SCOPe: Structural Classification of Proteins — extended. Release 2.03 (October 2013)
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Lineage for Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases

  1. Root: SCOPe 2.03
  2. 1332976Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1356875Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 1356876Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families) (S)
    division into families based on beta-sheet topologies

Families:

  1. 1356877c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 protein domains)
    parallel beta-sheet of 5 strands, order 23145
  2. 1357346c.37.1.2: Shikimate kinase (AroK) [52566] (2 protein domains)
    similar to the nucleotide/nucleoside kinases but acts on different substrate
    automatically mapped to Pfam PF01202
  3. 1357392c.37.1.3: Chloramphenicol phosphotransferase [52569] (1 protein)
    similar to the nucleotide/nucleoside kinases but acts on different substrate
    automatically mapped to Pfam PF07931
  4. 1357401c.37.1.4: Adenosine-5'phosphosulfate kinase (APS kinase) [52572] (2 protein domains)
    automatically mapped to Pfam PF01583
  5. 1357432c.37.1.5: PAPS sulfotransferase [52575] (15 protein domains)
    Pfam PF00685
    similar to the nucleotide/nucleoside kinases but transfer sulphate group
  6. 1357548c.37.1.6: Phosphoribulokinase/pantothenate kinase [52584] (6 protein domains)
  7. 1357606c.37.1.7: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain [52589] (1 protein)
    automatically mapped to Pfam PF01591
  8. 1357616c.37.1.8: G proteins [52592] (79 protein domains)
    core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest
  9. 1358805c.37.1.9: Motor proteins [52641] (5 protein domains)
  10. 1359015c.37.1.10: Nitrogenase iron protein-like [52652] (16 protein domains)
    core: parallel beta-sheet of 7 strands; order 3241567
  11. 1359307c.37.1.11: RecA protein-like (ATPase-domain) [52670] (18 protein domains)
    core: mixed beta-sheet of 8 strands, order 32451678; strand 7 is antiparallel to the rest
  12. 1359790c.37.1.12: ABC transporter ATPase domain-like [52686] (24 protein domains)
    there are two additional subdomains inserted into the central core that has a RecA-like topology
  13. 1360043c.37.1.14: RNA helicase [52724] (4 protein domains)
    duplication: consists of two similar domains, one binds NTP and the other binds RNA; also contains an all-alpha subdomain in the C-terminal extension
  14. 1360105c.37.1.15: ATP sulfurylase C-terminal domain [64011] (1 protein)
  15. 1360128c.37.1.16: Helicase-like "domain" of reverse gyrase [69496] (1 protein)
  16. 1360137c.37.1.17: Gluconate kinase [75195] (1 protein)
    similar to the nucleotide/nucleoside kinases
    automatically mapped to Pfam PF01202
  17. 1360152c.37.1.18: YjeE-like [75213] (1 protein)
    mixed beta-sheet; order 234156(0), strands 2 and 6 are antiparallel to the rest
    automatically mapped to Pfam PF02367
  18. 1360161c.37.1.19: Tandem AAA-ATPase domain [81268] (24 protein domains)
    duplication: tandem repeat of two RecA-like (AAA) domains
  19. 1360371c.37.1.20: Extended AAA-ATPase domain [81269] (29 protein domains)
    fold is similar to that of RecA, but lacks the last two strands, followed by a family-specific Arg-finger domain
  20. 1360679c.37.1.21: Plasmid maintenance system epsilon/zeta, toxin zeta subunit [82395] (2 protein domains)
    similar to the nucleotide/nucleoside kinases; extra N- and C-terminal structures
  21. 1360688c.37.1.22: Bacterial cell division inhibitor SulA [89678] (1 protein)
    homologous to RecA but lacks its P-loop motif; the fold is C-terminally truncated; 5-stranded parallel beta-sheet, order: 15423
  22. 1360697c.37.1.23: DNA helicase UvsW [102396] (1 protein)
    contains extra N-terminal alpha+beta subdomain
  23. 1360702c.37.1.24: Type II thymidine kinase [117558] (2 protein domains)
    N-terminal part of Pfam PF00265; parallel beta-sheet of 6 strands, order 324516; topological similarity to the RecA-like proteins, especially CobA (52684)
  24. 1360729c.37.1.25: Atu3015-like [142332] (2 protein domains)
    unknown function; similar to the nucleotide/nucleoside kinases
  25. 1360736c.37.1.0: automated matches [191323] (1 protein)
    not a true family

More info for Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases

Timeline for Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases:


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