SCOP 1.73: Protein: Tryptophanyl-tRNA synthetase (TrpRS)

Lineage for Protein: Tryptophanyl-tRNA synthetase (TrpRS)

Root: SCOP 1.73
Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
Fold c.26: Adenine nucleotide alpha hydrolase-like [52373] (3 superfamilies)
core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145
Superfamily c.26.1: Nucleotidylyl transferase [52374] (5 families)
Family c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain [52375] (12 proteins)
contains a conserved all-alpha subdomain at the C-terminal extension
Protein Tryptophanyl-tRNA synthetase (TrpRS) [52378] (2 species)
overall structure is similar to TyrRS

Species:

Bacillus stearothermophilus [TaxId:1422] [52379] (9 PDB entries)
1. Domains for 1d2r:
  1. Domain d1d2ra_: 1d2r A: [31572]
  2. Domain d1d2rb_: 1d2r B: [31573]
  3. Domain d1d2rc_: 1d2r C: [31574]
  4. Domain d1d2rd_: 1d2r D: [31575]
  5. Domain d1d2re_: 1d2r E: [31576]
  6. Domain d1d2rf_: 1d2r F: [31577]
2. Domain for 1i6k:
  - Domain d1i6ka_: 1i6k A: [66040]
    complexed with gol, nh4, so4, tym
3. Domain for 1i6l:
  - Domain d1i6la_: 1i6l A: [66041]
    complexed with gol, nh4, so4, tym
4. Domain for 1i6m:
  - Domain d1i6ma_: 1i6m A: [66042]
    complexed with gol, nh4, so4, tym
5. Domain for 1m83:
  - Domain d1m83a_: 1m83 A: [78767]
    complexed with atp, gol, mg
6. Domain for 1mau:
  - Domain d1maua_: 1mau A: [78892]
    complexed with atp, cit, gol, ltn, mg, na
7. Domains for 1maw:
  1. Domain d1mawa_: 1maw A: [78894]
  2. Domain d1mawb_: 1maw B: [78895]
  3. Domain d1mawc_: 1maw C: [78896]
  4. Domain d1mawd_: 1maw D: [78897]
  5. Domain d1mawe_: 1maw E: [78898]
  6. Domain d1mawf_: 1maw F: [78899]
    complexed with atp
8. Domains for 1mb2:
  1. Domain d1mb2a_: 1mb2 A: [78901]
  2. Domain d1mb2b_: 1mb2 B: [78902]
  3. Domain d1mb2c_: 1mb2 C: [78903]
  4. Domain d1mb2d_: 1mb2 D: [78904]
  5. Domain d1mb2e_: 1mb2 E: [78905]
  6. Domain d1mb2f_: 1mb2 F: [78906]
    complexed with ltr
9. Domain for 2ov4:
  - Domain d2ov4a1: 2ov4 A:1-328 [139379]
    automatically matched to d1m83a_
    complexed with anl, aqp, cs, gol
Human (Homo sapiens) [TaxId:9606] [102256] (7 PDB entries)
1. Domain for 1o5t:
  - Domain d1o5ta_: 1o5t A: [103891]
2. Domains for 1r6t:
  1. Domain d1r6ta2: 1r6t A:82-467 [97161]
    Other proteins in same PDB: d1r6ta1
    complexed with gol, tym; mutant
  2. Domain d1r6tb_: 1r6t B: [97162]
    Other proteins in same PDB: d1r6ta1
    complexed with gol, tym; mutant
3. Domains for 1r6u:
  1. Domain d1r6ua_: 1r6u A: [97163]
  2. Domain d1r6ub_: 1r6u B: [97164]
    complexed with gol, tym; mutant
4. Domains for 1ulh:
  1. Domain d1ulha_: 1ulh A: [99557]
  2. Domain d1ulhb_: 1ulh B: [99558]
5. Domain for 2ake:
  - Domain d2akea1: 2ake A:97-469 [126915]
    automatically matched to d1ulhb_
    complexed with so4, trp
6. Domains for 2azx:
  1. Domain d2azxa1: 2azx A:82-468 [127616]
    automatically matched to d1r6ua_
    complexed with gol, mg, so4, trp; mutant
  2. Domain d2azxb1: 2azx B:82-468 [127617]
    automatically matched to d1r6ua_
    complexed with gol, mg, so4, trp; mutant
7. Domain for 2dr2:
  - Domain d2dr2a1: 2dr2 A:97-469 [131653]
    automatically matched to d1ulhb_
    complexed with so4, trp

More info for Protein Tryptophanyl-tRNA synthetase (TrpRS) from c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain

Timeline for Protein Tryptophanyl-tRNA synthetase (TrpRS) from c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain:

Protein Tryptophanyl-tRNA synthetase (TrpRS) from c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain first appeared (with stable ids) in SCOP 1.55
Protein Tryptophanyl-tRNA synthetase (TrpRS) from c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain appears in SCOP 1.71
Protein Tryptophanyl-tRNA synthetase (TrpRS) from c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain appears in SCOP 1.75
Protein Tryptophanyl-tRNA synthetase (TrpRS) from c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain appears in the current release, SCOPe 2.08