SCOP 1.63: Family c.36.1.1: Pyruvate oxidase and decarboxylase THDP-binding domains

Lineage for Family c.36.1.1: Pyruvate oxidase and decarboxylase THDP-binding domains

1. Root: SCOP 1.63

2. Class c: Alpha and beta proteins (a/b) [51349] (117 folds)

3. Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465

4. Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (4 families)
   both pyridine (Pyr)- and pyrophosphate (PP)-binding modules have this fold
   conserved core consists of two Pyr and two PP-modules and binds two coenzyme molecules

5. Family c.36.1.1: Pyruvate oxidase and decarboxylase THDP-binding domains [52519] (4 proteins)
   the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpa/beta domain of Rossmann-like topology

Proteins:

1. Acetohydroxyacid synthase catalytic subunit [69470] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [69471] (2 PDB entries)

2. Benzoylformate decarboxylase [52526] (1 species)

   • Species Pseudomonas putida [TaxId:303] [52527] (2 PDB entries)

3. Pyruvate decarboxylase [52520] (3 species)

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52522] (2 PDB entries)

   2. Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] [52521] (1 PDB entry)

   3. Species Zymomonas mobilis [TaxId:542] [52523] (1 PDB entry)

4. Pyruvate oxidase [52524] (1 species)

   • Species Lactobacillus plantarum [TaxId:1590] [52525] (2 PDB entries)

More info for Family c.36.1.1: Pyruvate oxidase and decarboxylase THDP-binding domains

Timeline for Family c.36.1.1: Pyruvate oxidase and decarboxylase THDP-binding domains:

• Family c.36.1.1: Pyruvate oxidase and decarboxylase THDP-binding domains first appeared (with stable ids) in SCOP 1.55, called Family c.36.1.1: Pyruvate oxidase and decarboxylase
  
• Family c.36.1.1: Pyruvate oxidase and decarboxylase THDP-binding domains was called Family c.36.1.1: Pyruvate oxidase and decarboxylase in SCOP 1.61
  
• Family c.36.1.1: Pyruvate oxidase and decarboxylase THDP-binding domains does not appear in SCOP 1.65