SCOPe 2.07: Species: Human (Homo sapiens) [TaxId: 9606]

Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

Root: SCOPe 2.07
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander
Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (9 families)

Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (15 proteins)
duplication: both domains have similar folds and functions
most members of the family contain common C-terminal alpha+beta domain

Protein Glutathione reductase [51944] (3 species)
Species Human (Homo sapiens) [TaxId:9606] [51945] (23 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

Domain(s) for 1bwc:
1. Domain d1bwca1: 1bwc A:18-165,A:291-363 [30459]
  Other proteins in same PDB: d1bwca3
  complexed with aj3, cl, fad
2. Domain d1bwca2: 1bwc A:166-290 [30460]
  Other proteins in same PDB: d1bwca3
  complexed with aj3, cl, fad
Domain(s) for 1dnc:
1. Domain d1dnca1: 1dnc A:18-165,A:291-363 [30443]
  Other proteins in same PDB: d1dnca3
  complexed with fad, gsh, po4
2. Domain d1dnca2: 1dnc A:166-290 [30444]
  Other proteins in same PDB: d1dnca3
  complexed with fad, gsh, po4
Domain(s) for 1gra:
1. Domain d1graa1: 1gra A:18-165,A:291-363 [30451]
  Other proteins in same PDB: d1graa3
  complexed with fad, gsh, ndp
2. Domain d1graa2: 1gra A:166-290 [30452]
  Other proteins in same PDB: d1graa3
  complexed with fad, gsh, ndp
Domain(s) for 1grb:
1. Domain d1grba1: 1grb A:18-165,A:291-363 [30447]
  Other proteins in same PDB: d1grba3
  complexed with fad, nad, po4
2. Domain d1grba2: 1grb A:166-290 [30448]
  Other proteins in same PDB: d1grba3
  complexed with fad, nad, po4
Domain(s) for 1gre:
1. Domain d1grea1: 1gre A:18-165,A:291-363 [30453]
  Other proteins in same PDB: d1grea3
  complexed with fad, gsh, po4
2. Domain d1grea2: 1gre A:166-290 [30454]
  Other proteins in same PDB: d1grea3
  complexed with fad, gsh, po4
Domain(s) for 1grf:
1. Domain d1grfa1: 1grf A:18-165,A:291-363 [30457]
  Other proteins in same PDB: d1grfa3
  complexed with acm, fad, po4
2. Domain d1grfa2: 1grf A:166-290 [30458]
  Other proteins in same PDB: d1grfa3
  complexed with acm, fad, po4
Domain(s) for 1grg:
1. Domain d1grga1: 1grg A:18-165,A:291-363 [30455]
  Other proteins in same PDB: d1grga3
  complexed with fad, po4
2. Domain d1grga2: 1grg A:166-290 [30456]
  Other proteins in same PDB: d1grga3
  complexed with fad, po4
Domain(s) for 1grt:
1. Domain d1grta1: 1grt A:17-165,A:291-363 [30467]
  Other proteins in same PDB: d1grta3
  complexed with fad; mutant
2. Domain d1grta2: 1grt A:166-290 [30468]
  Other proteins in same PDB: d1grta3
  complexed with fad; mutant
Domain(s) for 1gsn:
1. Domain d1gsna1: 1gsn A:18-165,A:291-363 [30445]
  Other proteins in same PDB: d1gsna3
  complexed with fad, gsh, po4
2. Domain d1gsna2: 1gsn A:166-290 [30446]
  Other proteins in same PDB: d1gsna3
  complexed with fad, gsh, po4
Domain(s) for 1k4q:
1. Domain d1k4qa1: 1k4q A:18-165,A:291-363 [68140]
  Other proteins in same PDB: d1k4qa3
  complexed with fad
2. Domain d1k4qa2: 1k4q A:166-290 [68141]
  Other proteins in same PDB: d1k4qa3
  complexed with fad
Domain(s) for 1xan:
1. Domain d1xana1: 1xan A:18-165,A:291-363 [30449]
  Other proteins in same PDB: d1xana3
  complexed with fad, hxp
2. Domain d1xana2: 1xan A:166-290 [30450]
  Other proteins in same PDB: d1xana3
  complexed with fad, hxp
Domain(s) for 2gh5:
1. Domain d2gh5a1: 2gh5 A:18-165,A:291-363 [204363]
  Other proteins in same PDB: d2gh5a3, d2gh5b3
  automated match to d3grsa1
  complexed with eli, fad, gol, po4
2. Domain d2gh5a2: 2gh5 A:166-290 [204364]
  Other proteins in same PDB: d2gh5a3, d2gh5b3
  automated match to d3grsa2
  complexed with eli, fad, gol, po4
3. Domain d2gh5b1: 2gh5 B:18-165,B:291-363 [204366]
  Other proteins in same PDB: d2gh5a3, d2gh5b3
  automated match to d3grsa1
  complexed with eli, fad, gol, po4
4. Domain d2gh5b2: 2gh5 B:166-290 [204367]
  Other proteins in same PDB: d2gh5a3, d2gh5b3
  automated match to d3grsa2
  complexed with eli, fad, gol, po4
Domain(s) for 2grt:
1. Domain d2grta1: 2grt A:18-165,A:291-363 [30469]
  Other proteins in same PDB: d2grta3
  complexed with fad, gds; mutant
2. Domain d2grta2: 2grt A:166-290 [30470]
  Other proteins in same PDB: d2grta3
  complexed with fad, gds; mutant
Domain(s) for 3djj:
1. Domain d3djja1: 3djj A:17-165,A:291-363 [209206]
  Other proteins in same PDB: d3djja3
  automated match to d3grsa1
  complexed with fad, gol, ndp, po4, so4
2. Domain d3djja2: 3djj A:166-290 [209207]
  Other proteins in same PDB: d3djja3
  automated match to d3grsa2
  complexed with fad, gol, ndp, po4, so4
Domain(s) for 3dk4:
1. Domain d3dk4a1: 3dk4 A:17-165,A:291-363 [209209]
  Other proteins in same PDB: d3dk4a3
  automated match to d3grsa1
  complexed with fad, gsh, ndp, so4
2. Domain d3dk4a2: 3dk4 A:166-290 [209210]
  Other proteins in same PDB: d3dk4a3
  automated match to d3grsa2
  complexed with fad, gsh, ndp, so4
Domain(s) for 3dk8:
1. Domain d3dk8a1: 3dk8 A:17-165,A:291-363 [209214]
  Other proteins in same PDB: d3dk8a3
  automated match to d3grsa1
  complexed with fad, gol, gsh, so4
2. Domain d3dk8a2: 3dk8 A:166-290 [209215]
  Other proteins in same PDB: d3dk8a3
  automated match to d3grsa2
  complexed with fad, gol, gsh, so4
Domain(s) for 3dk9:
1. Domain d3dk9a1: 3dk9 A:17-165,A:291-363 [209217]
  Other proteins in same PDB: d3dk9a3
  automated match to d3grsa1
  complexed with fad, so4
2. Domain d3dk9a2: 3dk9 A:166-290 [209218]
  Other proteins in same PDB: d3dk9a3
  automated match to d3grsa2
  complexed with fad, so4
Domain(s) for 3grs:
1. Domain d3grsa1: 3grs A:18-165,A:291-363 [30441]
  Other proteins in same PDB: d3grsa3
  complexed with fad, po4
2. Domain d3grsa2: 3grs A:166-290 [30442]
  Other proteins in same PDB: d3grsa3
  complexed with fad, po4
Domain(s) for 3grt:
1. Domain d3grta1: 3grt A:18-165,A:291-363 [30463]
  Other proteins in same PDB: d3grta3
  complexed with fad, ts2; mutant
2. Domain d3grta2: 3grt A:166-290 [30464]
  Other proteins in same PDB: d3grta3
  complexed with fad, ts2; mutant
Domain(s) for 3sqp:
1. Domain d3sqpa1: 3sqp A:18-165,A:291-363 [261745]
  Other proteins in same PDB: d3sqpa3, d3sqpb3
  automated match to d3grsa1
  protein/RNA complex; complexed with 3j8, fad, gol, so4
2. Domain d3sqpa2: 3sqp A:166-290 [261746]
  Other proteins in same PDB: d3sqpa3, d3sqpb3
  automated match to d3grsa2
  protein/RNA complex; complexed with 3j8, fad, gol, so4
3. Domain d3sqpb1: 3sqp B:18-165,B:291-363 [261599]
  Other proteins in same PDB: d3sqpa3, d3sqpb3
  automated match to d3grsa1
  protein/RNA complex; complexed with 3j8, fad, gol, so4
4. Domain d3sqpb2: 3sqp B:166-290 [261600]
  Other proteins in same PDB: d3sqpa3, d3sqpb3
  automated match to d3grsa2
  protein/RNA complex; complexed with 3j8, fad, gol, so4
Domain(s) for 4gr1:
1. Domain d4gr1a1: 4gr1 A:18-165,A:291-363 [30461]
  Other proteins in same PDB: d4gr1a3
  complexed with fad, po4, rgs
2. Domain d4gr1a2: 4gr1 A:166-290 [30462]
  Other proteins in same PDB: d4gr1a3
  complexed with fad, po4, rgs
Domain(s) for 4grt:
1. Domain d4grta1: 4grt A:18-165,A:291-363 [30471]
  Other proteins in same PDB: d4grta3
  complexed with fad, gcg; mutant
2. Domain d4grta2: 4grt A:166-290 [30472]
  Other proteins in same PDB: d4grta3
  complexed with fad, gcg; mutant
Domain(s) for 5grt:
1. Domain d5grta1: 5grt A:18-165,A:291-363 [30465]
  Other proteins in same PDB: d5grta3
  complexed with fad, ts4; mutant
2. Domain d5grta2: 5grt A:166-290 [30466]
  Other proteins in same PDB: d5grta3
  complexed with fad, ts4; mutant

More info for Species Human (Homo sapiens) [TaxId:9606] from c.3.1.5 Glutathione reductase

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.3.1.5 Glutathione reductase:

Species Human (Homo sapiens) [TaxId:9606] from c.3.1.5 Glutathione reductase first appeared (with stable ids) in SCOP 1.55
Species Human (Homo sapiens) [TaxId:9606] from c.3.1.5 Glutathione reductase appears in SCOPe 2.06
Species Human (Homo sapiens) [TaxId:9606] from c.3.1.5 Glutathione reductase does not appear in SCOPe 2.08