Lineage for Protein: Tyrosyl-tRNA synthetase (TyrRS)

  1. Root: SCOP 1.69
  2. 473232Class c: Alpha and beta proteins (a/b) [51349] (136 folds)
  3. 482378Fold c.26: Adenine nucleotide alpha hydrolase-like [52373] (3 superfamilies)
    core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145
  4. 482379Superfamily c.26.1: Nucleotidylyl transferase [52374] (5 families) (S)
  5. 482380Family c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain [52375] (12 proteins)
    contains a conserved all-alpha subdomain at the C-terminal extension
  6. 482489Protein Tyrosyl-tRNA synthetase (TyrRS) [52376] (5 species)

Species:

  1. 482490Archaeon Methanococcus jannaschii [TaxId:2190] [89611] (1 PDB entry)
  2. 482492Bacillus stearothermophilus, nca 1503 [TaxId:1422] [52377] (7 PDB entries)
    1. Domain for 1tya:
    2. Domain for 1tyb:
    3. Domain for 1tyc:
    4. Domain for 1tyd:
    5. Domain for 2ts1:
    6. Domain for 3ts1:
    7. Domains for 4ts1:
      1. 482494Domain d4ts1a_: 4ts1 A: [31565]
      2. 482495Domain d4ts1b_: 4ts1 B: [31566]
  3. 482501Human (Homo sapiens) [TaxId:9606] [82355] (2 PDB entries)
    1. Domain for 1n3l:
      • 482502Domain d1n3la_: 1n3l A: [79966]
        mini-TyrRS; anticodon recognition part is more divergent; secreted cytokine with IL-8-like activity
    2. Domain for 1q11:
  4. 482504Staphylococcus aureus [TaxId:1280] [69453] (4 PDB entries)
    1. Domain for 1jii:
    2. Domain for 1jij:
    3. Domain for 1jik:
    4. Domain for 1jil:
  5. 482509Thermus thermophilus [TaxId:274] [82354] (2 PDB entries)
    1. Domain for 1h3e:
    2. Domains for 1h3f:
      1. 482510Domain d1h3fa1: 1h3f A:5-347 [76631]
        Other proteins in same PDB: d1h3fa2, d1h3fb2
      2. 482511Domain d1h3fb1: 1h3f B:5-343 [76633]
        Other proteins in same PDB: d1h3fa2, d1h3fb2

More info for Protein Tyrosyl-tRNA synthetase (TyrRS) from c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain

Timeline for Protein Tyrosyl-tRNA synthetase (TyrRS) from c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain: