SCOP 1.67: Protein: Transhydrogenase domain III (dIII)

Root: SCOP 1.67
Class c: Alpha and beta proteins (a/b) [51349] (130 folds)
Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (5 families)
binds cofactor molecules in the opposite direction than classical Rossmann fold
Family c.31.1.4: Transhydrogenase domain III (dIII) [52484] (1 protein)
binds NADP, shares with the pyruvate oxidase FAD-binding domain a common ADP-binding mode
Protein Transhydrogenase domain III (dIII) [52485] (3 species)

Cow (Bos taurus) [TaxId:9913] [52487] (1 PDB entry)
- Domain for 1d4o:
  - Domain d1d4oa_: 1d4o A: [31748]
Human (Homo sapiens) [TaxId:9606] [52486] (2 PDB entries)
1. Domains for 1djl:
  1. Domain d1djla_: 1djl A: [31746]
  2. Domain d1djlb_: 1djl B: [31747]
    complexed with gol, nap, so4
2. Domains for 1pt9:
  1. Domain d1pt9a_: 1pt9 A: [95097]
  2. Domain d1pt9b_: 1pt9 B: [95098]
    complexed with gol, so4, tap
Rhodospirillum rubrum [TaxId:1085] [52488] (6 PDB entries)
1. Domain for 1e3t:
  - Domain d1e3ta_: 1e3t A: [31749]
    complexed with nap
2. Domain for 1hzz:
  - Domain d1hzzc_: 1hzz C: [61474]
    Other proteins in same PDB: d1hzza1, d1hzza2, d1hzzb1, d1hzzb2
    complexed with dI component
    complexed with nad, nap
3. Domain for 1nm5:
  - Domain d1nm5c_: 1nm5 C: [91972]
    Other proteins in same PDB: d1nm5a1, d1nm5a2, d1nm5b1, d1nm5b2
    complexed with dI component
    complexed with gol, nad, nap; mutant
4. Domains for 1pno:
  1. Domain d1pnoa_: 1pno A: [94953]
  2. Domain d1pnob_: 1pno B: [94954]
    complexed with nap
5. Domains for 1pnq:
  1. Domain d1pnqa_: 1pnq A: [94955]
  2. Domain d1pnqb_: 1pnq B: [94956]
    complexed with ndp
6. Domain for 1ptj:
  - Domain d1ptjc_: 1ptj C: [95103]
    Other proteins in same PDB: d1ptja1, d1ptja2, d1ptjb1, d1ptjb2
    complexed with dI component
    complexed with gol, nap, snd

Timeline for Protein Transhydrogenase domain III (dIII) from c.31.1.4: Transhydrogenase domain III (dIII):

Protein Transhydrogenase domain III (dIII) from c.31.1.4: Transhydrogenase domain III (dIII) first appeared (with stable ids) in SCOP 1.55
Protein Transhydrogenase domain III (dIII) from c.31.1.4: Transhydrogenase domain III (dIII) appears in SCOP 1.65
Protein Transhydrogenase domain III (dIII) from c.31.1.4: Transhydrogenase domain III (dIII) appears in SCOP 1.69
Protein Transhydrogenase domain III (dIII) from c.31.1.4: Transhydrogenase domain III (dIII) appears in the current release, SCOPe 2.08