Lineage for Protein: Tryptophanyl-tRNA synthetase (TrpRS)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2860044Fold c.26: Adenine nucleotide alpha hydrolase-like [52373] (3 superfamilies)
    core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145
  4. 2860045Superfamily c.26.1: Nucleotidylyl transferase [52374] (6 families) (S)
  5. 2860046Family c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain [52375] (13 proteins)
    contains a conserved all-alpha subdomain at the C-terminal extension
  6. 2860140Protein Tryptophanyl-tRNA synthetase (TrpRS) [52378] (5 species)
    overall structure is similar to TyrRS

Species:

  1. 2860141Bacillus stearothermophilus [TaxId:1422] [52379] (13 PDB entries)
    1. Domains for 1d2r:
      1. 2860179Domain d1d2ra_: 1d2r A: [31572]
      2. 2860180Domain d1d2rb_: 1d2r B: [31573]
      3. 2860181Domain d1d2rc_: 1d2r C: [31574]
      4. 2860182Domain d1d2rd_: 1d2r D: [31575]
      5. 2860183Domain d1d2re_: 1d2r E: [31576]
      6. 2860184Domain d1d2rf_: 1d2r F: [31577]
    2. Domain for 1i6k:
      • 2860143Domain d1i6ka_: 1i6k A: [66040]
        protein/RNA complex; complexed with gol, nh4, so4, tym
    3. Domain for 1i6l:
      • 2860144Domain d1i6la_: 1i6l A: [66041]
        protein/RNA complex; complexed with gol, nh4, so4, tym
    4. Domain for 1i6m:
      • 2860142Domain d1i6ma_: 1i6m A: [66042]
        protein/RNA complex; complexed with gol, nh4, so4, tym
    5. Domain for 1m83:
      • 2860145Domain d1m83a_: 1m83 A: [78767]
        protein/RNA complex; complexed with atp, gol, mg
    6. Domain for 1mau:
      • 2860148Domain d1maua_: 1mau A: [78892]
        protein/RNA complex; complexed with atp, cit, gol, ltn, mg, na
    7. Domains for 1maw:
      1. 2860185Domain d1mawa_: 1maw A: [78894]
        protein/RNA complex; complexed with atp
      2. 2860186Domain d1mawb_: 1maw B: [78895]
        protein/RNA complex; complexed with atp
      3. 2860187Domain d1mawc_: 1maw C: [78896]
        protein/RNA complex; complexed with atp
      4. 2860188Domain d1mawd_: 1maw D: [78897]
        protein/RNA complex; complexed with atp
      5. 2860189Domain d1mawe_: 1maw E: [78898]
        protein/RNA complex; complexed with atp
      6. 2860190Domain d1mawf_: 1maw F: [78899]
        protein/RNA complex; complexed with atp
    8. Domains for 1mb2:
      1. 2860155Domain d1mb2a_: 1mb2 A: [78901]
        protein/RNA complex; complexed with trp
      2. 2860156Domain d1mb2b_: 1mb2 B: [78902]
        protein/RNA complex; complexed with trp
      3. 2860157Domain d1mb2c_: 1mb2 C: [78903]
        protein/RNA complex; complexed with trp
      4. 2860158Domain d1mb2d_: 1mb2 D: [78904]
        protein/RNA complex; complexed with trp
      5. 2860159Domain d1mb2e_: 1mb2 E: [78905]
        protein/RNA complex; complexed with trp
      6. 2860160Domain d1mb2f_: 1mb2 F: [78906]
        protein/RNA complex; complexed with trp
    9. Domain for 2ov4:
      • 2860147Domain d2ov4a_: 2ov4 A: [139379]
        automated match to d1m83a_
        protein/RNA complex; complexed with anl, aqp, cs, gol
    10. Domains for 3fhj:
      1. 2860149Domain d3fhja_: 3fhj A: [175784]
        automated match to d1m83a_
        complexed with amp, po4, trp
      2. 2860150Domain d3fhjb_: 3fhj B: [175785]
        automated match to d1m83a_
        complexed with amp, po4, trp
      3. 2860151Domain d3fhjc_: 3fhj C: [175786]
        automated match to d1m83a_
        complexed with amp, po4, trp
      4. 2860152Domain d3fhjd_: 3fhj D: [175787]
        automated match to d1m83a_
        complexed with amp, po4, trp
      5. 2860153Domain d3fhje_: 3fhj E: [175788]
        automated match to d1m83a_
        complexed with amp, po4, trp
      6. 2860154Domain d3fhjf_: 3fhj F: [175789]
        automated match to d1m83a_
        complexed with amp, po4, trp
    11. Domains for 3fi0:
      1. 2860161Domain d3fi0a_: 3fi0 A: [175798]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      2. 2860162Domain d3fi0b_: 3fi0 B: [175799]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      3. 2860163Domain d3fi0c_: 3fi0 C: [175800]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      4. 2860164Domain d3fi0d_: 3fi0 D: [175801]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      5. 2860165Domain d3fi0e_: 3fi0 E: [175802]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      6. 2860166Domain d3fi0f_: 3fi0 F: [175803]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      7. 2860167Domain d3fi0g_: 3fi0 G: [175804]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      8. 2860168Domain d3fi0h_: 3fi0 H: [175805]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      9. 2860169Domain d3fi0i_: 3fi0 I: [175806]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      10. 2860170Domain d3fi0j_: 3fi0 J: [175807]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      11. 2860171Domain d3fi0k_: 3fi0 K: [175808]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      12. 2860172Domain d3fi0l_: 3fi0 L: [175809]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      13. 2860173Domain d3fi0m_: 3fi0 M: [175810]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      14. 2860174Domain d3fi0n_: 3fi0 N: [175811]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      15. 2860175Domain d3fi0o_: 3fi0 O: [175812]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      16. 2860176Domain d3fi0p_: 3fi0 P: [175813]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      17. 2860177Domain d3fi0q_: 3fi0 Q: [175814]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
      18. 2860178Domain d3fi0r_: 3fi0 R: [175815]
        automated match to d1d2ra_
        protein/RNA complex; complexed with amp, po4, trp
    12. Domain for 5dk4:
    13. Domains for 7cms:
      1. 3084528Domain d7cmsb_: 7cms B: [420845]
        automated match to d1m83a_
        protein/RNA complex; complexed with 9e0, po4
      2. 3084546Domain d7cmsa_: 7cms A: [420863]
        automated match to d1m83a_
        protein/RNA complex; complexed with 9e0, po4
  2. 2860191Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [255912] (4 PDB entries)
    1. Domain for 3kt0:
    2. Domains for 3kt3:
      1. 2860193Domain d3kt3a_: 3kt3 A: [247272]
        automated match to d1ulhb_
        protein/RNA complex; complexed with so4, tym
      2. 2860194Domain d3kt3b_: 3kt3 B: [247273]
        automated match to d1ulhb_
        protein/RNA complex; complexed with so4, tym
      3. 2860195Domain d3kt3c_: 3kt3 C: [247274]
        automated match to d1ulhb_
        protein/RNA complex; complexed with so4, tym
      4. 2860196Domain d3kt3d_: 3kt3 D: [247275]
        automated match to d1ulhb_
        protein/RNA complex; complexed with so4, tym
    3. Domains for 3kt6:
      1. 2860197Domain d3kt6a_: 3kt6 A: [247278]
        automated match to d1ulhb_
        protein/RNA complex; complexed with so4, trp
      2. 2860198Domain d3kt6b_: 3kt6 B: [247279]
        automated match to d1ulhb_
        protein/RNA complex; complexed with so4, trp
      3. 2860199Domain d3kt6c_: 3kt6 C: [247280]
        automated match to d1ulhb_
        protein/RNA complex; complexed with so4, trp
      4. 2860200Domain d3kt6d_: 3kt6 D: [247281]
        automated match to d1ulhb_
        protein/RNA complex; complexed with so4, trp
    4. Domains for 3kt8:
      1. 2860201Domain d3kt8a_: 3kt8 A: [247282]
        automated match to d1ulhb_
        protein/RNA complex; complexed with ltn, so4
      2. 2860202Domain d3kt8b_: 3kt8 B: [247283]
        automated match to d1ulhb_
        protein/RNA complex; complexed with ltn, so4
      3. 2860203Domain d3kt8c_: 3kt8 C: [247284]
        automated match to d1ulhb_
        protein/RNA complex; complexed with ltn, so4
      4. 2860204Domain d3kt8d_: 3kt8 D: [247285]
        automated match to d1ulhb_
        protein/RNA complex; complexed with ltn, so4
  3. 2860205Human (Homo sapiens) [TaxId:9606] [102256] (13 PDB entries)
    Uniprot P23381 94-471
    1. Domain for 1o5t:
    2. Domains for 1r6t:
      1. 2860206Domain d1r6ta2: 1r6t A:82-466 [97161]
        Other proteins in same PDB: d1r6ta1, d1r6ta3, d1r6tb2
        complexed with gol, tym
      2. 2860207Domain d1r6tb1: 1r6t B:97-466 [97162]
        Other proteins in same PDB: d1r6ta1, d1r6ta3, d1r6tb2
        complexed with gol, tym
    3. Domains for 1r6u:
      1. 2860208Domain d1r6ua_: 1r6u A: [97163]
        complexed with gol, tym
      2. 2860209Domain d1r6ub_: 1r6u B: [97164]
        complexed with gol, tym
    4. Domains for 1ulh:
      1. 2860216Domain d1ulha_: 1ulh A: [99557]
      2. 2860217Domain d1ulhb_: 1ulh B: [99558]
    5. Domain for 2ake:
    6. Domains for 2azx:
      1. 2860220Domain d2azxa1: 2azx A:82-468 [127616]
        automatically matched to d1r6ua_
        protein/RNA complex; complexed with gol, mg, so4, trp
      2. 2860221Domain d2azxb1: 2azx B:82-468 [127617]
        automatically matched to d1r6ua_
        protein/RNA complex; complexed with gol, mg, so4, trp
    7. Domain for 2dr2:
    8. Domains for 2quh:
      1. 2860214Domain d2quha2: 2quh A:97-471 [151369]
        Other proteins in same PDB: d2quha3, d2quhb3
        automated match to d1r6ua_
        protein/RNA complex; complexed with trp
      2. 2860215Domain d2quhb2: 2quh B:92-471 [151370]
        Other proteins in same PDB: d2quha3, d2quhb3
        automated match to d1r6ua_
        protein/RNA complex; complexed with trp
    9. Domains for 2qui:
      1. 2860212Domain d2quia_: 2qui A: [151371]
        Other proteins in same PDB: d2quib3
        automated match to d1r6ua_
        protein/RNA complex; complexed with atp, ltn, mg
      2. 2860213Domain d2quib2: 2qui B:97-471 [151372]
        Other proteins in same PDB: d2quib3
        automated match to d1r6ua_
        protein/RNA complex; complexed with atp, ltn, mg
    10. Domains for 2quj:
      1. 2860210Domain d2quja2: 2quj A:88-471 [151373]
        Other proteins in same PDB: d2quja3
        automated match to d1r6ua_
        protein/RNA complex; complexed with cl, gol, trp, tym
      2. 2860211Domain d2qujb_: 2quj B: [151374]
        Other proteins in same PDB: d2quja3
        automated match to d1r6ua_
        protein/RNA complex; complexed with cl, gol, trp, tym
    11. Domain for 2quk:
    12. Domains for 5uji:
      1. 2860224Domain d5ujia_: 5uji A: [347662]
        automated match to d2qujb_
        mutant
      2. 2860225Domain d5ujib_: 5uji B: [347641]
        automated match to d2qujb_
        mutant
    13. Domain for 5ujj:
  4. 2860227Thermotoga maritima [TaxId:2336] [187734] (1 PDB entry)
  5. 2860229Thermus thermophilus HB8 [TaxId:300852] [188378] (1 PDB entry)

More info for Protein Tryptophanyl-tRNA synthetase (TrpRS) from c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain

Timeline for Protein Tryptophanyl-tRNA synthetase (TrpRS) from c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain: