| Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
| Fold c.26: Adenine nucleotide alpha hydrolase-like [52373] (3 superfamilies) core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145 |
Superfamily c.26.1: Nucleotidylyl transferase [52374] (6 families) ![]() |
| Family c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain [52375] (13 proteins) contains a conserved all-alpha subdomain at the C-terminal extension |
| Protein Tyrosyl-tRNA synthetase (TyrRS) [52376] (6 species) |
| Bacillus stearothermophilus, nca 1503 [TaxId:1422] [52377] (7 PDB entries) |
| Domain d1tyae_: 1tya E: [31570] complexed with tyr; mutant |
| Domain d1tybe_: 1tyb E: [31569] complexed with tyr; mutant |
| Domain d1tyca_: 1tyc A: [31568] mutant |
| Domain d1tyde_: 1tyd E: [31567] complexed with tyr |
| Domain d2ts1a_: 2ts1 A: [31564] |
| Domain d3ts1a_: 3ts1 A: [31571] complexed with tya |
| Domain d4ts1a_: 4ts1 A: [31565] protein/RNA complex; complexed with tyr; mutant |
| Domain d4ts1b_: 4ts1 B: [31566] protein/RNA complex; complexed with tyr; mutant |
| Escherichia coli [TaxId:316407] [188087] (3 PDB entries) |
| Domain d1wq3a_: 1wq3 A: [161975] automated match to d1tyae_ protein/RNA complex; complexed with iyr; mutant |
| Domain d1wq4a_: 1wq4 A: [161976] automated match to d1tyae_ protein/RNA complex; complexed with tyr; mutant |
| Domain d2yxna_: 2yxn A: [170916] automated match to d1tyae_ complexed with azy |
| Human (Homo sapiens) [TaxId:9606] [82355] (6 PDB entries) |
| Domain d1n3la_: 1n3l A: [79966] mini-TyrRS; anticodon recognition part is more divergent; secreted cytokine with IL-8-like activity complexed with gol, so4 |
| Domain d1q11a_: 1q11 A: [95528] mini-TyrRS complexed with gol, k, po4, tye |
| Domain d4q93a_: 4q93 A: [261906] automated match to d1n3la_ complexed with cl, gol, po4, so4, stl |
| Domain d4qbta_: 4qbt A: [261907] automated match to d1n3la_ complexed with gol, k, po4, so4, tyr |
| Domain d5thha_: 5thh A: [334377] automated match to d1n3la_ complexed with tyr; mutant |
| Domain d5thla_: 5thl A: [335207] automated match to d1n3la_ mutant |
| Methanococcus jannaschii [TaxId:2190] [89611] (9 PDB entries) |
| Domain d1j1ua_: 1j1u A: [83980] protein/RNA complex; complexed with mg, tyr |
| Domain d1u7da_: 1u7d A: [119615] automated match to d1j1ua_ |
| Domain d1u7db_: 1u7d B: [119616] automated match to d1j1ua_ |
| Domain d1u7xa_: 1u7x A: [240779] automated match to d2ag6a_ complexed with k; mutant |
| Domain d1u7xb_: 1u7x B: [240780] automated match to d2ag6a_ complexed with k; mutant |
| Domain d1zh6a1: 1zh6 A:1-306 [162473] Other proteins in same PDB: d1zh6a2 automated match to d1j1ua_ protein/RNA complex; complexed with 4af, bme |
| Domain d2ag6a1: 2ag6 A:1-306 [162777] Other proteins in same PDB: d2ag6a2 automated match to d1j1ua_ protein/RNA complex; complexed with 4bf |
| Domain d2hgza1: 2hgz A:2-306 [165110] Other proteins in same PDB: d2hgza2 automated match to d1j1ua_ complexed with pbf |
| Domain d2q1ga1: 2q1g A:2-306 [304393] Other proteins in same PDB: d2q1ga2 automated match to d2ag6a_ complexed with bme, t11 |
| Domain d2q1ia1: 2q1i A:2-306 [304395] Other proteins in same PDB: d2q1ia2 automated match to d4nd7a_ complexed with bme, tfq |
| Domain d3n2ya_: 3n2y A: [181859] automated match to d1j1ua_ protein/RNA complex; complexed with tef |
| Domain d3n2yb_: 3n2y B: [181860] automated match to d1j1ua_ protein/RNA complex; complexed with tef |
| Staphylococcus aureus [TaxId:1280] [69453] (4 PDB entries) |
| Domain d1jiia_: 1jii A: [66742] complexed with 383 |
| Domain d1jija_: 1jij A: [66743] complexed with 629 |
| Domain d1jika_: 1jik A: [66744] complexed with 545 |
| Domain d1jila_: 1jil A: [66745] complexed with 485 |
| Thermus thermophilus [TaxId:274] [82354] (2 PDB entries) |
| Domain d1h3ea1: 1h3e A:6-351 [76629] Other proteins in same PDB: d1h3ea2 protein/RNA complex; complexed with atp, tye |
| Domain d1h3fa1: 1h3f A:5-347 [76631] Other proteins in same PDB: d1h3fa2, d1h3fb2 protein/RNA complex; complexed with so4, tye |
| Domain d1h3fb1: 1h3f B:5-343 [76633] Other proteins in same PDB: d1h3fa2, d1h3fb2 protein/RNA complex; complexed with so4, tye |
Timeline for Protein Tyrosyl-tRNA synthetase (TyrRS) from c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain: