Lineage for Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain

  1. Root: SCOP 1.75
  2. 814173Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 828384Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 828385Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (6 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 828414Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain [52475] (8 proteins)
    N-terminal domain is Pyr module, and C-terminal domain is PP module of thiamin diphosphate-binding fold

Proteins:

  1. 828415Acetohydroxyacid synthase catalytic subunit [69463] (2 species)
    1. 828416Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [69464] (6 PDB entries)
      Uniprot P07342 84-687
    2. 828431Species Thale cress (Arabidopsis thaliana), chloroplast [TaxId:3702] [142123] (6 PDB entries)
      Uniprot P17597 281-459
  2. 828438Benzoylformate decarboxylase [52482] (1 species)
  3. 828467Carboxyethylarginine synthase [102290] (1 species)
  4. 828491Catabolic acetolactate synthase [102288] (1 species)
  5. 828501Indole-3-pyruvate decarboxylase [89637] (1 species)
  6. 828507Oxalyl-CoA decarboxylase [142124] (1 species)
  7. 828521Pyruvate decarboxylase [52478] (3 species)
    rudiment domain with a variant fold, lacks FAD-binding
    1. 828522Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52480] (2 PDB entries)
    2. 828527Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] [52479] (1 PDB entry)
    3. 828530Species Zymomonas mobilis [TaxId:542] [52481] (1 PDB entry)
  8. 828535Pyruvate oxidase [52476] (2 species)
    binds FAD
    1. 828536Species Aerococcus viridans [TaxId:1377] [142122] (4 PDB entries)
    2. 828541Species Lactobacillus plantarum [TaxId:1590] [52477] (7 PDB entries)

More info for Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain

Timeline for Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain: