SCOP 1.65: Family c.37.1.10: Nitrogenase iron protein-like

Lineage for Family c.37.1.10: Nitrogenase iron protein-like

1. Root: SCOP 1.65

2. Class c: Alpha and beta proteins (a/b) [51349] (121 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (21 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.10: Nitrogenase iron protein-like [52652] (10 proteins)
   core: parallel beta-sheet of 7 strands; order 3241567

Proteins:

1. Adenylosuccinate synthetase, PurA [52655] (4 species)
   common fold is interrupted by an all-alpha subdomain, residues 100-200

   1. Species Bread wheat (Triticum aestivum) [TaxId:4565] [52658] (1 PDB entry)

   2. Species Escherichia coli [TaxId:562] [52656] (23 PDB entries)

   3. Species Mouse (Mus musculus) [TaxId:10090] [69491] (8 PDB entries)

   4. Species Mouse-ear cress (Arabidopsis thaliana) [TaxId:3702] [52657] (1 PDB entry)

2. Arsenite-translocating ATPase ArsA [52668] (1 species)
   Duplication: consists of two domains of this fold arranged as the NIP subunits in the dimer

   • Species Escherichia coli [TaxId:562] [52669] (4 PDB entries)

3. Cell division regulator MinD [64019] (3 species)

   1. Species Archaeon Archaeoglobus fulgidus [TaxId:2234] [64020] (1 PDB entry)

   2. Species Archaeon Pyrococcus furiosus [TaxId:2261] [64021] (2 PDB entries)

   3. Species Archaeon Pyrococcus horikoshii [TaxId:53953] [64022] (1 PDB entry)

4. Dethiobiotin synthetase [52653] (1 species)

   • Species Escherichia coli [TaxId:562] [52654] (13 PDB entries)

5. Formyltetrahydrofolate synthetase [52659] (1 species)
   modified P-loop; there are many insertions in the common fold

   • Species Moorella thermoacetica [TaxId:1525] [52660] (3 PDB entries)

6. GTPase domain of the signal recognition particle receptor FtsY [52666] (1 species)

   • Species Escherichia coli [TaxId:562] [52667] (1 PDB entry)

7. GTPase domain of the signal sequence recognition protein Ffh [52664] (2 species)

   1. Species Archaeon Acidianus ambivalens [TaxId:2283] [64023] (2 PDB entries)

   2. Species Thermus aquaticus [TaxId:271] [52665] (8 PDB entries)

8. Hypothetical protein YjiA, N-terminal domain [89671] (1 species)
   homologue of the cobalamin biosynthesis protein CobW

   • Species Escherichia coli [TaxId:562] [89672] (1 PDB entry)

9. Molybdopterin-guanine dinucleotide biosynthesis protein MobB [89673] (1 species)
   forms segment-swapped dimer

   • Species Escherichia coli [TaxId:562] [89674] (2 PDB entries)

10. Nitrogenase iron protein [52661] (2 species)

    1. Species Azotobacter vinelandii [TaxId:354] [52662] (11 PDB entries)

    2. Species Clostridium pasteurianum [TaxId:1501] [52663] (1 PDB entry)

More info for Family c.37.1.10: Nitrogenase iron protein-like

Timeline for Family c.37.1.10: Nitrogenase iron protein-like:

• Family c.37.1.10: Nitrogenase iron protein-like first appeared (with stable ids) in SCOP 1.55
  
• Family c.37.1.10: Nitrogenase iron protein-like appears in SCOP 1.63
  
• Family c.37.1.10: Nitrogenase iron protein-like appears in SCOP 1.67
  
• Family c.37.1.10: Nitrogenase iron protein-like appears in the current release, SCOPe 2.08