SCOPe 2.04: Family c.25.1.1: Reductases

Lineage for Family c.25.1.1: Reductases

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.25: Ferredoxin reductase-like, C-terminal NADP-linked domain [52342] (1 superfamily)
   3 layers, a/b/a; parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.25.1: Ferredoxin reductase-like, C-terminal NADP-linked domain [52343] (6 families)
   binds NADP differently than classical Rossmann-fold
   N-terminal FAD-linked domain contains (6,10) barrel

5. Family c.25.1.1: Reductases [52344] (5 proteins)

Proteins:

1. cytochrome b5 reductase [52357] (3 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [117484] (1 PDB entry)
      Uniprot P00387 30-300

   2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [69450] (3 PDB entries)
      Uniprot P20070 33-300

   3. Species Pig (Sus scrofa), liver [TaxId:9823] [52358] (7 PDB entries)

2. Ferredoxin reductase (flavodoxin reductase) [52345] (9 species)

   1. Species Anabaena sp., pcc 7119 [TaxId:1167] [52350] (19 PDB entries)

   2. Species Azotobacter vinelandii [TaxId:354] [52352] (1 PDB entry)

   3. Species Escherichia coli [TaxId:562] [52351] (1 PDB entry)

   4. Species Maize (Zea mays), leaf isoform [TaxId:4577] [52349] (2 PDB entries)

   5. Species Maize (Zea mays), root isoform [TaxId:4577] [63974] (1 PDB entry)

   6. Species Paprika (Capsicum annuum) [TaxId:4072] [52348] (1 PDB entry)

   7. Species Pea (Pisum sativum) [TaxId:3888] [52347] (4 PDB entries)

   8. Species Pseudomonas aeruginosa [TaxId:287] [225369] (2 PDB entries)

   9. Species Spinach (Spinacia oleracea) [TaxId:3562] [52346] (7 PDB entries)

3. NAD(P)H:flavin oxidoreductase [52353] (1 species)

   • Species Escherichia coli [TaxId:562] [52354] (1 PDB entry)

4. Nitrate reductase [52355] (1 species)

   • Species Maize (Zea mays) [TaxId:4577] [52356] (3 PDB entries)

5. automated matches [226995] (7 species)
   not a true protein

   1. Species Anabaena pcc7119 [TaxId:1168] [254931] (1 PDB entry)

   2. Species Anabaena sp. [TaxId:1167] [229046] (3 PDB entries)

   3. Species Anabaena sp. [TaxId:1168] [254932] (3 PDB entries)

   4. Species Escherichia coli [TaxId:562] [226085] (1 PDB entry)

   5. Species Nostoc sp. [TaxId:1168] [229177] (3 PDB entries)

   6. Species Pea (Pisum sativum) [TaxId:3888] [226086] (3 PDB entries)

   7. Species Salmonella typhimurium [TaxId:99287] [225605] (1 PDB entry)

More info for Family c.25.1.1: Reductases

Timeline for Family c.25.1.1: Reductases:

• Family c.25.1.1: Reductases first appeared (with stable ids) in SCOP 1.55
  
• Family c.25.1.1: Reductases appears in SCOPe 2.03
  
• Family c.25.1.1: Reductases appears in SCOPe 2.05
  
• Family c.25.1.1: Reductases appears in the current release, SCOPe 2.08