Lineage for Protein: Initiation factor 4a

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2109203Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2109204Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families) (S)
    division into families based on beta-sheet topologies
  5. 2113231Family c.37.1.19: Tandem AAA-ATPase domain [81268] (24 protein domains)
    duplication: tandem repeat of two RecA-like (AAA) domains
  6. 2113298Protein Initiation factor 4a [52706] (2 species)
    homologous to UvrB

Species:

  1. 2113299Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52707] (4 PDB entries)
    1. Domain for 1fuk:
    2. Domains for 1fuu:
      1. 2113303Domain d1fuua_: 1fuu A: [32412]
      2. 2113304Domain d1fuub1: 1fuu B:11-225 [32413]
      3. 2113305Domain d1fuub2: 1fuu B:226-394 [32414]
    3. Domain for 1qde:
      • 2113301Domain d1qdea_: 1qde A: [32410]
        N-terminal AAA domain; P-loop is empty and in a non-canonical conformation
        complexed with so4
    4. Domain for 1qva:
      • 2113302Domain d1qvaa_: 1qva A: [32411]
        N-terminal AAA domain; P-loop is empty and in a non-canonical conformation
  2. 2113306Human (Homo sapiens) [TaxId:9606] [142305] (2 PDB entries)
    Uniprot P60842 21-238
    4A-I
    1. Domains for 2g9n:
      1. 2113307Domain d2g9na1: 2g9n A:21-238 [134814]
      2. 2113308Domain d2g9nb_: 2g9n B: [134815]
        automated match to d1fuua_
    2. Domains for 2zu6:
      1. 2113309Domain d2zu6a1: 2zu6 A:20-239 [231730]
        Other proteins in same PDB: d2zu6a3, d2zu6d3
        automated match to d2zu6c1
        protein/RNA complex; complexed with acy, edo
      2. 2113310Domain d2zu6a2: 2zu6 A:246-401 [231731]
        Other proteins in same PDB: d2zu6a3, d2zu6d3
        automated match to d2zu6c2
        protein/RNA complex; complexed with acy, edo
      3. 2113311Domain d2zu6c1: 2zu6 C:25-239 [207979]
        Other proteins in same PDB: d2zu6a3, d2zu6d3
        automated match to d1xtia1
        protein/RNA complex; complexed with acy, edo
      4. 2113312Domain d2zu6c2: 2zu6 C:246-398 [207980]
        Other proteins in same PDB: d2zu6a3, d2zu6d3
        automated match to d1xtia2
        protein/RNA complex; complexed with acy, edo
      5. 2113313Domain d2zu6d1: 2zu6 D:20-239 [231732]
        Other proteins in same PDB: d2zu6a3, d2zu6d3
        automated match to d2zu6c1
        protein/RNA complex; complexed with acy, edo
      6. 2113314Domain d2zu6d2: 2zu6 D:246-402 [231733]
        Other proteins in same PDB: d2zu6a3, d2zu6d3
        automated match to d2zu6c2
        protein/RNA complex; complexed with acy, edo
      7. 2113315Domain d2zu6f1: 2zu6 F:245-398 [207981]
        Other proteins in same PDB: d2zu6a3, d2zu6d3
        automated match to d1xtia2
        protein/RNA complex; complexed with acy, edo
      8. 2113316Domain d2zu6f2: 2zu6 F:87-231 [239079]
        Other proteins in same PDB: d2zu6a3, d2zu6d3
        protein/RNA complex; complexed with acy, edo

More info for Protein Initiation factor 4a from c.37.1.19: Tandem AAA-ATPase domain

Timeline for Protein Initiation factor 4a from c.37.1.19: Tandem AAA-ATPase domain: