Lineage for Protein: Tyrosyl-tRNA synthetase (TyrRS)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2105373Fold c.26: Adenine nucleotide alpha hydrolase-like [52373] (3 superfamilies)
    core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145
  4. 2105374Superfamily c.26.1: Nucleotidylyl transferase [52374] (6 families) (S)
  5. 2105375Family c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain [52375] (13 protein domains)
    contains a conserved all-alpha subdomain at the C-terminal extension
  6. 2105558Protein Tyrosyl-tRNA synthetase (TyrRS) [52376] (6 species)

Species:

  1. 2105559Bacillus stearothermophilus, nca 1503 [TaxId:1422] [52377] (7 PDB entries)
    1. Domain for 1tya:
    2. Domain for 1tyb:
    3. Domain for 1tyc:
    4. Domain for 1tyd:
    5. Domain for 2ts1:
    6. Domain for 3ts1:
    7. Domains for 4ts1:
      1. 2105560Domain d4ts1a_: 4ts1 A: [31565]
        protein/RNA complex; complexed with tyr; mutant
      2. 2105561Domain d4ts1b_: 4ts1 B: [31566]
        protein/RNA complex; complexed with tyr; mutant
  2. 2105568Escherichia coli [TaxId:316407] [188087] (3 PDB entries)
    1. Domain for 1wq3:
    2. Domain for 1wq4:
    3. Domain for 2yxn:
  3. 2105572Human (Homo sapiens) [TaxId:9606] [82355] (6 PDB entries)
    1. Domain for 1n3l:
      • 2105573Domain d1n3la_: 1n3l A: [79966]
        mini-TyrRS; anticodon recognition part is more divergent; secreted cytokine with IL-8-like activity
        complexed with gol, so4
    2. Domain for 1q11:
    3. Domain for 4q93:
    4. Domain for 4qbt:
    5. Domain for 5thh:
    6. Domain for 5thl:
  4. 2105577Methanococcus jannaschii [TaxId:2190] [89611] (9 PDB entries)
    1. Domain for 1j1u:
    2. Domains for 1u7d:
      1. 2105586Domain d1u7da_: 1u7d A: [119615]
        automated match to d1j1ua_
      2. 2105587Domain d1u7db_: 1u7d B: [119616]
        automated match to d1j1ua_
    3. Domains for 1u7x:
      1. 2105588Domain d1u7xa_: 1u7x A: [240779]
        automated match to d2ag6a_
        complexed with k; mutant
      2. 2105589Domain d1u7xb_: 1u7x B: [240780]
        automated match to d2ag6a_
        complexed with k; mutant
    4. Domain for 1zh6:
    5. Domain for 2ag6:
    6. Domain for 2hgz:
    7. Domain for 2q1g:
    8. Domain for 2q1i:
    9. Domains for 3n2y:
      1. 2105584Domain d3n2ya_: 3n2y A: [181859]
        automated match to d1j1ua_
        protein/RNA complex; complexed with tef
      2. 2105585Domain d3n2yb_: 3n2y B: [181860]
        automated match to d1j1ua_
        protein/RNA complex; complexed with tef
  5. 2105590Staphylococcus aureus [TaxId:1280] [69453] (4 PDB entries)
    1. Domain for 1jii:
    2. Domain for 1jij:
    3. Domain for 1jik:
    4. Domain for 1jil:
  6. 2105595Thermus thermophilus [TaxId:274] [82354] (2 PDB entries)
    1. Domain for 1h3e:
    2. Domains for 1h3f:
      1. 2105596Domain d1h3fa1: 1h3f A:5-347 [76631]
        Other proteins in same PDB: d1h3fa2, d1h3fb2
        protein/RNA complex; complexed with so4, tye
      2. 2105597Domain d1h3fb1: 1h3f B:5-343 [76633]
        Other proteins in same PDB: d1h3fa2, d1h3fb2
        protein/RNA complex; complexed with so4, tye

More info for Protein Tyrosyl-tRNA synthetase (TyrRS) from c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain

Timeline for Protein Tyrosyl-tRNA synthetase (TyrRS) from c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain: