Lineage for Protein: Pyruvate oxidase

  1. Root: SCOPe 2.02
  2. 1143363Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1161899Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 1161900Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 1161929Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain [52475] (8 proteins)
    N-terminal domain is Pyr module, and C-terminal domain is PP module of thiamin diphosphate-binding fold
  6. 1162050Protein Pyruvate oxidase [52476] (2 species)
    binds FAD

Species:

  1. 1162051Aerococcus viridans [TaxId:1377] [142122] (4 PDB entries)
    1. Domain for 1v5e:
    2. Domain for 1v5f:
    3. Domain for 1v5g:
    4. Domain for 2dji:
  2. 1162056Lactobacillus plantarum [TaxId:1590] [52477] (7 PDB entries)
    1. Domains for 1pow:
      1. 1162069Domain d1powa1: 1pow A:183-365 [31733]
        Other proteins in same PDB: d1powa2, d1powa3, d1powb2, d1powb3
        complexed with fad, mg, tpp; mutant
      2. 1162070Domain d1powb1: 1pow B:183-365 [31734]
        Other proteins in same PDB: d1powa2, d1powa3, d1powb2, d1powb3
        complexed with fad, mg, tpp; mutant
    2. Domains for 1pox:
      1. 1162063Domain d1poxa1: 1pox A:183-365 [31731]
        Other proteins in same PDB: d1poxa2, d1poxa3, d1poxb2, d1poxb3
        complexed with fad, gol, mg, na, tpp; mutant
      2. 1162064Domain d1poxb1: 1pox B:183-365 [31732]
        Other proteins in same PDB: d1poxa2, d1poxa3, d1poxb2, d1poxb3
        complexed with fad, gol, mg, na, tpp; mutant
    3. Domains for 2ez4:
      1. 1162061Domain d2ez4a1: 2ez4 A:183-365 [132610]
        Other proteins in same PDB: d2ez4a2, d2ez4a3, d2ez4b2, d2ez4b3
        automatically matched to d1powa1
        complexed with fad, mg, na, po4, tpp
      2. 1162062Domain d2ez4b1: 2ez4 B:183-365 [132613]
        Other proteins in same PDB: d2ez4a2, d2ez4a3, d2ez4b2, d2ez4b3
        automatically matched to d1powa1
        complexed with fad, mg, na, po4, tpp
    4. Domains for 2ez8:
      1. 1162059Domain d2ez8a1: 2ez8 A:183-365 [132621]
        Other proteins in same PDB: d2ez8a2, d2ez8a3, d2ez8b2, d2ez8b3
        automatically matched to d1powa1
        complexed with fad, mg, na, pyr, tdl
      2. 1162060Domain d2ez8b1: 2ez8 B:183-365 [132624]
        Other proteins in same PDB: d2ez8a2, d2ez8a3, d2ez8b2, d2ez8b3
        automatically matched to d1powa1
        complexed with fad, mg, na, pyr, tdl
    5. Domains for 2ez9:
      1. 1162057Domain d2ez9a1: 2ez9 A:183-365 [132627]
        Other proteins in same PDB: d2ez9a2, d2ez9a3, d2ez9b2, d2ez9b3
        automatically matched to d1powa1
        complexed with fad, mg, na, tdk
      2. 1162058Domain d2ez9b1: 2ez9 B:183-365 [132630]
        Other proteins in same PDB: d2ez9a2, d2ez9a3, d2ez9b2, d2ez9b3
        automatically matched to d1powa1
        complexed with fad, mg, na, tdk
    6. Domains for 2ezt:
      1. 1162067Domain d2ezta1: 2ezt A:183-365 [132633]
        Other proteins in same PDB: d2ezta2, d2ezta3, d2eztb2, d2eztb3
        automatically matched to d1powa1
        complexed with fad, mg, na, po4, pyr, tdm
      2. 1162068Domain d2eztb1: 2ezt B:183-365 [132636]
        Other proteins in same PDB: d2ezta2, d2ezta3, d2eztb2, d2eztb3
        automatically matched to d1powa1
        complexed with fad, mg, na, po4, pyr, tdm
    7. Domains for 2ezu:
      1. 1162065Domain d2ezua1: 2ezu A:183-365 [132639]
        Other proteins in same PDB: d2ezua2, d2ezua3, d2ezub2, d2ezub3
        automatically matched to d1powa1
        complexed with fad, htl, mg, na, pyr
      2. 1162066Domain d2ezub1: 2ezu B:183-365 [132642]
        Other proteins in same PDB: d2ezua2, d2ezua3, d2ezub2, d2ezub3
        automatically matched to d1powa1
        complexed with fad, htl, mg, na, pyr

More info for Protein Pyruvate oxidase from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain

Timeline for Protein Pyruvate oxidase from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain: