Lineage for Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain

  1. Root: SCOP 1.67
  2. 383641Class c: Alpha and beta proteins (a/b) [51349] (130 folds)
  3. 392797Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 392798Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (5 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 392816Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain [52475] (7 proteins)
    N-terminal domain is Pyr module, and C-terminal domain is PP module of thiamin diphosphate-binding fold

Proteins:

  1. 392817Acetohydroxyacid synthase catalytic subunit [69463] (1 species)
  2. 392823Benzoylformate decarboxylase [52482] (1 species)
  3. 392842Carboxyethylarginine synthase [102290] (1 species)
  4. 392858Catabolic acetolactate synthase [102288] (1 species)
  5. 392868Indole-3-pyruvate decarboxylase [89637] (1 species)
  6. 392874Pyruvate decarboxylase [52478] (3 species)
    rudiment domain with a variant fold, lacks FAD-binding
    1. 392875Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52480] (2 PDB entries)
    2. 392880Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] [52479] (1 PDB entry)
    3. 392883Species Zymomonas mobilis [TaxId:542] [52481] (1 PDB entry)
  7. 392888Pyruvate oxidase [52476] (1 species)
    binds FAD

More info for Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain

Timeline for Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain: