SCOPe 2.05: Protein: Thymidylate kinase

Lineage for Protein: Thymidylate kinase

Root: SCOPe 2.05
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
division into families based on beta-sheet topologies
Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 proteins)
parallel beta-sheet of 5 strands, order 23145
Protein Thymidylate kinase [52563] (4 species)

Species:

Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52564] (3 PDB entries)
1. Domains for 1tmk:
  1. Domain d1tmka_: 1tmk A: [31918]
    complexed with so4, tmp
  2. Domain d1tmkb_: 1tmk B: [31919]
    complexed with so4, tmp
2. Domains for 2tmk:
  1. Domain d2tmka_: 2tmk A: [31928]
    complexed with atm, so4
  2. Domain d2tmkb_: 2tmk B: [31929]
    complexed with atm, so4
3. Domains for 3tmk:
  1. Domain d3tmka_: 3tmk A: [31920]
    complexed with t5a
  2. Domain d3tmkb_: 3tmk B: [31921]
    complexed with t5a
  3. Domain d3tmkc_: 3tmk C: [31922]
    complexed with t5a
  4. Domain d3tmkd_: 3tmk D: [31923]
    complexed with t5a
  5. Domain d3tmke_: 3tmk E: [31924]
    complexed with t5a
  6. Domain d3tmkf_: 3tmk F: [31925]
    complexed with t5a
  7. Domain d3tmkg_: 3tmk G: [31926]
    complexed with t5a
  8. Domain d3tmkh_: 3tmk H: [31927]
    complexed with t5a
Escherichia coli [TaxId:562] [52565] (2 PDB entries)
1. Domain for 4tmk:
  - Domain d4tmka_: 4tmk A: [31930]
    complexed with t5a
2. Domain for 5tmp:
  - Domain d5tmpa_: 5tmp A: [31931]
    complexed with z5a
Human (Homo sapiens) [TaxId:9606] [64010] (20 PDB entries)
1. Domain for 1e2d:
  - Domain d1e2da_: 1e2d A: [59162]
    complexed with adp, mg, tmp
2. Domain for 1e2e:
  - Domain d1e2ea_: 1e2e A: [59163]
    complexed with adp, af3, mg, tmp
3. Domain for 1e2f:
  - Domain d1e2fa_: 1e2f A: [59164]
    complexed with adp, anp, mg, tmp
4. Domain for 1e2g:
  - Domain d1e2ga_: 1e2g A: [59165]
    complexed with adp, mg, tmp, tyd
5. Domain for 1e2q:
  - Domain d1e2qa_: 1e2q A: [59172]
    complexed with atp, mg, tmp
6. Domain for 1e98:
  - Domain d1e98a_: 1e98 A: [64804]
    complexed with adp, atm, mg
7. Domain for 1e99:
  - Domain d1e99a_: 1e99 A: [64805]
    complexed with adp, atm, mg
8. Domain for 1e9a:
  - Domain d1e9aa_: 1e9a A: [64806]
    complexed with mg, z5a
9. Domain for 1e9b:
  - Domain d1e9ba_: 1e9b A: [64807]
    complexed with adp, anp, atm, mg
10. Domain for 1e9c:
  - Domain d1e9ca_: 1e9c A: [64808]
    complexed with adp, anp, mg, tmp; mutant
11. Domain for 1e9d:
  - Domain d1e9da_: 1e9d A: [64809]
    complexed with adp, atm, mg; mutant
12. Domain for 1e9e:
  - Domain d1e9ea_: 1e9e A: [64810]
    complexed with adp, mg, tmp; mutant
13. Domain for 1e9f:
  - Domain d1e9fa_: 1e9f A: [64811]
    complexed with adp, mg, tmp; mutant
14. Domain for 1nmx:
  - Domain d1nmxa_: 1nmx A: [85882]
    complexed with adp, fdm, mg
15. Domain for 1nmy:
  - Domain d1nmya_: 1nmy A: [85883]
    complexed with adp, anp, fdm, mg
16. Domain for 1nmz:
  - Domain d1nmza_: 1nmz A: [85884]
    complexed with anp, mg, nym
17. Domain for 1nn0:
  - Domain d1nn0a_: 1nn0 A: [85885]
    complexed with 2dt, adp, mg
18. Domain for 1nn1:
  - Domain d1nn1a_: 1nn1 A: [85886]
    complexed with 2dt, anp, mg
19. Domain for 1nn3:
  - Domain d1nn3a_: 1nn3 A: [85887]
    complexed with 2dt, adp, mg
20. Domain for 1nn5:
  - Domain d1nn5a_: 1nn5 A: [85892]
    complexed with 2dt, anp, mg
Mycobacterium tuberculosis [TaxId:1773] [69482] (9 PDB entries)
1. Domain for 1g3u:
  - Domain d1g3ua_: 1g3u A: [65132]
    complexed with mg, so4, tmp
2. Domain for 1gsi:
  - Domain d1gsia_: 1gsi A: [70396]
    complexed with act, mg, so4, tmp
3. Domains for 1gtv:
  1. Domain d1gtva_: 1gtv A: [70537]
    complexed with act, mg, so4, tmp, tyd
  2. Domain d1gtvb_: 1gtv B: [70538]
    complexed with act, mg, so4, tmp, tyd
4. Domain for 1mrn:
  - Domain d1mrna_: 1mrn A: [79423]
    complexed with mg, so4, t5a
5. Domain for 1mrs:
  - Domain d1mrsa_: 1mrs A: [79424]
    complexed with 5hu, mg, so4
6. Domain for 1n5i:
  - Domain d1n5ia_: 1n5i A: [85330]
    complexed with atp, flc, so4, tmp
7. Domain for 1n5j:
  - Domain d1n5ja_: 1n5j A: [85331]
    complexed with mg, so4, ttp, tyd
8. Domains for 1n5k:
  1. Domain d1n5ka_: 1n5k A: [85332]
    complexed with act, mg, tmp
  2. Domain d1n5kb_: 1n5k B: [85333]
    complexed with act, mg, tmp
9. Domains for 1n5l:
  1. Domain d1n5la_: 1n5l A: [85334]
    complexed with act, dpo, mg, tmp, tyd
  2. Domain d1n5lb_: 1n5l B: [85335]
    complexed with act, dpo, mg, tmp, tyd

More info for Protein Thymidylate kinase from c.37.1.1: Nucleotide and nucleoside kinases

Timeline for Protein Thymidylate kinase from c.37.1.1: Nucleotide and nucleoside kinases:

Protein Thymidylate kinase from c.37.1.1: Nucleotide and nucleoside kinases first appeared (with stable ids) in SCOP 1.55
Protein Thymidylate kinase from c.37.1.1: Nucleotide and nucleoside kinases appears in SCOPe 2.04
Protein Thymidylate kinase from c.37.1.1: Nucleotide and nucleoside kinases appears in SCOPe 2.06
Protein Thymidylate kinase from c.37.1.1: Nucleotide and nucleoside kinases appears in the current release, SCOPe 2.08