Lineage for Family c.45.1.1: Dual specificity phosphatase-like

  1. Root: SCOP 1.75
  2. 814173Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 833132Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. 833133Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (5 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 833134Family c.45.1.1: Dual specificity phosphatase-like [52800] (8 proteins)

Proteins:

  1. 833135Kinase associated phosphatase (kap) [64049] (1 species)
  2. 833144Mapk phosphatase [52803] (2 species)
    1. 833145Species Human (Homo sapiens), pac-1 [TaxId:9606] [75232] (1 PDB entry)
    2. 833147Species Human (Homo sapiens), pyst1 (mkp3) [TaxId:9606] [52804] (1 PDB entry)
  3. 833149mRNA capping enzyme, triphosphatase domain [64047] (1 species)
  4. 833153Phoshphoinositide phosphatase Pten (Pten tumor suppressor), N-terminal domain [52818] (1 species)
  5. 833156Proline directed phosphatase CDC14b2 [89698] (1 species)
    duplication: consists of two structurally similar domains with the catalytic site being in the C-terminal domain
  6. 833164Protein tyrosine phosphatase type IVa [102418] (2 species)
    1. 833165Species Human (Homo sapiens), pr-1 [TaxId:9606] [117578] (1 PDB entry)
      Uniprot Q93096 9-160
    2. 833169Species Human (Homo sapiens), pr-3 [TaxId:9606] [102419] (2 PDB entries)
      Uniprot O75365 1-162 # 99% sequence identity
  7. 833172Putative phosphatase At1g05000 [117579] (1 species)
  8. 833178VH1-related dual-specificity phosphatase, VHR [52801] (1 species)

More info for Family c.45.1.1: Dual specificity phosphatase-like

Timeline for Family c.45.1.1: Dual specificity phosphatase-like: