SCOPe 2.01: Family c.37.1.5: PAPS sulfotransferase

Lineage for Family c.37.1.5: PAPS sulfotransferase

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.5: PAPS sulfotransferase [52575] (15 proteins)
   Pfam PF00685
   similar to the nucleotide/nucleoside kinases but transfer sulphate group

Proteins:

1. Aryl sulfotransferase sult1a [102346] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [102347] (2 PDB entries)

2. Aryl sulfotransferase sult1a3 [52580] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [52581] (1 PDB entry)

3. Cholesterol sulfotransferase sult2b1b [102350] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [102351] (3 PDB entries)
     cytosolic enzyme

4. Estrogen sulfotransferase (STE, sult1e1) [52576] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [75198] (2 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [52577] (3 PDB entries)

5. Heparan sulfate 3-O-sulfotransferase [102354] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [102355] (1 PDB entry)
     Uniprot O35310 48-311

6. Heparan sulfate glucosamine 3-O-sulfotransferase 3 [110532] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [110533] (2 PDB entries)
     Uniprot Q9Y663 139-406 # isoform 3A1; 100% sequence identity to isoform 3B1 domain (Uniprot Q9Y662 133-390)

7. Heparan sulfate N-deacetylase/N-sulfotransferase domain [52582] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [52583] (1 PDB entry)

8. Hydroxysteroid sulfotransferase sult2a1 [52578] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [52579] (5 PDB entries)

9. Pregnenolone sulfotransferase sult2b1a [102348] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [102349] (1 PDB entry)
     cytosolic enzyme

10. Putative steroid sulfotransferase rarO47 [102352] (1 species)

    • Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [102353] (1 PDB entry)

11. Retinol dehydratase [64015] (1 species)

    • Species Fall armyworm (Spodoptera frugiperda) [TaxId:7108] [64016] (2 PDB entries)

12. Stf0 sulfotransferase [110530] (1 species)

    • Species Mycobacterium smegmatis [TaxId:1772] [110531] (1 PDB entry)
      Uniprot P84151

13. Sulfotransferase Sult1c2 [159556] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [159557] (1 PDB entry)
      Uniprot O00338 12-296

14. Thyroid hormone sulfotransferase Sult1b1 [117530] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [117531] (1 PDB entry)
      Uniprot O43704

15. automated matches [190189] (4 species)
    not a true protein

    1. Species Fall armyworm (Spodoptera frugiperda) [TaxId:7108] [188114] (3 PDB entries)

    2. Species Human (Homo sapiens) [TaxId:9606] [186928] (7 PDB entries)

    3. Species Mouse (Mus musculus) [TaxId:10090] [188670] (7 PDB entries)

    4. Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [187179] (1 PDB entry)

More info for Family c.37.1.5: PAPS sulfotransferase

Timeline for Family c.37.1.5: PAPS sulfotransferase:

• Family c.37.1.5: PAPS sulfotransferase first appeared (with stable ids) in SCOP 1.55
  
• Family c.37.1.5: PAPS sulfotransferase appears in SCOP 1.75
  
• Family c.37.1.5: PAPS sulfotransferase appears in SCOPe 2.02
  
• Family c.37.1.5: PAPS sulfotransferase appears in the current release, SCOPe 2.08