Lineage for Family c.45.1.1: Dual specificity phosphatase-like

  1. Root: SCOP 1.65
  2. 305035Class c: Alpha and beta proteins (a/b) [51349] (121 folds)
  3. 315136Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1432
  4. 315137Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (2 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 315138Family c.45.1.1: Dual specificity phosphatase-like [52800] (6 proteins)

Proteins:

  1. 315139Kinase associated phosphatase (kap) [64049] (1 species)
  2. 315148Mapk phosphatase [52803] (2 species)
    1. 315149Species Human (Homo sapiens), pac-1 [TaxId:9606] [75232] (2 PDB entries)
    2. 315152Species Human (Homo sapiens), pyst1 (mkp3) [TaxId:9606] [52804] (1 PDB entry)
  3. 315154mRNA capping enzyme, triphosphatase domain [64047] (1 species)
  4. 315158Phoshphoinositide phosphatase Pten (Pten tumor suppressor), N-terminal domain [52818] (1 species)
  5. 315161Proline directed phosphatase CDC14b2 [89698] (1 species)
    duplication: consists of two structurally similar domains with the catalytic site being in the C-terminal domain
  6. 315169VH1-related dual-specificity phosphatase, VHR [52801] (1 species)

More info for Family c.45.1.1: Dual specificity phosphatase-like

Timeline for Family c.45.1.1: Dual specificity phosphatase-like: