Lineage for Protein: Thymidine kinase

  1. Root: SCOP 1.75
  2. 814173Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 829350Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 829351Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (24 families) (S)
    division into families based on beta-sheet topologies
  5. 829352Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (20 proteins)
    parallel beta-sheet of 5 strands, order 23145
  6. 829617Protein Thymidine kinase [52552] (3 species)
    contains insert all-alpha subdomain, res. 251-322

Species:

  1. 829618Equine herpesvirus type 4 [TaxId:10331] [102340] (4 PDB entries)
    1. Domains for 1p6x:
      1. 829619Domain d1p6xa_: 1p6x A: [94195]
      2. 829620Domain d1p6xb_: 1p6x B: [94196]
        complexed with so4, thm
    2. Domains for 1p72:
      1. 829621Domain d1p72a_: 1p72 A: [94200]
      2. 829622Domain d1p72b_: 1p72 B: [94201]
        complexed with adp, so4, thm
    3. Domains for 1p73:
      1. 829623Domain d1p73a_: 1p73 A: [94202]
      2. 829624Domain d1p73b_: 1p73 B: [94203]
      3. 829625Domain d1p73c_: 1p73 C: [94204]
      4. 829626Domain d1p73d_: 1p73 D: [94205]
        complexed with 4ta, so4
    4. Domains for 1p75:
      1. 829627Domain d1p75a_: 1p75 A: [94210]
      2. 829628Domain d1p75b_: 1p75 B: [94211]
      3. 829629Domain d1p75c_: 1p75 C: [94212]
      4. 829630Domain d1p75d_: 1p75 D: [94213]
        complexed with so4, t5a
  2. 829631Herpes simplex virus type 1, different strains [TaxId:10298] [52553] (22 PDB entries)
    Uniprot P03176 46-375
    1. Domains for 1e2h:
      1. 829636Domain d1e2ha_: 1e2h A: [31856]
      2. 829637Domain d1e2hb_: 1e2h B: [31857]
        complexed with so4
    2. Domains for 1e2i:
      1. 829638Domain d1e2ia_: 1e2i A: [31858]
      2. 829639Domain d1e2ib_: 1e2i B: [31859]
        complexed with aps, arp, so4
    3. Domains for 1e2j:
      1. 829654Domain d1e2ja_: 1e2j A: [31874]
      2. 829655Domain d1e2jb_: 1e2j B: [31875]
        complexed with so4, thm; mutant
    4. Domains for 1e2k:
      1. 829632Domain d1e2ka_: 1e2k A: [31854]
      2. 829633Domain d1e2kb_: 1e2k B: [31855]
        complexed with so4, tmc; mutant
    5. Domains for 1e2l:
      1. 829656Domain d1e2la_: 1e2l A: [31872]
      2. 829657Domain d1e2lb_: 1e2l B: [31873]
        complexed with so4, tmc; mutant
    6. Domains for 1e2m:
      1. 829642Domain d1e2ma_: 1e2m A: [59166]
      2. 829643Domain d1e2mb_: 1e2m B: [59167]
        complexed with hpt, so4
    7. Domains for 1e2n:
      1. 829640Domain d1e2na_: 1e2n A: [59168]
      2. 829641Domain d1e2nb_: 1e2n B: [59169]
        complexed with rca, so4
    8. Domains for 1e2p:
      1. 829652Domain d1e2pa_: 1e2p A: [59170]
      2. 829653Domain d1e2pb_: 1e2p B: [59171]
        complexed with ccv, so4
    9. Domains for 1ki2:
      1. 829662Domain d1ki2a_: 1ki2 A: [31870]
      2. 829663Domain d1ki2b_: 1ki2 B: [31871]
        complexed with ga2, so4
    10. Domains for 1ki3:
      1. 829670Domain d1ki3a_: 1ki3 A: [31880]
      2. 829671Domain d1ki3b_: 1ki3 B: [31881]
        complexed with pe2, so4
    11. Domains for 1ki4:
      1. 829667Domain d1ki4a_: 1ki4 A: [31878]
      2. 829668Domain d1ki4b_: 1ki4 B: [31879]
        complexed with btd, so4
    12. Domains for 1ki6:
      1. 829664Domain d1ki6a_: 1ki6 A: [31876]
      2. 829665Domain d1ki6b_: 1ki6 B: [31877]
        complexed with ahu, so4
    13. Domains for 1ki7:
      1. 829660Domain d1ki7a_: 1ki7 A: [31868]
      2. 829661Domain d1ki7b_: 1ki7 B: [31869]
        complexed with id2, so4
    14. Domains for 1ki8:
      1. 829658Domain d1ki8a_: 1ki8 A: [31866]
      2. 829659Domain d1ki8b_: 1ki8 B: [31867]
        complexed with bvd, so4
    15. Domains for 1kim:
      1. 829648Domain d1kima_: 1kim A: [31864]
      2. 829649Domain d1kimb_: 1kim B: [31865]
        complexed with so4, thm
    16. Domains for 1of1:
      1. 829634Domain d1of1a_: 1of1 A: [103924]
      2. 829635Domain d1of1b_: 1of1 B: [103925]
        complexed with sct, so4
    17. Domains for 1p7c:
      1. 829650Domain d1p7ca_: 1p7c A: [94217]
      2. 829651Domain d1p7cb_: 1p7c B: [94218]
        complexed with so4, t5a, thm
    18. Domains for 1qhi:
      1. 829644Domain d1qhia_: 1qhi A: [31860]
      2. 829645Domain d1qhib_: 1qhi B: [31861]
        complexed with bpg, so4
    19. Domain for 1vtk:
    20. Domains for 2ki5:
      1. 829646Domain d2ki5a_: 2ki5 A: [31862]
      2. 829647Domain d2ki5b_: 2ki5 B: [31863]
        complexed with ac2, so4
    21. Domain for 2vtk:
    22. Domain for 3vtk:
  3. 829673Varicella-zoster virus [TaxId:10335] [89659] (1 PDB entry)

More info for Protein Thymidine kinase from c.37.1.1: Nucleotide and nucleoside kinases

Timeline for Protein Thymidine kinase from c.37.1.1: Nucleotide and nucleoside kinases: