Lineage for Superfamily c.8.2: LeuD/IlvD-like

  1. Root: SCOP 1.75
  2. 814173Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 823456Fold c.8: The "swivelling" beta/beta/alpha domain [52008] (10 superfamilies)
    3 layers: b/b/a; the central sheet is parallel, and the other one is antiparallel; there are some variations in topology
    this domain is thought to be mobile in most multi-domain proteins known to contain it
  4. 823489Superfamily c.8.2: LeuD/IlvD-like [52016] (3 families) (S)
    contains mixed beta-sheet barrel, closed n=7, S=10


  1. 823490c.8.2.1: LeuD-like [52017] (4 proteins)
    Pfam PF00694; permutation of the domain order in the proteins containing this family domain
  2. 823522c.8.2.2: IlvD/EDD C-terminal domain-like [141976] (1 protein)
    C-terminal part of Pfam PF00920
  3. 823527c.8.2.3: AF0055-like [141979] (1 protein)
    PF01989; DUF126; probable link between the LeuD-like and Phosphohistidine domain superfamilies (sequence similarity crosshits)

More info for Superfamily c.8.2: LeuD/IlvD-like

Timeline for Superfamily c.8.2: LeuD/IlvD-like: