Lineage for Protein: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2109203Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2109204Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families) (S)
    division into families based on beta-sheet topologies
  5. 2110089Family c.37.1.7: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain [52589] (1 protein)
    automatically mapped to Pfam PF01591
  6. 2110090Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain [52590] (2 species)
    bifunctional enzyme

Species:

  1. 2110091Human (Homo sapiens) [TaxId:9606] [82398] (1 PDB entry)
  2. 2110094Norway rat (Rattus norvegicus) [TaxId:10116] [52591] (3 PDB entries)
    1. Domain for 1bif:
    2. Domains for 2bif:
      1. 2110097Domain d2bifa1: 2bif A:37-249 [31963]
        Other proteins in same PDB: d2bifa2, d2bifb2
        complexed with anp, bog, f6p, mg, po4, sin; mutant
      2. 2110098Domain d2bifb1: 2bif B:37-249 [31964]
        Other proteins in same PDB: d2bifa2, d2bifb2
        complexed with anp, bog, f6p, mg, po4, sin; mutant
    3. Domain for 3bif:

More info for Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain from c.37.1.7: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain

Timeline for Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain from c.37.1.7: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain:

  • Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain from c.37.1.7: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain first appeared (with stable ids) in SCOP 1.55
  • Protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain from c.37.1.7: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain appears in SCOPe 2.05