERP29 N domain-like [52892] (2 proteins)
  7. 1168993c.47.1.8: spliceosomal protein U5-15Kd [52895] (2 proteins)
  8. 1169004c.47.1.9: DsbC/DsbG C-terminal domain-like [52898] (2 proteins)
    elaborated common fold
  9. 1169030c.47.1.10: Glutathione peroxidase-like [52901] (29 proteins)
  10. 1169496c.47.1.11: Thioredoxin-like 2Fe-2S ferredoxin [52918] (1 protein)
  11. 1169507c.47.1.12: ArsC-like [69518] (4 proteins)
    Pfam PF03960
  12. 1169534c.47.1.13: DsbA-like [100953] (4 proteins)
    contains an all-alpha subdomain insertion
  13. 1169601c.47.1.14: SH3BGR (SH3-binding, glutamic acid-rich protein-like) [102446] (1 protein)
    related to glutaredoxin 1 (GRX1) but lacks both conserved cysteine residues
  14. 1169607c.47.1.15: KaiB-like [102449] (3 proteins)
    Pfam PF07689; contains members with alternative folds
  15. 1169634c.47.1.16: Txnl5-like [110612] (1 protein)
    Pfam PF06110
  16. 1169640c.47.1.17: YuzD-like [117605] (1 protein)
    Pfam PF07315
  17. 1169644c.47.1.18: YKR049C-like [142395] (1 protein)
    Pfam PF07955; DUF1687; contains an all-alpha insert subdomain
  18. 1169648c.47.1.19: Atu2684-like [142398] (1 protein)
    Pfam PF06764; DUF1223; contains extra C-terminal domain of Immunoglobulin-like fold (48725), intimately associated with the N-terminal thioredixin-like domain and contributing to the active site
  19. 1169652c.47.1.20: HyaE-like [142401] (2 proteins)
    Pfam PF07449; have evolved a different function; contains no conserved cysteine residues
  20. 1169674c.47.1.21: NQO2-like [142405] (1 protein)
    complex I 24 kDa subunit; contains 2Fe-2S cluster in the active site; includes extra N-terminal four-helical bundle
  21. 1169681c.47.1.22: Mitochondrial ribosomal protein L51/S25/CI-B8 domain [142408] (1 protein)
    Pfam PF05047; "minimalized" version of the thioredoxin-like fold; variable positions for cysteine residues in the putative active site
  22. 1169685c.47.1.23: Selenoprotein W-related [142411] (4 proteins)
    Pfam PF05169; "minimalized" version of the thioredoxin-like fold
  23. 1169721c.47.1.24: UAS domain [159589] (1 protein)
    SMART 00594
  24. 1169725c.47.1.0: automated matches [191312] (1 protein)
    not a true family

More info for Superfamily c.47.1: Thioredoxin-like

Timeline for Superfamily c.47.1: Thioredoxin-like: