Lineage for Protein: Tryptophanyl-tRNA synthetase (TrpRS)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2105373Fold c.26: Adenine nucleotide alpha hydrolase-like [52373] (3 superfamilies)
    core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145
  4. 2105374Superfamily c.26.1: Nucleotidylyl transferase [52374] (6 families) (S)
  5. 2105375Family c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain [52375] (13 protein domains)
    contains a conserved all-alpha subdomain at the C-terminal extension
  6. 2105469Protein Tryptophanyl-tRNA synthetase (TrpRS) [52378] (5 species)
    overall structure is similar to TyrRS

Species:

  1. 2105470Bacillus stearothermophilus [TaxId:1422] [52379] (12 PDB entries)
    1. Domains for 1d2r:
      1. 2105508Domain d1d2ra_: 1d2r A: [31572]
      2. 2105509Domain d1d2rb_: 1d2r B: [31573]
      3. 2105510Domain d1d2rc_: 1d2r C: [31574]
      4. 2105511Domain d1d2rd_: 1d2r D: [31575]
      5. 2105512Domain d1d2re_: 1d2r E: [31576]
      6. 2105513Domain d1d2rf_: 1d2r F: [31577]
    2. Domain for 1i6k:
      • 2105473Domain d1i6ka_: 1i6k A: [66040]
        protein/RNA complex; complexed with gol, nh4, so4, tym
    3. Domain for 1i6l:
      • 2105471Domain d1i6la_: 1i6l A: [66041]
        protein/RNA complex; complexed with gol, nh4, so4, tym
    4. Domain for 1i6m:
      • 2105472Domain d1i6ma_: 1i6m A: [66042]
        protein/RNA complex; complexed with gol, nh4, so4, tym
    5. Domain for 1m83:
      • 2105475Domain d1m83a_: 1m83 A: [78767]
        protein/RNA complex; complexed with atp, gol, mg
    6. Domain for 1mau:
      • 2105474Domain d1maua_: 1mau A: [78892]
        protein/RNA complex; complexed with atp, cit, gol, ltn, mg, na
    7. Domains for 1maw:
      1. 2105514Domain d1mawa_: 1maw A: [78894]
        protein/RNA complex; complexed with atp
      2. 2105515Domain d1mawb_: 1maw B: [78895]
        protein/RNA complex; complexed with atp
      3. 2105516Domain d1mawc_: 1maw C: [78896]
        protein/RNA complex; complexed with atp
      4. 2105517Domain d1mawd_: 1maw D: [78897]
        protein/RNA complex; complexed with atp
      5. 2105518Domain d1mawe_: 1maw E: [78898]
        protein/RNA complex; complexed with atp
      6. 2105519Domain d1mawf_: 1maw F: [78899]
        protein/RNA complex; complexed with atp
    8. Domains for 1mb2:
      1. 2105502Domain d1mb2a_: 1mb2 A: [78901]
        protein/RNA complex; complexed with trp
      2. 2105503Domain d1mb2b_: 1mb2 B: [78902]
        protein/RNA complex; complexed with trp
      3. 2105504Domain d1mb2c_: 1mb2 C: [78903]
        protein/RNA complex; complexed with trp
      4. 2105505Domain d1mb2d_: 1mb2 D: [78904]
        protein/RNA complex; complexed with trp
      5. 2105506Domain d1mb2e_: 1mb2 E: [78905]
        protein/RNA complex; complexed with trp
      6. 2105507Domain d1mb2f_: 1mb2 F: [78906]
        protein/RNA complex; complexed with trp
    9. Domain for 2ov4:
      • 2105477Domain d2ov4a_: 2ov4 A: [139379]
        automated match to d1m83a_
        protein/RNA complex; complexed with anl, aqp, cs, gol
    10. Domains for 3fhj:
      1. 2105496Domain d3fhja_: 3fhj A: [175784]
        automated match to d1m83a_
        complexed with amp, po4, trp
      2. 2105497Domain d3fhjb_: 3fhj B: [175785]
        automated match to d1m83a_
        complexed with amp, po4, trp
      3. 2105498Domain d3fhjc_: 3fhj C: [175786]
        automated match to d1m83a_
        complexed with amp, po4, trp
      4. 2105499Domain d3fhjd_: 3fhj D: [175787]
        automated match to d1m83a_
        complexed with amp, po4, trp
      5. 2105500Domain d3fhje_: 3fhj E: [175788]
        automated match to d1m83a_
        complexed with amp, po4, trp
      6. 2105501Domain d3fhjf_: 3fhj F: [175789]
        automated match to d1m83a_
        complexed with amp, po4, trp
    11. Domains for 3fi0:
      1. 2105478Domain d3fi0a_: 3fi0 A: [175798]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      2. 2105479Domain d3fi0b_: 3fi0 B: [175799]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      3. 2105480Domain d3fi0c_: 3fi0 C: [175800]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      4. 2105481Domain d3fi0d_: 3fi0 D: [175801]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      5. 2105482Domain d3fi0e_: 3fi0 E: [175802]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      6. 2105483Domain d3fi0f_: 3fi0 F: [175803]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      7. 2105484Domain d3fi0g_: 3fi0 G: [175804]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      8. 2105485Domain d3fi0h_: 3fi0 H: [175805]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      9. 2105486Domain d3fi0i_: 3fi0 I: [175806]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      10. 2105487Domain d3fi0j_: 3fi0 J: [175807]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      11. 2105488Domain d3fi0k_: 3fi0 K: [175808]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      12. 2105489Domain d3fi0l_: 3fi0 L: [175809]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      13. 2105490Domain d3fi0m_: 3fi0 M: [175810]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      14. 2105491Domain d3fi0n_: 3fi0 N: [175811]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      15. 2105492Domain d3fi0o_: 3fi0 O: [175812]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      16. 2105493Domain d3fi0p_: 3fi0 P: [175813]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      17. 2105494Domain d3fi0q_: 3fi0 Q: [175814]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      18. 2105495Domain d3fi0r_: 3fi0 R: [175815]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
    12. Domain for 5dk4:
  2. 2105520Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [255912] (4 PDB entries)
    1. Domain for 3kt0:
    2. Domains for 3kt3:
      1. 2105522Domain d3kt3a_: 3kt3 A: [247272]
        automated match to d1ulhb_
        protein/RNA complex; complexed with so4, tym
      2. 2105523Domain d3kt3b_: 3kt3 B: [247273]
        automated match to d1ulhb_
        protein/RNA complex; complexed with so4, tym
      3. 2105524Domain d3kt3c_: 3kt3 C: [247274]
        automated match to d1ulhb_
        protein/RNA complex; complexed with so4, tym
      4. 2105525Domain d3kt3d_: 3kt3 D: [247275]
        automated match to d1ulhb_
        protein/RNA complex; complexed with so4, tym
    3. Domains for 3kt6:
      1. 2105526Domain d3kt6a_: 3kt6 A: [247278]
        automated match to d1ulhb_
        protein/RNA complex; complexed with so4, trp
      2. 2105527Domain d3kt6b_: 3kt6 B: [247279]
        automated match to d1ulhb_
        protein/RNA complex; complexed with so4, trp
      3. 2105528Domain d3kt6c_: 3kt6 C: [247280]
        automated match to d1ulhb_
        protein/RNA complex; complexed with so4, trp
      4. 2105529Domain d3kt6d_: 3kt6 D: [247281]
        automated match to d1ulhb_
        protein/RNA complex; complexed with so4, trp
    4. Domains for 3kt8:
      1. 2105530Domain d3kt8a_: 3kt8 A: [247282]
        automated match to d1ulhb_
        protein/RNA complex; complexed with ltn, so4
      2. 2105531Domain d3kt8b_: 3kt8 B: [247283]
        automated match to d1ulhb_
        protein/RNA complex; complexed with ltn, so4
      3. 2105532Domain d3kt8c_: 3kt8 C: [247284]
        automated match to d1ulhb_
        protein/RNA complex; complexed with ltn, so4
      4. 2105533Domain d3kt8d_: 3kt8 D: [247285]
        automated match to d1ulhb_
        protein/RNA complex; complexed with ltn, so4
  3. 2105534Human (Homo sapiens) [TaxId:9606] [102256] (11 PDB entries)
    Uniprot P23381 94-471
    1. Domain for 1o5t:
    2. Domains for 1r6t:
      1. 2105535Domain d1r6ta2: 1r6t A:82-466 [97161]
        Other proteins in same PDB: d1r6ta1, d1r6ta3, d1r6tb2
        complexed with gol, tym
      2. 2105536Domain d1r6tb1: 1r6t B:97-466 [97162]
        Other proteins in same PDB: d1r6ta1, d1r6ta3, d1r6tb2
        complexed with gol, tym
    3. Domains for 1r6u:
      1. 2105537Domain d1r6ua_: 1r6u A: [97163]
        complexed with gol, tym
      2. 2105538Domain d1r6ub_: 1r6u B: [97164]
        complexed with gol, tym
    4. Domains for 1ulh:
      1. 2105545Domain d1ulha_: 1ulh A: [99557]
      2. 2105546Domain d1ulhb_: 1ulh B: [99558]
    5. Domain for 2ake:
    6. Domains for 2azx:
      1. 2105548Domain d2azxa1: 2azx A:82-468 [127616]
        automatically matched to d1r6ua_
        protein/RNA complex; complexed with gol, mg, so4, trp
      2. 2105549Domain d2azxb1: 2azx B:82-468 [127617]
        automatically matched to d1r6ua_
        protein/RNA complex; complexed with gol, mg, so4, trp
    7. Domain for 2dr2:
    8. Domains for 2quh:
      1. 2105543Domain d2quha2: 2quh A:97-471 [151369]
        Other proteins in same PDB: d2quha3, d2quhb3
        automated match to d1r6ua_
        protein/RNA complex; complexed with trp
      2. 2105544Domain d2quhb2: 2quh B:92-471 [151370]
        Other proteins in same PDB: d2quha3, d2quhb3
        automated match to d1r6ua_
        protein/RNA complex; complexed with trp
    9. Domains for 2qui:
      1. 2105541Domain d2quia_: 2qui A: [151371]
        Other proteins in same PDB: d2quib3
        automated match to d1r6ua_
        protein/RNA complex; complexed with atp, ltn, mg
      2. 2105542Domain d2quib2: 2qui B:97-471 [151372]
        Other proteins in same PDB: d2quib3
        automated match to d1r6ua_
        protein/RNA complex; complexed with atp, ltn, mg
    10. Domains for 2quj:
      1. 2105539Domain d2quja2: 2quj A:88-471 [151373]
        Other proteins in same PDB: d2quja3
        automated match to d1r6ua_
        protein/RNA complex; complexed with cl, gol, trp, tym
      2. 2105540Domain d2qujb_: 2quj B: [151374]
        Other proteins in same PDB: d2quja3
        automated match to d1r6ua_
        protein/RNA complex; complexed with cl, gol, trp, tym
    11. Domain for 2quk:
  4. 2105553Thermotoga maritima [TaxId:2336] [187734] (1 PDB entry)
  5. 2105555Thermus thermophilus HB8 [TaxId:300852] [188378] (1 PDB entry)

More info for Protein Tryptophanyl-tRNA synthetase (TrpRS) from c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain

Timeline for Protein Tryptophanyl-tRNA synthetase (TrpRS) from c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain: