SCOP 1.67: Family c.37.1.1: Nucleotide and nucleoside kinases

Lineage for Family c.37.1.1: Nucleotide and nucleoside kinases

1. Root: SCOP 1.67

2. Class c: Alpha and beta proteins (a/b) [51349] (130 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (22 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (16 proteins)
   parallel beta-sheet of 5 strands, order 23145

Proteins:

1. Adenylate kinase [52554] (13 species)

   1. Species Archaeon Methanococcus thermolithotrophicus [TaxId:2186] [89661] (1 PDB entry)

   2. Species Archaeon Methanococcus voltae [TaxId:2188] [89660] (1 PDB entry)

   3. Species Archaeon Sulfolobus acidocaldarius [TaxId:2285] [52556] (1 PDB entry)

   4. Species Bacillus globisporus [TaxId:1459] [102342] (1 PDB entry)
      contains a zinc-finger subdomain, residues 126-160

   5. Species Bacillus stearothermophilus [TaxId:1422] [52562] (3 PDB entries)
      contains a zinc-finger subdomain, residues 126-160

   6. Species Bacillus subtilis [TaxId:1423] [102341] (1 PDB entry)
      contains a zinc-finger subdomain, residues 126-160

   7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52559] (4 PDB entries)
      contains a rudiment "zinc-finger" subdomain, residue 131-168

   8. Species Cow (Bos taurus), mitochondrial izozyme-2 [TaxId:9913] [52558] (2 PDB entries)
      contains a rudiment "zinc-finger" subdomain, residue 147-176

   9. Species Cow (Bos taurus), mitochondrial izozyme-3 [TaxId:9913] [52557] (1 PDB entry)
      contains a rudiment "zinc-finger" subdomain, residue 125-161

   10. Species Escherichia coli [TaxId:562] [52560] (6 PDB entries)
       contains a rudiment "zinc-finger" subdomain, residue 122-156

   11. Species Maize (Zea mays) [TaxId:4577] [52561] (1 PDB entry)

   12. Species Mycobacterium tuberculosis [TaxId:1773] [102343] (1 PDB entry)
       contains no zinc finger-like insertion

   13. Species Pig (Sus scrofa) [TaxId:9823] [52555] (1 PDB entry)

2. CMP kinase [52548] (1 species)

   • Species Escherichia coli [TaxId:562] [52549] (6 PDB entries)

3. Deoxycytidine kinase [89657] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [89658] (4 PDB entries)

4. Deoxyguanosine kinase [69480] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [69481] (1 PDB entry)

5. Deoxynucleoside monophosphate kinase [52546] (1 species)
   contains insert 4-helical bundle subdomain, residues 35-145

   • Species Bacteriophage T4 [TaxId:10665] [52547] (2 PDB entries)

6. Deoxyribonucleoside kinase [69478] (1 species)

   • Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [69479] (3 PDB entries)

7. Dephospho-CoA kinase [75187] (3 species)

   1. Species Escherichia coli [TaxId:562] [82394] (5 PDB entries)

   2. Species Haemophilus influenzae [TaxId:727] [75188] (1 PDB entry)

   3. Species Thermus thermophilus [TaxId:274] [102344] (1 PDB entry)
      TT1252

8. Guanylate kinase [52542] (4 species)

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52543] (3 PDB entries)

   2. Species Escherichia coli [TaxId:562] [102338] (1 PDB entry)

   3. Species Mouse (Mus musculus) [TaxId:10090] [82393] (1 PDB entry)

   4. Species Mycobacterium tuberculosis [TaxId:1773] [102339] (1 PDB entry)
      Rv1389

9. Guanylate kinase-like domain of Cask [69474] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [69475] (1 PDB entry)

10. Guanylate kinase-like domain of Psd-95 [69476] (1 species)

    • Species Rat (Rattus norvegicus) [TaxId:10116] [69477] (3 PDB entries)

11. Polynucleotide kinase, kinase domain [75191] (1 species)

    • Species Bacteriophage T4 [TaxId:10665] [75192] (5 PDB entries)

12. Thymidine kinase [52552] (3 species)
    contains insert all-alpha subdomain, res. 251-322

    1. Species Equine herpesvirus type 4 [TaxId:10331] [102340] (4 PDB entries)

    2. Species Herpes simplex virus type 1, different strains [TaxId:10298] [52553] (21 PDB entries)

    3. Species Varicella-zoster virus [TaxId:10335] [89659] (1 PDB entry)

13. Thymidylate kinase [52563] (4 species)

    1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52564] (3 PDB entries)

    2. Species Escherichia coli [TaxId:562] [52565] (2 PDB entries)

    3. Species Human (Homo sapiens) [TaxId:9606] [64010] (20 PDB entries)

    4. Species Mycobacterium tuberculosis [TaxId:1773] [69482] (9 PDB entries)

14. Transcriptional regulator NadR, ribosylnicotinamide kinase domain [75189] (1 species)

    • Species Haemophilus influenzae [TaxId:727] [75190] (1 PDB entry)

15. UMP/CMP kinase [52550] (1 species)

    • Species Dictyostelium discoideum [TaxId:44689] [52551] (6 PDB entries)

16. Uridylate kinase [52544] (1 species)

    • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52545] (2 PDB entries)

More info for Family c.37.1.1: Nucleotide and nucleoside kinases

Timeline for Family c.37.1.1: Nucleotide and nucleoside kinases:

• Family c.37.1.1: Nucleotide and nucleoside kinases first appeared (with stable ids) in SCOP 1.55
  
• Family c.37.1.1: Nucleotide and nucleoside kinases appears in SCOP 1.65
  
• Family c.37.1.1: Nucleotide and nucleoside kinases appears in SCOP 1.69
  
• Family c.37.1.1: Nucleotide and nucleoside kinases appears in the current release, SCOPe 2.08