SCOP 1.67: Protein: Pyruvate decarboxylase

Lineage for Protein: Pyruvate decarboxylase

Root: SCOP 1.67
Class c: Alpha and beta proteins (a/b) [51349] (130 folds)
Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (5 families)
binds cofactor molecules in the opposite direction than classical Rossmann fold
Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain [52475] (7 proteins)
N-terminal domain is Pyr module, and C-terminal domain is PP module of thiamin diphosphate-binding fold
Protein Pyruvate decarboxylase [52478] (3 species)
rudiment domain with a variant fold, lacks FAD-binding

Species:

Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52480] (2 PDB entries)
1. Domains for 1pvd:
  1. Domain d1pvda1: 1pvd A:182-360 [31737]
    Other proteins in same PDB: d1pvda2, d1pvda3, d1pvdb2, d1pvdb3
  2. Domain d1pvdb1: 1pvd B:182-360 [31738]
    Other proteins in same PDB: d1pvda2, d1pvda3, d1pvdb2, d1pvdb3
    complexed with mg, tpp
2. Domains for 1qpb:
  1. Domain d1qpba1: 1qpb A:182-360 [31739]
    Other proteins in same PDB: d1qpba2, d1qpba3, d1qpbb2, d1qpbb3
  2. Domain d1qpbb1: 1qpb B:182-360 [31740]
    Other proteins in same PDB: d1qpba2, d1qpba3, d1qpbb2, d1qpbb3
Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] [52479] (1 PDB entry)
- Domains for 1pyd:
  1. Domain d1pyda1: 1pyd A:182-360 [31735]
    Other proteins in same PDB: d1pyda2, d1pyda3, d1pydb2, d1pydb3
  2. Domain d1pydb1: 1pyd B:182-360 [31736]
    Other proteins in same PDB: d1pyda2, d1pyda3, d1pydb2, d1pydb3
    complexed with mg, tdp
Zymomonas mobilis [TaxId:542] [52481] (1 PDB entry)
- Domains for 1zpd:
  1. Domain d1zpda1: 1zpd A:188-362 [31741]
    Other proteins in same PDB: d1zpda2, d1zpda3, d1zpdb2, d1zpdb3, d1zpde2, d1zpde3, d1zpdf2, d1zpdf3
  2. Domain d1zpdb1: 1zpd B:188-362 [31742]
    Other proteins in same PDB: d1zpda2, d1zpda3, d1zpdb2, d1zpdb3, d1zpde2, d1zpde3, d1zpdf2, d1zpdf3
  3. Domain d1zpde1: 1zpd E:188-362 [31743]
    Other proteins in same PDB: d1zpda2, d1zpda3, d1zpdb2, d1zpdb3, d1zpde2, d1zpde3, d1zpdf2, d1zpdf3
  4. Domain d1zpdf1: 1zpd F:188-362 [31744]
    Other proteins in same PDB: d1zpda2, d1zpda3, d1zpdb2, d1zpdb3, d1zpde2, d1zpde3, d1zpdf2, d1zpdf3
    complexed with cit, dpx, mg

More info for Protein Pyruvate decarboxylase from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain

Timeline for Protein Pyruvate decarboxylase from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain:

Protein Pyruvate decarboxylase from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain first appeared (with stable ids) in SCOP 1.55
Protein Pyruvate decarboxylase from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain appears in SCOP 1.65
Protein Pyruvate decarboxylase from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain appears in SCOP 1.69
Protein Pyruvate decarboxylase from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain appears in the current release, SCOPe 2.08