Lineage for Family c.25.1.3: Dihydroorotate dehydrogenase B, PyrK subunit

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.25: Ferredoxin reductase-like, C-terminal NADP-linked domain [52342] (1 superfamily) 3 layers, a/b/a; parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.25.1: Ferredoxin reductase-like, C-terminal NADP-linked domain [52343] (6 families) binds NADP differently than classical Rossmann-fold N-terminal FAD-linked domain contains (6,10) barrel

5. Family c.25.1.3: Dihydroorotate dehydrogenase B, PyrK subunit [52362] (1 protein) contains 2Fe-2S cluster in the C-terminal extension