Lineage for Family c.23.12.1: Formate/glycerate dehydrogenases, substrate-binding domain

  1. Root: SCOPe 2.06
  2. 2089713Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2114715Fold c.23: Flavodoxin-like [52171] (15 superfamilies)
    3 layers, a/b/a; parallel beta-sheet of 5 strand, order 21345
  4. 2116681Superfamily c.23.12: Formate/glycerate dehydrogenase catalytic domain-like [52283] (3 families) (S)
  5. 2116682Family c.23.12.1: Formate/glycerate dehydrogenases, substrate-binding domain [52284] (7 proteins)
    this domain is interrupted by the Rossmann-fold domain

Proteins:

  1. 2116683D-2-hydroxyisocaproate dehydrogenase [52289] (1 species)
  2. 2116686D-glycerate dehydrogenase [52291] (1 species)
  3. 2116690D-lactate dehydrogenase [52295] (1 species)
  4. 2116700Formate dehydrogenase [52285] (1 species)
    contains an additional beta-hairpin after the common fold
  5. 2116706Phosphoglycerate dehydrogenase [52293] (2 species)
    has additional C-terminal domain of the ferredoxin fold
    1. 2116707Species Escherichia coli [TaxId:562] [52294] (7 PDB entries)
    2. 2116727Species Mycobacterium tuberculosis [TaxId:1773] [142063] (2 PDB entries)
      Uniprot P0A544 2-97,282-315
      there is an intervening domain between this domain and regulatory (C-terminal) domain
  6. 2116732Putative formate dehydrogenase [52287] (1 species)
  7. 2116736Transcription corepressor CtbP [82347] (2 species)
    C-terminal binding protein 1; a dehydrogenase
    1. 2116737Species Human (Homo sapiens), Ctbp1 [TaxId:9606] [82348] (4 PDB entries)
    2. 2116742Species Norway rat (Rattus norvegicus), Ctbp3 [TaxId:10116] [89597] (2 PDB entries)

More info for Family c.23.12.1: Formate/glycerate dehydrogenases, substrate-binding domain

Timeline for Family c.23.12.1: Formate/glycerate dehydrogenases, substrate-binding domain: