SCOPe 2.08: Family c.23.4.1: Succinyl-CoA synthetase domains

Lineage for Family c.23.4.1: Succinyl-CoA synthetase domains

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.23: Flavodoxin-like [52171] (15 superfamilies)
   3 layers, a/b/a; parallel beta-sheet of 5 strand, order 21345

4. Superfamily c.23.4: Succinyl-CoA synthetase domains [52210] (2 families)

5. Family c.23.4.1: Succinyl-CoA synthetase domains [52211] (3 proteins)
   contain additional N-terminal strand "0", antiparallel to strand 2

Proteins:

1. Acetate-CoA ligase alpha chain, AcdA, domains 2 and 3 [142043] (1 species)
   duplication: tandem repeat of two similar domains, structurally and functionally related to the C-terminal domains of Succinyl-CoA synthetase subunits; the first domain (2) is related to the alpha-chain domain, whereas the second domain (3) is related to the beta-chain domain

   • Species Pyrococcus horikoshii [TaxId:53953] [142044] (1 PDB entry)
     Uniprot O58493 130-290! Uniprot O58493 291-453
     PH0766

2. Succinyl-CoA synthetase, alpha-chain, C-terminal domain [52212] (6 species)

   1. Species Aeropyrum pernix [TaxId:272557] [225352] (1 PDB entry)

   2. Species Escherichia coli [TaxId:562] [52213] (11 PDB entries)

   3. Species Human (Homo sapiens) [TaxId:9606] [350889] (2 PDB entries)

   4. Species Methanocaldococcus jannaschii [TaxId:243232] [225350] (1 PDB entry)

   5. Species Pig (Sus scrofa) [TaxId:9823] [52214] (13 PDB entries)

   6. Species Thermus thermophilus [TaxId:274] [89589] (1 PDB entry)

3. Succinyl-CoA synthetase, beta-chain, C-terminal domain [52215] (3 species)

   1. Species Escherichia coli [TaxId:562] [52216] (11 PDB entries)

   2. Species Human (Homo sapiens) [TaxId:9606] [389535] (1 PDB entry)

   3. Species Pig (Sus scrofa) [TaxId:9823] [52217] (13 PDB entries)

More info for Family c.23.4.1: Succinyl-CoA synthetase domains

Timeline for Family c.23.4.1: Succinyl-CoA synthetase domains:

• Family c.23.4.1: Succinyl-CoA synthetase domains first appeared (with stable ids) in SCOP 1.55
  
• Family c.23.4.1: Succinyl-CoA synthetase domains appears in SCOPe 2.07