SCOPe 2.06: Protein: ADP-ribosylation factor

Lineage for Protein: ADP-ribosylation factor

Root: SCOPe 2.06
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
division into families based on beta-sheet topologies
Family c.37.1.8: G proteins [52592] (79 proteins)
core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest
Protein ADP-ribosylation factor [52614] (16 species)

Species:

Baker's yeast (Saccharomyces cerevisiae), ARF2 [TaxId:4932] [82401] (1 PDB entry)
- Domain for 1mr3:
  - Domain d1mr3f_: 1mr3 F: [79422]
    complexed with edo, eoh, g3d, gol, mg, pdo
Baker's yeast (Saccharomyces cerevisiae), ARL1 [TaxId:4932] [82402] (1 PDB entry)
- Domains for 1moz:
  1. Domain d1moza_: 1moz A: [79368]
    complexed with gdp
  2. Domain d1mozb_: 1moz B: [79369]
    complexed with gdp
Human (Homo sapiens) [TaxId:9606] [142220] (2 PDB entries)
1. Domain for 2b6h:
  - Domain d2b6ha1: 2b6h A:8-180 [127994]
    Other proteins in same PDB: d2b6ha2
    complexed with cl, gdp, so4, unx
2. Domains for 4dcn:
  1. Domain d4dcna_: 4dcn A: [251398]
    Other proteins in same PDB: d4dcnc_, d4dcnd_
    automated match to d1mr3f_
    complexed with gnp, mg
  2. Domain d4dcnb_: 4dcn B: [251399]
    Other proteins in same PDB: d4dcnc_, d4dcnd_
    automated match to d1mr3f_
    complexed with gnp, mg

Human (Homo sapiens), ARF1 [TaxId:9606] [52615] (14 PDB entries)
Uniprot P32889

Domains for 1hur:
1. Domain d1hura_: 1hur A: [32052]
  complexed with gdp, mg
2. Domain d1hurb_: 1hur B: [32053]
  complexed with gdp, mg
Domains for 1j2i:
1. Domain d1j2ia1: 1j2i A:18-181 [302526]
  Other proteins in same PDB: d1j2ia2, d1j2ib2
  automated match to d1o3ya_
  complexed with gtp, mg
2. Domain d1j2ib1: 1j2i B:18-181 [302528]
  Other proteins in same PDB: d1j2ia2, d1j2ib2
  automated match to d1o3ya_
  complexed with gtp, mg
Domain for 1j2j:
- Domain d1j2ja1: 1j2j A:18-180 [84016]
  Other proteins in same PDB: d1j2ja2, d1j2jb_
  complexed with gtp, iod, mg
Domains for 1o3y:
1. Domain d1o3ya1: 1o3y A:18-181 [86618]
  Other proteins in same PDB: d1o3ya2, d1o3yb2
  complexed with gtp, mg
2. Domain d1o3yb1: 1o3y B:18-181 [86619]
  Other proteins in same PDB: d1o3ya2, d1o3yb2
  complexed with gtp, mg
Domains for 1r8q:
1. Domain d1r8qa_: 1r8q A: [97243]
  Other proteins in same PDB: d1r8qe_, d1r8qf_
  complexed with a sec7 domain
  complexed with afb, g3d, mg, zn
2. Domain d1r8qb_: 1r8q B: [97244]
  Other proteins in same PDB: d1r8qe_, d1r8qf_
  complexed with a sec7 domain
  complexed with afb, g3d, mg, zn
Domain for 1r8r:
- Domain d1r8ra_: 1r8r A: [302986]
  Other proteins in same PDB: d1r8re_
  automated match to d1s9da_
  complexed with afb, gdp, mg
Domain for 1r8s:
- Domain d1r8sa_: 1r8s A: [97247]
  Other proteins in same PDB: d1r8se_
  complexed with a sec7 domain
  complexed with bme, fmt, gdp, so3, so4; mutant
Domain for 1re0:
- Domain d1re0a_: 1re0 A: [97317]
  Other proteins in same PDB: d1re0b1, d1re0b2
  complexed with a sec7 domain
  complexed with afb, cit, gdp, mg
Domain for 1s9d:
- Domain d1s9da_: 1s9d A: [98750]
  Other proteins in same PDB: d1s9de_
  complexed with a sec7 domain
  complexed with afb, gdp, mg
Domain for 1u81:
- Domain d1u81a_: 1u81 A: [113113]
  complexed with gdp, mg

Domains for 2j59:

Domain d2j59a2: 2j59 A:18-180 [138029]
Other proteins in same PDB: d2j59a3, d2j59b3, d2j59c3, d2j59d3, d2j59e3, d2j59f3, d2j59m1, d2j59n_, d2j59o_, d2j59p_, d2j59q_, d2j59r_
automated match to d1o3ya_
complexed with dio, edo, gtp, mg, so4

Domain d2j59b2: 2j59 B:18-180 [138030]
Other proteins in same PDB: d2j59a3, d2j59b3, d2j59c3, d2j59d3, d2j59e3, d2j59f3, d2j59m1, d2j59n_, d2j59o_, d2j59p_, d2j59q_, d2j59r_
automated match to d1o3ya_
complexed with dio, edo, gtp, mg, so4

Domain d2j59c2: 2j59 C:18-180 [138031]
Other proteins in same PDB: d2j59a3, d2j59b3, d2j59c3, d2j59d3, d2j59e3, d2j59f3, d2j59m1, d2j59n_, d2j59o_, d2j59p_, d2j59q_, d2j59r_
automated match to d1o3ya_
complexed with dio, edo, gtp, mg, so4

Domain d2j59d2: 2j59 D:18-180 [138032]
Other proteins in same PDB: d2j59a3, d2j59b3, d2j59c3, d2j59d3, d2j59e3, d2j59f3, d2j59m1, d2j59n_, d2j59o_, d2j59p_, d2j59q_, d2j59r_
automated match to d1o3ya_
complexed with dio, edo, gtp, mg, so4

Domain d2j59e2: 2j59 E:18-180 [138033]
Other proteins in same PDB: d2j59a3, d2j59b3, d2j59c3, d2j59d3, d2j59e3, d2j59f3, d2j59m1, d2j59n_, d2j59o_, d2j59p_, d2j59q_, d2j59r_
automated match to d1o3ya_
complexed with dio, edo, gtp, mg, so4

Domain d2j59f2: 2j59 F:18-180 [138034]
Other proteins in same PDB: d2j59a3, d2j59b3, d2j59c3, d2j59d3, d2j59e3, d2j59f3, d2j59m1, d2j59n_, d2j59o_, d2j59p_, d2j59q_, d2j59r_
automated match to d1o3ya_
complexed with dio, edo, gtp, mg, so4

Domains for 3n5c:
1. Domain d3n5ca_: 3n5c A: [213745]
  automated match to d1re0a_
  complexed with cl, gdp
2. Domain d3n5cb_: 3n5c B: [213746]
  automated match to d1re0a_
  complexed with cl, gdp
Domain for 3pcr:
- Domain d3pcrb_: 3pcr B: [214754]
  automated match to d1re0a_
  complexed with gtp, mg
Domain for 4kax:
- Domain d4kaxa1: 4kax A:14-173 [227592]
  Other proteins in same PDB: d4kaxa2, d4kaxa3, d4kaxb_
  automated match to d1o3ya_
  complexed with 4ip, cit, gol, gtp, k, mg

