Lineage for Family c.45.1.1: Dual specificity phosphatase-like

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2116263Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. 2116264Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 2116265Family c.45.1.1: Dual specificity phosphatase-like [52800] (9 protein domains)

Protein Domains:

  1. 2116266Kinase associated phosphatase (kap) [64049] (1 species)
  2. 2116275Mapk phosphatase [52803] (2 species)
    1. 2116276Species Human (Homo sapiens), pac-1 [TaxId:9606] [75232] (1 PDB entry)
    2. 2116278Species Human (Homo sapiens), pyst1 (mkp3) [TaxId:9606] [52804] (1 PDB entry)
  3. 2116280mRNA capping enzyme, triphosphatase domain [64047] (1 species)
  4. 2116284Phoshphoinositide phosphatase Pten (Pten tumor suppressor), N-terminal domain [52818] (1 species)
  5. 2116287Proline directed phosphatase CDC14b2 [89698] (1 species)
    duplication: consists of two structurally similar domains with the catalytic site being in the C-terminal domain
  6. 2116295Protein tyrosine phosphatase type IVa [102418] (3 species)
    1. 2116296Species Human (Homo sapiens), pr-1 [TaxId:9606] [117578] (1 PDB entry)
      Uniprot Q93096 9-160
    2. 2116300Species Human (Homo sapiens), pr-3 [TaxId:9606] [102419] (4 PDB entries)
      Uniprot O75365 1-162 # 99% sequence identity
    3. 2116304Species Norway rat (Rattus norvegicus) [TaxId:10116] [188182] (1 PDB entry)
  7. 2116308Putative phosphatase At1g05000 [117579] (1 species)
  8. 2116314VH1-related dual-specificity phosphatase, VHR [52801] (1 species)
  9. 2116321automated matches [190696] (3 species)
    not a true protein
    1. 2116322Species Human (Homo sapiens) [TaxId:9606] [188122] (15 PDB entries)
    2. 2116360Species Norway rat (Rattus norvegicus) [TaxId:10116] [225022] (2 PDB entries)
    3. 2277914Species Mus musculus [TaxId:10090] [321215] (3 PDB entries)

More info for Family c.45.1.1: Dual specificity phosphatase-like

Timeline for Family c.45.1.1: Dual specificity phosphatase-like: