SCOPe 2.01: Family c.45.1.1: Dual specificity phosphatase-like

Lineage for Family c.45.1.1: Dual specificity phosphatase-like

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.1: Dual specificity phosphatase-like [52800] (9 proteins)

Proteins:

1. Kinase associated phosphatase (kap) [64049] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [64050] (2 PDB entries)

2. Mapk phosphatase [52803] (2 species)

   1. Species Human (Homo sapiens), pac-1 [TaxId:9606] [75232] (1 PDB entry)

   2. Species Human (Homo sapiens), pyst1 (mkp3) [TaxId:9606] [52804] (1 PDB entry)

3. mRNA capping enzyme, triphosphatase domain [64047] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [64048] (2 PDB entries)

4. Phoshphoinositide phosphatase Pten (Pten tumor suppressor), N-terminal domain [52818] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [52819] (1 PDB entry)

5. Proline directed phosphatase CDC14b2 [89698] (1 species)
   duplication: consists of two structurally similar domains with the catalytic site being in the C-terminal domain

   • Species Human (Homo sapiens) [TaxId:9606] [89699] (3 PDB entries)

6. Protein tyrosine phosphatase type IVa [102418] (3 species)

   1. Species Human (Homo sapiens), pr-1 [TaxId:9606] [117578] (1 PDB entry)
      Uniprot Q93096 9-160

   2. Species Human (Homo sapiens), pr-3 [TaxId:9606] [102419] (2 PDB entries)
      Uniprot O75365 1-162 # 99% sequence identity

   3. Species Norway rat (Rattus norvegicus) [TaxId:10116] [188182] (1 PDB entry)

7. Putative phosphatase At1g05000 [117579] (1 species)

   • Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [117580] (2 PDB entries)
     Uniprot Q9ZVN4 52-201

8. VH1-related dual-specificity phosphatase, VHR [52801] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [52802] (2 PDB entries)

9. automated matches [190696] (1 species)
   not a true protein

   • Species Human (Homo sapiens) [TaxId:9606] [188122] (5 PDB entries)

More info for Family c.45.1.1: Dual specificity phosphatase-like

Timeline for Family c.45.1.1: Dual specificity phosphatase-like:

• Family c.45.1.1: Dual specificity phosphatase-like first appeared (with stable ids) in SCOP 1.55, called Family c.45.1.1: Dual-specificity phosphatases
  
• Family c.45.1.1: Dual specificity phosphatase-like appears in SCOP 1.75
  
• Family c.45.1.1: Dual specificity phosphatase-like appears in SCOPe 2.02
  
• Family c.45.1.1: Dual specificity phosphatase-like appears in the current release, SCOPe 2.08