Human (Homo sapiens), ARF4 [TaxId:9606] [142217] (1 PDB entry)
Uniprot P18085 3-177
- Domains for 1z6x:
  1. Domain d1z6xa1: 1z6x A:4-178 [124571]
    complexed with gdp, mg
  2. Domain d1z6xb_: 1z6x B: [124572]
    automated match to d1hura_
    complexed with gdp, mg
Human (Homo sapiens), ARF6 [TaxId:9606] [52617] (5 PDB entries)
1. Domain for 1e0s:
  - Domain d1e0sa_: 1e0s A: [32057]
    complexed with bme, gdp, nh4
2. Domain for 2a5d:
  - Domain d2a5da_: 2a5d A: [126172]
    Other proteins in same PDB: d2a5db1
    automated match to d1e0sa_
    complexed with gol, gtp, mg, na
3. Domain for 2a5f:
  - Domain d2a5fa_: 2a5f A: [126173]
    Other proteins in same PDB: d2a5fb_
    automated match to d1e0sa_
    complexed with gol, gtp, mg, na, nad
4. Domain for 2a5g:
  - Domain d2a5ga1: 2a5g A:12-173 [126174]
    Other proteins in same PDB: d2a5gb_
    complexed with gtp, mg, na
5. Domains for 2j5x:
  1. Domain d2j5xa_: 2j5x A: [138072]
    automated match to d1e0sa_
    complexed with gsp, mg
  2. Domain d2j5xb_: 2j5x B: [138073]
    automated match to d1e0sa_
    complexed with gsp, mg
Human (Homo sapiens), ARL1 [TaxId:9606] [102364] (3 PDB entries)
1. Domains for 1r4a:
  1. Domain d1r4aa_: 1r4a A: [96986]
    Other proteins in same PDB: d1r4ae_, d1r4af_, d1r4ag_, d1r4ah_
    complexed with gnp, mg
  2. Domain d1r4ab_: 1r4a B: [96987]
    Other proteins in same PDB: d1r4ae_, d1r4af_, d1r4ag_, d1r4ah_
    complexed with gnp, mg
  3. Domain d1r4ac_: 1r4a C: [96988]
    Other proteins in same PDB: d1r4ae_, d1r4af_, d1r4ag_, d1r4ah_
    complexed with gnp, mg
  4. Domain d1r4ad_: 1r4a D: [96989]
    Other proteins in same PDB: d1r4ae_, d1r4af_, d1r4ag_, d1r4ah_
    complexed with gnp, mg
2. Domains for 1upt:
  1. Domain d1upta_: 1upt A: [99767]
    Other proteins in same PDB: d1uptb_, d1uptd_, d1uptf_, d1upth_
    complexed with gtp, mg
  2. Domain d1uptc_: 1upt C: [99769]
    Other proteins in same PDB: d1uptb_, d1uptd_, d1uptf_, d1upth_
    complexed with gtp, mg
  3. Domain d1upte_: 1upt E: [99771]
    Other proteins in same PDB: d1uptb_, d1uptd_, d1uptf_, d1upth_
    complexed with gtp, mg
  4. Domain d1uptg_: 1upt G: [99773]
    Other proteins in same PDB: d1uptb_, d1uptd_, d1uptf_, d1upth_
    complexed with gtp, mg
3. Domain for 5ee5:
  - Domain d5ee5b_: 5ee5 B: [319297]
    automated match to d1upta_
    complexed with act, cl, gol, gtp, mg, na
Human (Homo sapiens), ARL5A [TaxId:9606] [142218] (1 PDB entry)
Uniprot Q9Y689 2-178
- Domain for 1zj6:
  - Domain d1zj6a1: 1zj6 A:2-178 [125145]
    complexed with g3d, so4
Human (Homo sapiens), ARL5B [TaxId:9606] [142221] (1 PDB entry)
Uniprot Q96KC2 6-173
- Domain for 1yzg:
  - Domain d1yzga1: 1yzg A:6-173 [124276]
    complexed with gdp
Human (Homo sapiens), ARL8A [TaxId:9606] [142219] (1 PDB entry)
Uniprot Q96BM9 18-181
- Domain for 1zd9:
  - Domain d1zd9a1: 1zd9 A:17-181 [124938]
    Other proteins in same PDB: d1zd9a2
    complexed with gdp, mg
Human (Homo sapiens), ARL8B [TaxId:9606] [142222] (1 PDB entry)
Uniprot Q9NVJ2 18-182
- Domain for 2al7:
  - Domain d2al7a1: 2al7 A:17-181 [126972]
    Other proteins in same PDB: d2al7a2
    complexed with gdp, mg
Mouse (Mus musculus) [TaxId:10090] [225429] (3 PDB entries)
1. Domain for 3bh6:
  - Domain d3bh6a_: 3bh6 A: [208644]
    automated match to d1mr3f_
    complexed with gnp, mg
2. Domain for 3bh7:
  - Domain d3bh7a_: 3bh7 A: [155255]
    automated match to d1r4aa_
    complexed with alf, gdp, mg
3. Domains for 3vhx:
  1. Domain d3vhxa1: 3vhx A:13-173 [217820]
