Class c: Alpha and beta proteins (a/b) [51349] (141 folds) |
Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily) core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423 |
Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (5 families) share with the family I the common active site structure with a circularly permuted topology |
Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (6 proteins) has an extension to the beta-sheet of 3 antiparallel strands before strand 4 |
Protein Tyrosine phosphatase [52806] (7 species) |
Species Human (Homo sapiens), 1B [TaxId:9606] [52807] (91 PDB entries) |
Domain d1a5ya_: 1a5y A: [32673] cysteinyl-phosphate intermediate |
Domain d1aaxa_: 1aax A: [32657] complexed with bpm, mo6; mutant |
Domain d1bzca_: 1bzc A: [32670] complexed with tpi |
Domain d1bzha_: 1bzh A: [32664] complexed with inh |
Domain d1bzja_: 1bzj A: [32667] complexed with inh |
Domain d1c83a_: 1c83 A: [32660] complexed with oai |
Domain d1c84a_: 1c84 A: [32671] complexed with 761 |
Domain d1c85a_: 1c85 A: [32674] complexed with oba |
Domain d1c86a_: 1c86 A: [32668] complexed with opa; mutant |
Domain d1c87a_: 1c87 A: [32663] complexed with opa |
Domain d1c88a_: 1c88 A: [32659] complexed with ota |
Domain d1ecva_: 1ecv A: [32661] complexed with 878, act |
Domain d1eena_: 1een A: [32658] complexed with acy, mg, pbf; mutant |
Domain d1eeoa_: 1eeo A: [32655] complexed with mg; mutant |
Domain d1g1fa_: 1g1f A: [32662] mutant |
Domain d1g1ga_: 1g1g A: [32669] mutant |
Domain d1g1ha_: 1g1h A: [32672] mutant |
Domain d1g7fa_: 1g7f A: [60330] complexed with inz |
Domain d1g7ga_: 1g7g A: [60331] complexed with inx |
Domain d1gfya_: 1gfy A: [32666] complexed with col; mutant |
Domain d1i57a_: 1i57 A: [61772] complexed with cl, mg; mutant |
Domain d1jf7a_: 1jf7 A: [66619] |
Domain d1jf7b_: 1jf7 B: [66620] complexed with tbh |
Domain d1kaka_: 1kak A: [72253] complexed with fnp |
Domain d1kava_: 1kav A: [72266] complexed with fep |
Domain d1l8ga_: 1l8g A: [73689] complexed with dbd |
Domain d1lqfa_: 1lqf A: [74187] |
Domain d1lqfb_: 1lqf B: [74188] |
Domain d1lqfc_: 1lqf C: [74189] |
Domain d1lqfd_: 1lqf D: [74190] complexed with bgd |
Domain d1nl9a_: 1nl9 A: [85847] complexed with 989 |
Domain d1nnya_: 1nny A: [85912] complexed with 515 |
Domain d1no6a_: 1no6 A: [85922] complexed with 794 |
Domain d1nwea_: 1nwe A: [86298] complexed with fg1; mutant |
Domain d1nwla_: 1nwl A: [86300] complexed with 964, mo6; mutant |
Domain d1nz7a_: 1nz7 A: [86443] complexed with 901 |
Domain d1oemx_: 1oem X: [86916] |
Domain d1oeox_: 1oeo X: [86917] complexed with ocs |
Domain d1oesa_: 1oes A: [86920] complexed with mg |
Domain d1oeta_: 1oet A: [86921] complexed with cea, mg |
Domain d1oeua_: 1oeu A: [86922] complexed with csw, mg |
Domain d1oeva_: 1oev A: [86923] complexed with mg, ocs |
Domain d1onya_: 1ony A: [87180] complexed with 588 |
Domain d1onza_: 1onz A: [87181] complexed with 968 |
Domain d1pa1a_: 1pa1 A: [94404] complexed with cl, mg; mutant |
Domain d1ph0a_: 1ph0 A: [88074] complexed with 418 |
Domain d1ptta_: 1ptt A: [32677] complexed with ace, phs; mutant |
Domain d1ptua_: 1ptu A: [32675] complexed with nh2, phs; mutant |
Domain d1ptva_: 1ptv A: [32665] complexed with phs; mutant |
Domain d1ptya_: 1pty A: [32656] complexed with mo6; mutant |
Domain d1pxha_: 1pxh A: [95288] complexed with acy, mg, sna |
Domain d1pyna_: 1pyn A: [95369] complexed with 941 |
Domain d1q1ma_: 1q1m A: [95595] complexed with 234 |
Domain d1q6ja_: 1q6j A: [95979] complexed with 335 |
Domain d1q6ma_: 1q6m A: [95983] complexed with p27 |
Domain d1q6na_: 1q6n A: [95984] |
Domain d1q6nb_: 1q6n B: [95985] complexed with cl, mg, p90 |
