Lineage for Protein: Tyrosine phosphatase

  1. Root: SCOP 1.67
  2. 383641Class c: Alpha and beta proteins (a/b) [51349] (130 folds)
  3. 395608Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. 395609Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (3 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 395648Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (5 proteins)
    has an extension to the beta-sheet of 3 antiparallel strands before strand 4
  6. 395674Protein Tyrosine phosphatase [52806] (7 species)

Species:

  1. 395675Human (Homo sapiens), 1B [TaxId:9606] [52807] (58 PDB entries)
    1. Domain for 1a5y:
    2. Domain for 1aax:
    3. Domain for 1bzc:
    4. Domain for 1bzh:
    5. Domain for 1bzj:
    6. Domain for 1c83:
    7. Domain for 1c84:
    8. Domain for 1c85:
    9. Domain for 1c86:
    10. Domain for 1c87:
    11. Domain for 1c88:
    12. Domain for 1ecv:
    13. Domain for 1een:
    14. Domain for 1eeo:
    15. Domain for 1g1f:
    16. Domain for 1g1g:
    17. Domain for 1g1h:
    18. Domain for 1g7f:
    19. Domain for 1g7g:
    20. Domain for 1gfy:
    21. Domain for 1i57:
    22. Domains for 1jf7:
      1. 395707Domain d1jf7a_: 1jf7 A: [66619]
      2. 395708Domain d1jf7b_: 1jf7 B: [66620]
        complexed with tbh
    23. Domain for 1kak:
    24. Domain for 1kav:
    25. Domain for 1l8g:
    26. Domains for 1lqf:
      1. 395733Domain d1lqfa_: 1lqf A: [74187]
      2. 395734Domain d1lqfb_: 1lqf B: [74188]
      3. 395735Domain d1lqfc_: 1lqf C: [74189]
      4. 395736Domain d1lqfd_: 1lqf D: [74190]
        complexed with bgd
    27. Domain for 1nl9:
    28. Domain for 1nny:
    29. Domain for 1no6:
    30. Domain for 1nwe:
    31. Domain for 1nwl:
    32. Domain for 1nz7:
    33. Domain for 1oem:
    34. Domain for 1oeo:
    35. Domain for 1oes:
    36. Domain for 1oet:
    37. Domain for 1oeu:
    38. Domain for 1oev:
    39. Domain for 1ony:
    40. Domain for 1onz:
    41. Domain for 1pa1:
    42. Domain for 1ph0:
    43. Domain for 1ptt:
    44. Domain for 1ptu:
    45. Domain for 1ptv:
    46. Domain for 1pty:
    47. Domain for 1pxh:
    48. Domain for 1pyn:
    49. Domain for 1q1m:
    50. Domain for 1q6j:
    51. Domain for 1q6m:
    52. Domains for 1q6n:
      1. 395696Domain d1q6na_: 1q6n A: [95984]
      2. 395697Domain d1q6nb_: 1q6n B: [95985]
        complexed with cl, mg, p90
    53. Domains for 1q6p:
      1. 395719Domain d1q6pa_: 1q6p A: [95988]
      2. 395720Domain d1q6pb_: 1q6p B: [95989]
        complexed with 213, cl
    54. Domains for 1q6s:
      1. 395702Domain d1q6sa_: 1q6s A: [95994]
      2. 395703Domain d1q6sb_: 1q6s B: [95995]
        complexed with 214, cl, mg, mpd
    55. Domains for 1q6t:
      1. 395721Domain d1q6ta_: 1q6t A: [95996]
      2. 395722Domain d1q6tb_: 1q6t B: [95997]
        complexed with 600, mg
    56. Domain for 1qxk:
    57. Domain for 2hnp:
    58. Domain for 2hnq:
  2. 395742Human (Homo sapiens), mu [TaxId:9606] [52808] (1 PDB entry)
    receptor protein tyrosine phosphatase mu, domain 1
  3. 395745Human (Homo sapiens), shp-1 [TaxId:9606] [52811] (2 PDB entries)
    1. Domain for 1fpr:
      • 395746Domain d1fpra_: 1fpr A: [59949]
        complex with an in vitro peptide substrate py469 derived from shps-1, chain B
        mutant
    2. Domain for 1gwz:
  4. 395748Human (Homo sapiens), shp-2 [TaxId:9606] [52810] (1 PDB entry)
  5. 395751Human (Homo sapiens), T-cell [TaxId:9606] [75233] (1 PDB entry)
    non-receptor type 2
  6. 395753Mouse (Mus musculus) [TaxId:10090] [52809] (1 PDB entry)
    receptor protein tyrosine phosphatase alpha, domain 1
  7. 395756Mouse (Mus musculus), ptp-sl/br7 [TaxId:10090] [64051] (1 PDB entry)

More info for Protein Tyrosine phosphatase from c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases

Timeline for Protein Tyrosine phosphatase from c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases: