SCOP 1.75: Family c.25.1.1: Reductases

Lineage for Family c.25.1.1: Reductases

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.25: Ferredoxin reductase-like, C-terminal NADP-linked domain [52342] (1 superfamily)
   3 layers, a/b/a; parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.25.1: Ferredoxin reductase-like, C-terminal NADP-linked domain [52343] (5 families)
   binds NADP differently than classical Rossmann-fold
   N-terminal FAD-linked domain contains (6,10) barrel

5. Family c.25.1.1: Reductases [52344] (4 proteins)

Proteins:

1. cytochrome b5 reductase [52357] (3 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [117484] (1 PDB entry)
      Uniprot P00387 30-300

   2. Species Pig (Sus scrofa), liver [TaxId:9823] [52358] (1 PDB entry)

   3. Species Rat (Rattus norvegicus) [TaxId:10116] [69450] (3 PDB entries)
      Uniprot P20070 33-300

2. Ferredoxin reductase (flavodoxin reductase) [52345] (8 species)

   1. Species Azotobacter vinelandii [TaxId:354] [52352] (1 PDB entry)

   2. Species Cyanobacterium (Anabaena sp.), pcc 7119 [TaxId:1167] [52350] (24 PDB entries)

   3. Species Escherichia coli [TaxId:562] [52351] (1 PDB entry)

   4. Species Garden pea (Pisum sativum) [TaxId:3888] [52347] (4 PDB entries)

   5. Species Maize (Zea mays), leaf isoform [TaxId:4577] [52349] (2 PDB entries)

   6. Species Maize (Zea mays), root isoform [TaxId:4577] [63974] (1 PDB entry)

   7. Species Paprika (Capsicum annuum) [TaxId:4072] [52348] (1 PDB entry)

   8. Species Spinach (Spinacia oleracea) [TaxId:3562] [52346] (7 PDB entries)

3. NAD(P)H:flavin oxidoreductase [52353] (1 species)

   • Species Escherichia coli [TaxId:562] [52354] (1 PDB entry)

4. Nitrate reductase [52355] (1 species)

   • Species Corn (Zea mays) [TaxId:4577] [52356] (3 PDB entries)

More info for Family c.25.1.1: Reductases

Timeline for Family c.25.1.1: Reductases:

• Family c.25.1.1: Reductases first appeared (with stable ids) in SCOP 1.55
  
• Family c.25.1.1: Reductases appears in SCOP 1.73
  
• Family c.25.1.1: Reductases appears in SCOPe 2.01
  
• Family c.25.1.1: Reductases appears in the current release, SCOPe 2.08