    Other proteins in same PDB: d3vhxa2, d3vhxc2, d3vhxe2, d3vhxg2
    automated match to d1upta_
    complexed with gol, gtp, mg
  2. Domain d3vhxc1: 3vhx C:13-173 [217821]
    Other proteins in same PDB: d3vhxa2, d3vhxc2, d3vhxe2, d3vhxg2
    automated match to d1upta_
    complexed with gol, gtp, mg
  3. Domain d3vhxe1: 3vhx E:13-173 [217822]
    Other proteins in same PDB: d3vhxa2, d3vhxc2, d3vhxe2, d3vhxg2
    automated match to d1upta_
    complexed with gol, gtp, mg
  4. Domain d3vhxg1: 3vhx G:13-173 [217823]
    Other proteins in same PDB: d3vhxa2, d3vhxc2, d3vhxe2, d3vhxg2
    automated match to d1upta_
    complexed with gol, gtp, mg
Mouse (Mus musculus), ARL2 [TaxId:10090] [75203] (5 PDB entries)
1. Domain for 1ksg:
  - Domain d1ksga1: 1ksg A:1-179 [72912]
    Other proteins in same PDB: d1ksga2, d1ksgb_
    complexed with GMP-PDE delta
    complexed with gtp, mg
2. Domain for 1ksh:
  - Domain d1ksha_: 1ksh A: [72914]
    Other proteins in same PDB: d1kshb_
    complexed with GMP-PDE delta
    complexed with gdp, mg, po4
3. Domain for 1ksj:
  - Domain d1ksja_: 1ksj A: [72916]
    Other proteins in same PDB: d1ksjb_
    complexed with GMP-PDE delta
    complexed with bme, gdp, gtp, mg, po4
4. Domains for 4gok:
  1. Domain d4goka_: 4gok A: [222059]
    automated match to d2rhda_
    complexed with gnp, mg
  2. Domain d4gokb_: 4gok B: [222060]
    automated match to d2rhda_
    complexed with gnp, mg
5. Domains for 4zi2:
  1. Domain d4zi2a1: 4zi2 A:3-182 [279400]
    Other proteins in same PDB: d4zi2a2
    automated match to d1ksga_
    complexed with gnp, mg
  2. Domain d4zi2b_: 4zi2 B: [279399]
    Other proteins in same PDB: d4zi2a2
    automated match to d1ksga_
    complexed with gnp, mg
Mouse (Mus musculus), ARL3 [TaxId:10090] [52618] (3 PDB entries)
1. Domain for 1fzq:
  - Domain d1fzqa_: 1fzq A: [32060]
    complexed with gdp, mes, nh4, so4
2. Domains for 4goj:
  1. Domain d4goja_: 4goj A: [194686]
    automated match to d1fzqa_
    complexed with gnp, mg
  2. Domain d4gojb_: 4goj B: [202280]
    automated match to d4goja_
    complexed with gnp, mg
3. Domains for 4zi3:
  1. Domain d4zi3a1: 4zi3 A:3-182 [312333]
    Other proteins in same PDB: d4zi3a2
    automated match to d1fzqa_
    complexed with gnp, mg
  2. Domain d4zi3b_: 4zi3 B: [312323]
    Other proteins in same PDB: d4zi3a2
    automated match to d1fzqa_
    complexed with gnp, mg
Norway rat (Rattus norvegicus), ARF1 [TaxId:10116] [52616] (2 PDB entries)
1. Domain for 1rrf:
  - Domain d1rrfa_: 1rrf A: [32056]
    complexed with gdp, mg
2. Domains for 1rrg:
  1. Domain d1rrga_: 1rrg A: [32054]
    complexed with gdp, mg
  2. Domain d1rrgb_: 1rrg B: [32055]
    complexed with gdp, mg
Thale cress (Arabidopsis thaliana) [TaxId:3702] [189615] (1 PDB entry)
- Domains for 3aq4:
  1. Domain d3aq4a_: 3aq4 A: [172300]
    automated match to d1hura_
    complexed with gdp, mg
  2. Domain d3aq4b_: 3aq4 B: [172301]
    automated match to d1hura_
    complexed with gdp, mg

More info for Protein ADP-ribosylation factor from c.37.1.8: G proteins

Timeline for Protein ADP-ribosylation factor from c.37.1.8: G proteins:

Protein ADP-ribosylation factor from c.37.1.8: G proteins first appeared (with stable ids) in SCOP 1.55
Protein ADP-ribosylation factor from c.37.1.8: G proteins appears in SCOPe 2.05
Protein ADP-ribosylation factor from c.37.1.8: G proteins appears in SCOPe 2.07
Protein ADP-ribosylation factor from c.37.1.8: G proteins appears in the current release, SCOPe 2.08