Domain d1q6pa_: 1q6p A: [95988] |
Domain d1q6pb_: 1q6p B: [95989] complexed with 213, cl |
Domain d1q6sa_: 1q6s A: [95994] |
Domain d1q6sb_: 1q6s B: [95995] complexed with 214, cl, mg, mpd |
Domain d1q6ta_: 1q6t A: [95996] |
Domain d1q6tb_: 1q6t B: [95997] complexed with 600, mg |
Domain d1qxka_: 1qxk A: [96532] complexed with 429 |
Domain d1suga_: 1sug A: [106022] complexed with gol, trs |
Domain d1t48a_: 1t48 A: [106402] complexed with bb3 |
Domain d1t49a_: 1t49 A: [106403] complexed with 892, mo6 |
Domain d1t4ja_: 1t4j A: [106422] complexed with frj |
Domain d1waxa1: 1wax A:2-299 [120824] automatically matched to d1q1ma_ complexed with lo1, mg |
Domain d1xboa_: 1xbo A: [115079] complexed with ix1 |
Domain d2azra1: 2azr A:2-298 [127614] automatically matched to d1q1ma_ complexed with 982 |
Domain d2b07a1: 2b07 A:2-298 [127625] automatically matched to d1q1ma_ complexed with 598 |
Domain d2b4sa1: 2b4s A:2-292 [127853] Other proteins in same PDB: d2b4sb1, d2b4sd1 automatically matched to d1g1ga_ complexed with so4 |
Domain d2bgda1: 2bgd A:2-298 [128474] automatically matched to d1q1ma_ complexed with cl, na, po4, t1d |
Domain d2bgea1: 2bge A:2-298 [128475] automatically matched to d1q1ma_ complexed with t2d |
Domain d2cm2a1: 2cm2 A:2-283 [130610] automatically matched to d1ptta_ complexed with mpd |
Domain d2cm3a1: 2cm3 A:7-281 [130611] automatically matched to d1ptta_ complexed with ca |
Domain d2cm3b1: 2cm3 B:7-281 [130612] automatically matched to d1ptta_ complexed with ca |
Domain d2cm7a1: 2cm7 A:3-299 [130616] automatically matched to d1q1ma_ complexed with izd |
Domain d2cm8a1: 2cm8 A:3-299 [130617] automatically matched to d1q1ma_ complexed with f16, mg |
Domain d2cmaa1: 2cma A:3-299 [130618] automatically matched to d1q1ma_ complexed with f20 |
Domain d2cmba1: 2cmb A:2-281 [130619] automatically matched to d1ptta_ complexed with bog, f17 |
Domain d2cmca1: 2cmc A:2-281 [130620] automatically matched to d1ptta_ complexed with bog, dfm, so4 |
Domain d2cnea1: 2cne A:2-281 [130640] automatically matched to d1ptta_ complexed with bog, dfj, so4 |
Domain d2cnfa1: 2cnf A:3-299 [130641] automatically matched to d1q1ma_ complexed with f32, mg |
Domain d2cnga1: 2cng A:3-299 [130642] automatically matched to d1q1ma_ complexed with gol, ize, mg |
Domain d2cnha1: 2cnh A:3-299 [130643] automatically matched to d1q1ma_ complexed with ca, izb |
Domain d2cnia1: 2cni A:3-299 [130644] automatically matched to d1q1ma_ complexed with izf, mg |
Domain d2f6ta1: 2f6t A:2-298 [133060] automatically matched to d1q1ma_ complexed with 1c2, cl, mg |
Domain d2f6va1: 2f6v A:2-298 [133063] automatically matched to d1q1ma_ complexed with cl, mg, sk2 |
Domain d2f6wa1: 2f6w A:2-298 [133064] automatically matched to d1q1ma_ complexed with cl, mg, un3 |
Domain d2f6ya1: 2f6y A:2-298 [133067] automatically matched to d1q1ma_ complexed with cl, ent, mg |
Domain d2f6za1: 2f6z A:2-298 [133068] automatically matched to d1q1ma_ complexed with cl, mg, un5 |
Domain d2f70a1: 2f70 A:2-298 [133069] automatically matched to d1q1ma_ complexed with cl, mg, un6 |
Domain d2f71a1: 2f71 A:2-298 [133070] automatically matched to d1q1ma_ complexed with cl, mg, un7 |
Domain d2h4ga1: 2h4g A:2-283 [136074] automatically matched to d1ptta_ complexed with 694 |
Domain d2h4ka1: 2h4k A:2-283 [136077] automatically matched to d1ptta_ complexed with 509 |
Domain d2hb1a1: 2hb1 A:2-283 [136304] automatically matched to d1ptta_ complexed with 512 |
Domain d2hnpa_: 2hnp A: [32678] |
Domain d2hnqa_: 2hnq A: [32676] complexed with wo4 |
Timeline for Species Human (Homo sapiens), 1B [TaxId:9606] from c.45.1.2 Tyrosine phosphatase: