Lineage for Family c.37.1.1: Nucleotide and nucleoside kinases

  1. Root: SCOP 1.69
  2. 473232Class c: Alpha and beta proteins (a/b) [51349] (136 folds)
  3. 483669Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 483670Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (22 families) (S)
    division into families based on beta-sheet topologies
  5. 483671Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (17 proteins)
    parallel beta-sheet of 5 strands, order 23145

Proteins:

  1. 483672Adenylate kinase [52554] (13 species)
    1. 483673Species Archaeon Methanococcus thermolithotrophicus [TaxId:2186] [89661] (1 PDB entry)
    2. 483677Species Archaeon Methanococcus voltae [TaxId:2188] [89660] (1 PDB entry)
    3. 483681Species Archaeon Sulfolobus acidocaldarius [TaxId:2285] [52556] (1 PDB entry)
    4. 483688Species Bacillus globisporus [TaxId:1459] [102342] (1 PDB entry)
      contains a zinc-finger subdomain, residues 126-160
    5. 483690Species Bacillus stearothermophilus [TaxId:1422] [52562] (3 PDB entries)
      contains a zinc-finger subdomain, residues 126-160
    6. 483694Species Bacillus subtilis [TaxId:1423] [102341] (1 PDB entry)
      contains a zinc-finger subdomain, residues 126-160
    7. 483696Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52559] (4 PDB entries)
      contains a rudiment "zinc-finger" subdomain, residue 131-168
    8. 483702Species Cow (Bos taurus), mitochondrial izozyme-2 [TaxId:9913] [52558] (2 PDB entries)
      contains a rudiment "zinc-finger" subdomain, residue 147-176
    9. 483705Species Cow (Bos taurus), mitochondrial izozyme-3 [TaxId:9913] [52557] (1 PDB entry)
      contains a rudiment "zinc-finger" subdomain, residue 125-161
    10. 483708Species Escherichia coli [TaxId:562] [52560] (6 PDB entries)
      contains a rudiment "zinc-finger" subdomain, residue 122-156
    11. 483721Species Maize (Zea mays) [TaxId:4577] [52561] (1 PDB entry)
    12. 483724Species Mycobacterium tuberculosis [TaxId:1773] [102343] (1 PDB entry)
      contains no zinc finger-like insertion
    13. 483726Species Pig (Sus scrofa) [TaxId:9823] [52555] (1 PDB entry)
  2. 483728CMP kinase [52548] (2 species)
    1. 483729Species Escherichia coli [TaxId:562] [52549] (6 PDB entries)
    2. 483740Species Streptococcus pneumoniae [TaxId:1313] [110525] (1 PDB entry)
  3. 483742Deoxycytidine kinase [89657] (1 species)
  4. 483749Deoxyguanosine kinase [69480] (1 species)
  5. 483759Deoxynucleoside monophosphate kinase [52546] (1 species)
    contains insert 4-helical bundle subdomain, residues 35-145
  6. 483765Deoxyribonucleoside kinase [69478] (1 species)
  7. 483781Dephospho-CoA kinase [75187] (3 species)
    1. 483782Species Escherichia coli [TaxId:562] [82394] (5 PDB entries)
    2. 483798Species Haemophilus influenzae [TaxId:727] [75188] (1 PDB entry)
    3. 483800Species Thermus thermophilus [TaxId:274] [102344] (1 PDB entry)
      TT1252
  8. 483804Guanylate kinase [52542] (4 species)
    1. 483805Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52543] (3 PDB entries)
    2. 483810Species Escherichia coli [TaxId:562] [102338] (1 PDB entry)
    3. 483813Species Mouse (Mus musculus) [TaxId:10090] [82393] (1 PDB entry)
    4. 483815Species Mycobacterium tuberculosis [TaxId:1773] [102339] (1 PDB entry)
      Rv1389
  9. 483817Guanylate kinase-like domain of Cask [69474] (1 species)
  10. 483820Guanylate kinase-like domain of Psd-95 [69476] (1 species)
  11. 483826Guanylate kinase-like domain of the L-type calcium channel [110527] (2 species)
    1. 483827Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [110528] (4 PDB entries)
    2. 483832Species Rat (Rattus norvegicus) [TaxId:10116] [110529] (3 PDB entries)
  12. 483839Polynucleotide kinase, kinase domain [75191] (1 species)
  13. 483846Thymidine kinase [52552] (3 species)
    contains insert all-alpha subdomain, res. 251-322
    1. 483847Species Equine herpesvirus type 4 [TaxId:10331] [102340] (4 PDB entries)
    2. 483860Species Herpes simplex virus type 1, different strains [TaxId:10298] [52553] (22 PDB entries)
    3. 483902Species Varicella-zoster virus [TaxId:10335] [89659] (1 PDB entry)
  14. 483907Thymidylate kinase [52563] (4 species)
    1. 483908Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52564] (3 PDB entries)
    2. 483921Species Escherichia coli [TaxId:562] [52565] (2 PDB entries)
    3. 483924Species Human (Homo sapiens) [TaxId:9606] [64010] (20 PDB entries)
    4. 483945Species Mycobacterium tuberculosis [TaxId:1773] [69482] (9 PDB entries)
  15. 483958Transcriptional regulator NadR, ribosylnicotinamide kinase domain [75189] (1 species)
  16. 483961UMP/CMP kinase [52550] (2 species)
    1. 483962Species Dictyostelium discoideum [TaxId:44689] [52551] (6 PDB entries)
    2. 483969Species Human (Homo sapiens) [TaxId:9606] [110526] (1 PDB entry)
  17. 483971Uridylate kinase [52544] (1 species)

More info for Family c.37.1.1: Nucleotide and nucleoside kinases

Timeline for Family c.37.1.1: Nucleotide and nucleoside kinases: