Lineage for Protein: Trypanothione reductase

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2096453Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
    core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander
  4. 2096454Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (9 families) (S)
  5. 2096984Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (15 protein domains)
    duplication: both domains have similar folds and functions
    most members of the family contain common C-terminal alpha+beta domain
  6. 2097273Protein Trypanothione reductase [51947] (3 species)

Species:

  1. 2097274Crithidia fasciculata [TaxId:5656] [51948] (6 PDB entries)
    1. Domains for 1fea:
      1. 2097283Domain d1feaa1: 1fea A:1-169,A:287-357 [30497]
        Other proteins in same PDB: d1feaa3, d1feab3, d1feac3, d1fead3
        complexed with fad
      2. 2097284Domain d1feaa2: 1fea A:170-286 [30498]
        Other proteins in same PDB: d1feaa3, d1feab3, d1feac3, d1fead3
        complexed with fad
      3. 2097285Domain d1feab1: 1fea B:1-169,B:287-357 [30499]
        Other proteins in same PDB: d1feaa3, d1feab3, d1feac3, d1fead3
        complexed with fad
      4. 2097286Domain d1feab2: 1fea B:170-286 [30500]
        Other proteins in same PDB: d1feaa3, d1feab3, d1feac3, d1fead3
        complexed with fad
      5. 2097287Domain d1feac1: 1fea C:1-169,C:287-357 [30501]
        Other proteins in same PDB: d1feaa3, d1feab3, d1feac3, d1fead3
        complexed with fad
      6. 2097288Domain d1feac2: 1fea C:170-286 [30502]
        Other proteins in same PDB: d1feaa3, d1feab3, d1feac3, d1fead3
        complexed with fad
      7. 2097289Domain d1fead1: 1fea D:1-169,D:287-357 [30503]
        Other proteins in same PDB: d1feaa3, d1feab3, d1feac3, d1fead3
        complexed with fad
      8. 2097290Domain d1fead2: 1fea D:170-286 [30504]
        Other proteins in same PDB: d1feaa3, d1feab3, d1feac3, d1fead3
        complexed with fad
    2. Domains for 1feb:
      1. 2097279Domain d1feba1: 1feb A:1-169,A:287-357 [30493]
        Other proteins in same PDB: d1feba3, d1febb3
        complexed with fad
      2. 2097280Domain d1feba2: 1feb A:170-286 [30494]
        Other proteins in same PDB: d1feba3, d1febb3
        complexed with fad
      3. 2097281Domain d1febb1: 1feb B:1-169,B:287-357 [30495]
        Other proteins in same PDB: d1feba3, d1febb3
        complexed with fad
      4. 2097282Domain d1febb2: 1feb B:170-286 [30496]
        Other proteins in same PDB: d1feba3, d1febb3
        complexed with fad
    3. Domains for 1fec:
      1. 2097275Domain d1feca1: 1fec A:1-169,A:287-357 [30489]
        Other proteins in same PDB: d1feca3, d1fecb3
        complexed with fad
      2. 2097276Domain d1feca2: 1fec A:170-286 [30490]
        Other proteins in same PDB: d1feca3, d1fecb3
        complexed with fad
      3. 2097277Domain d1fecb1: 1fec B:2-169,B:287-357 [30491]
        Other proteins in same PDB: d1feca3, d1fecb3
        complexed with fad
      4. 2097278Domain d1fecb2: 1fec B:170-286 [30492]
        Other proteins in same PDB: d1feca3, d1fecb3
        complexed with fad
    4. Domains for 1typ:
      1. 2097295Domain d1typa1: 1typ A:1-169,A:287-358 [30509]
        Other proteins in same PDB: d1typa3, d1typb3
        complexed with fad, gsh, nap
      2. 2097296Domain d1typa2: 1typ A:170-286 [30510]
        Other proteins in same PDB: d1typa3, d1typb3
        complexed with fad, gsh, nap
      3. 2097297Domain d1typb1: 1typ B:2-169,B:287-358 [30511]
        Other proteins in same PDB: d1typa3, d1typb3
        complexed with fad, gsh, nap
      4. 2097298Domain d1typb2: 1typ B:170-286 [30512]
        Other proteins in same PDB: d1typa3, d1typb3
        complexed with fad, gsh, nap
    5. Domains for 1tyt:
      1. 2097299Domain d1tyta1: 1tyt A:1-169,A:287-358 [30513]
        Other proteins in same PDB: d1tyta3, d1tytb3
        complexed with fad
      2. 2097300Domain d1tyta2: 1tyt A:170-286 [30514]
        Other proteins in same PDB: d1tyta3, d1tytb3
        complexed with fad
      3. 2097301Domain d1tytb1: 1tyt B:2-169,B:287-358 [30515]
        Other proteins in same PDB: d1tyta3, d1tytb3
        complexed with fad
      4. 2097302Domain d1tytb2: 1tyt B:170-286 [30516]
        Other proteins in same PDB: d1tyta3, d1tytb3
        complexed with fad
    6. Domains for 2tpr:
      1. 2097291Domain d2tpra1: 2tpr A:1-168,A:286-357 [30505]
        Other proteins in same PDB: d2tpra3, d2tprb3
        complexed with fad
      2. 2097292Domain d2tpra2: 2tpr A:169-285 [30506]
        Other proteins in same PDB: d2tpra3, d2tprb3
        complexed with fad
      3. 2097293Domain d2tprb1: 2tpr B:1-168,B:286-357 [30507]
        Other proteins in same PDB: d2tpra3, d2tprb3
        complexed with fad
      4. 2097294Domain d2tprb2: 2tpr B:169-285 [30508]
        Other proteins in same PDB: d2tpra3, d2tprb3
        complexed with fad
  2. 2097303Leishmania infantum [TaxId:5671] [267748] (1 PDB entry)
  3. 2097308Trypanosoma cruzi [TaxId:5693] [51949] (4 PDB entries)
    1. Domains for 1aog:
      1. 2097309Domain d1aoga1: 1aog A:3-169,A:287-357 [30517]
        Other proteins in same PDB: d1aoga3, d1aogb3
        complexed with fad, mae
      2. 2097310Domain d1aoga2: 1aog A:170-286 [30518]
        Other proteins in same PDB: d1aoga3, d1aogb3
        complexed with fad, mae
      3. 2097311Domain d1aogb1: 1aog B:5-169,B:287-357 [30519]
        Other proteins in same PDB: d1aoga3, d1aogb3
        complexed with fad, mae
      4. 2097312Domain d1aogb2: 1aog B:170-286 [30520]
        Other proteins in same PDB: d1aoga3, d1aogb3
        complexed with fad, mae
    2. Domains for 1bzl:
      1. 2097313Domain d1bzla1: 1bzl A:2-169,A:287-357 [30521]
        Other proteins in same PDB: d1bzla3, d1bzlb3
        complexed with fad, gcg
      2. 2097314Domain d1bzla2: 1bzl A:170-286 [30522]
        Other proteins in same PDB: d1bzla3, d1bzlb3
        complexed with fad, gcg
      3. 2097315Domain d1bzlb1: 1bzl B:5-169,B:287-357 [30523]
        Other proteins in same PDB: d1bzla3, d1bzlb3
        complexed with fad, gcg
      4. 2097316Domain d1bzlb2: 1bzl B:170-286 [30524]
        Other proteins in same PDB: d1bzla3, d1bzlb3
        complexed with fad, gcg
    3. Domains for 1gxf:
      1. 2097317Domain d1gxfa1: 1gxf A:4-169,A:287-357 [90527]
        Other proteins in same PDB: d1gxfa3, d1gxfb3
        complexed with fad, mae, qum
      2. 2097318Domain d1gxfa2: 1gxf A:170-286 [90528]
        Other proteins in same PDB: d1gxfa3, d1gxfb3
        complexed with fad, mae, qum
      3. 2097319Domain d1gxfb1: 1gxf B:5-169,B:287-357 [90530]
        Other proteins in same PDB: d1gxfa3, d1gxfb3
        complexed with fad, mae, qum
      4. 2097320Domain d1gxfb2: 1gxf B:170-286 [90531]
        Other proteins in same PDB: d1gxfa3, d1gxfb3
        complexed with fad, mae, qum
    4. Domains for 1nda:
      1. 2097321Domain d1ndaa1: 1nda A:4-169,A:287-357 [30525]
        Other proteins in same PDB: d1ndaa3, d1ndab3, d1ndac3, d1ndad3
        complexed with fad
      2. 2097322Domain d1ndaa2: 1nda A:170-286 [30526]
        Other proteins in same PDB: d1ndaa3, d1ndab3, d1ndac3, d1ndad3
        complexed with fad
      3. 2097323Domain d1ndab1: 1nda B:4-169,B:287-357 [30527]
        Other proteins in same PDB: d1ndaa3, d1ndab3, d1ndac3, d1ndad3
        complexed with fad
      4. 2097324Domain d1ndab2: 1nda B:170-286 [30528]
        Other proteins in same PDB: d1ndaa3, d1ndab3, d1ndac3, d1ndad3
        complexed with fad
      5. 2097325Domain d1ndac1: 1nda C:170-286 [118564]
        Other proteins in same PDB: d1ndaa3, d1ndab3, d1ndac3, d1ndad3
        duplicate of 1NDA A:170-286
        complexed with fad
      6. 2097326Domain d1ndac2: 1nda C:4-169,C:287-357 [118565]
        Other proteins in same PDB: d1ndaa3, d1ndab3, d1ndac3, d1ndad3
        duplicate of 1NDA A:4-169,A:287-357
        complexed with fad
      7. 2097327Domain d1ndad1: 1nda D:170-286 [118567]
        Other proteins in same PDB: d1ndaa3, d1ndab3, d1ndac3, d1ndad3
        duplicate of 1NDA A:170-286
        complexed with fad
      8. 2097328Domain d1ndad2: 1nda D:4-169,D:287-357 [118568]
        Other proteins in same PDB: d1ndaa3, d1ndab3, d1ndac3, d1ndad3
        duplicate of 1NDA A:4-169,A:287-357
        complexed with fad

More info for Protein Trypanothione reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains

Timeline for Protein Trypanothione reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains: