SCOP 1.65: Family c.46.1.1: Cell cycle control phosphatase, catalytic domain

Lineage for Family c.46.1.1: Cell cycle control phosphatase, catalytic domain

1. Root: SCOP 1.65

2. Class c: Alpha and beta proteins (a/b) [51349] (121 folds)

3. Fold c.46: Rhodanese/Cell cycle control phosphatase [52820] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 5 strands, order 32451

4. Superfamily c.46.1: Rhodanese/Cell cycle control phosphatase [52821] (3 families)
   the active site structure is similar to those of the families I and II protein phosphatases; the topology can be related by a different circular permutation to the family I topology

5. Family c.46.1.1: Cell cycle control phosphatase, catalytic domain [52822] (3 proteins)

Proteins:

1. CDC25a [52823] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [52824] (1 PDB entry)

2. CDC25b [52825] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [52826] (4 PDB entries)

3. Erk2 binding domain of Mapk phosphatase mkp-3 [69507] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [69508] (1 PDB entry)

More info for Family c.46.1.1: Cell cycle control phosphatase, catalytic domain

Timeline for Family c.46.1.1: Cell cycle control phosphatase, catalytic domain:

• Family c.46.1.1: Cell cycle control phosphatase, catalytic domain first appeared (with stable ids) in SCOP 1.55
  
• Family c.46.1.1: Cell cycle control phosphatase, catalytic domain appears in SCOP 1.63
  
• Family c.46.1.1: Cell cycle control phosphatase, catalytic domain appears in SCOP 1.67
  
• Family c.46.1.1: Cell cycle control phosphatase, catalytic domain appears in the current release, SCOPe 2.08