SCOPe 2.01: Family c.34.1.1: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD

Lineage for Family c.34.1.1: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.34: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD [52506] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456

4. Superfamily c.34.1: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD [52507] (2 families)

5. Family c.34.1.1: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD [52508] (4 proteins)
   Pfam PF02441; formerly DFP, DNA/pantothenate metabolism flavoprotein family

Proteins:

1. 4'-phosphopantothenoylcysteine decarboxylase (PPC decarboxylase, halotolerance protein Hal3a) [52509] (2 species)
   involved in signal transduction; binds FMN

   1. Species Human (Homo sapiens) [TaxId:9606] [102300] (1 PDB entry)
      hypothetical protein mds018

   2. Species Mouse-ear cress (Arabidopsis thaliana) [TaxId:3702] [52510] (3 PDB entries)

2. Epidermin modifying enzyme (peptidyl-cysteine decarboxylase) EpiD [63996] (1 species)
   binds FMN

   • Species Staphylococcus epidermidis [TaxId:1282] [63997] (2 PDB entries)

3. MrsD [102301] (1 species)
   binds FAD

   • Species Bacillus sp. hil-y85/54728 [TaxId:69002] [102302] (1 PDB entry)

4. Probable aromatic acid decarboxylase Pad1 [117500] (1 species)

   • Species Escherichia coli O157:H7 [TaxId:83334] [117501] (1 PDB entry)
     Uniprot Q9X728

More info for Family c.34.1.1: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD

Timeline for Family c.34.1.1: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD:

• Family c.34.1.1: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD first appeared (with stable ids) in SCOP 1.55, called Family c.34.1.1: Halotolerance protein Hal3
  
• Family c.34.1.1: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD appears in SCOP 1.75
  
• Family c.34.1.1: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD appears in SCOPe 2.02
  
• Family c.34.1.1: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD appears in the current release, SCOPe 2.08