SCOPe 2.06: Family c.30.1.1: BC N-terminal domain-like

Lineage for Family c.30.1.1: BC N-terminal domain-like

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.30: PreATP-grasp domain [52439] (1 superfamily)
   3 layers: a/b/a; parallel or mixed beta-sheet of 4 to 6 strands
   possible rudiment form of Rossmann-fold domain

4. Superfamily c.30.1: PreATP-grasp domain [52440] (10 families)
   precedes the ATP-grasp domain common to all superfamily members, can contain a substrate-binding function

5. Family c.30.1.1: BC N-terminal domain-like [52441] (6 proteins)

Proteins:

1. Acetyl-CoA carboxylase, BC-N subdomain [117496] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [117497] (2 PDB entries)
     Uniprot Q00955 13-566

2. Biotin carboxylase (BC), N-terminal domain [52442] (2 species)
   subunit of acetyl-CoA and pyruvate carboxylases

   1. Species Aquifex aeolicus [TaxId:63363] [102283] (1 PDB entry)

   2. Species Escherichia coli [TaxId:562] [52443] (24 PDB entries)

3. Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains [52450] (1 species)
   duplication: CPS large subunit contains two full BC-like lobes: carboxyphosphate and carbamoyl phosphate domains

   • Species Escherichia coli [TaxId:562] [52451] (10 PDB entries)
     Uniprot P00968

4. Glycinamide ribonucleotide synthetase (GAR-syn), N-domain [52444] (2 species)

   1. Species Escherichia coli [TaxId:562] [52445] (1 PDB entry)

   2. Species Thermotoga maritima [TaxId:2336] [110500] (1 PDB entry)
      Uniprot Q9X0X7

5. Glycinamide ribonucleotide transformylase PurT, N-domain [52448] (1 species)

   • Species Escherichia coli [TaxId:562] [52449] (7 PDB entries)

6. N5-carboxyaminoimidazole ribonucleotide synthetase PurK (AIRC), N-domain [52446] (1 species)

   • Species Escherichia coli [TaxId:562] [52447] (4 PDB entries)

More info for Family c.30.1.1: BC N-terminal domain-like

Timeline for Family c.30.1.1: BC N-terminal domain-like:

• Family c.30.1.1: BC N-terminal domain-like first appeared (with stable ids) in SCOP 1.55, called Family c.30.1.1: Biotin carboxylase/Carbamoyl phosphate synthetase
  
• Family c.30.1.1: BC N-terminal domain-like appears in SCOPe 2.05
  
• Family c.30.1.1: BC N-terminal domain-like appears in SCOPe 2.07
  
• Family c.30.1.1: BC N-terminal domain-like appears in the current release, SCOPe 2.08