Lineage for Protein: Glutathione reductase

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2096453Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
    core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander
  4. 2096454Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (9 families) (S)
  5. 2096984Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (15 protein domains)
    duplication: both domains have similar folds and functions
    most members of the family contain common C-terminal alpha+beta domain
  6. 2097072Protein Glutathione reductase [51944] (3 species)

Species:

  1. 2097073Escherichia coli [TaxId:562] [51946] (4 PDB entries)
    1. Domains for 1ger:
      1. 2097078Domain d1gera1: 1ger A:3-146,A:263-335 [30477]
        Other proteins in same PDB: d1gera3, d1gerb3
        complexed with fad
      2. 2097079Domain d1gera2: 1ger A:147-262 [30478]
        Other proteins in same PDB: d1gera3, d1gerb3
        complexed with fad
      3. 2097080Domain d1gerb1: 1ger B:2-146,B:263-335 [30479]
        Other proteins in same PDB: d1gera3, d1gerb3
        complexed with fad
      4. 2097081Domain d1gerb2: 1ger B:147-262 [30480]
        Other proteins in same PDB: d1gera3, d1gerb3
        complexed with fad
    2. Domains for 1ges:
      1. 2097074Domain d1gesa1: 1ges A:3-146,A:263-335 [30473]
        Other proteins in same PDB: d1gesa3, d1gesb3
        complexed with fad
      2. 2097075Domain d1gesa2: 1ges A:147-262 [30474]
        Other proteins in same PDB: d1gesa3, d1gesb3
        complexed with fad
      3. 2097076Domain d1gesb1: 1ges B:2-146,B:263-335 [30475]
        Other proteins in same PDB: d1gesa3, d1gesb3
        complexed with fad
      4. 2097077Domain d1gesb2: 1ges B:147-262 [30476]
        Other proteins in same PDB: d1gesa3, d1gesb3
        complexed with fad
    3. Domains for 1get:
      1. 2097082Domain d1geta1: 1get A:3-146,A:263-335 [30481]
        Other proteins in same PDB: d1geta3, d1getb3
        complexed with fad, nap
      2. 2097083Domain d1geta2: 1get A:147-262 [30482]
        Other proteins in same PDB: d1geta3, d1getb3
        complexed with fad, nap
      3. 2097084Domain d1getb1: 1get B:2-146,B:263-335 [30483]
        Other proteins in same PDB: d1geta3, d1getb3
        complexed with fad, nap
      4. 2097085Domain d1getb2: 1get B:147-262 [30484]
        Other proteins in same PDB: d1geta3, d1getb3
        complexed with fad, nap
    4. Domains for 1geu:
      1. 2097086Domain d1geua1: 1geu A:3-146,A:263-335 [30485]
        Other proteins in same PDB: d1geua3, d1geub3
        complexed with fad, nad
      2. 2097087Domain d1geua2: 1geu A:147-262 [30486]
        Other proteins in same PDB: d1geua3, d1geub3
        complexed with fad, nad
      3. 2097088Domain d1geub1: 1geu B:2-146,B:263-335 [30487]
        Other proteins in same PDB: d1geua3, d1geub3
        complexed with fad, nad
      4. 2097089Domain d1geub2: 1geu B:147-262 [30488]
        Other proteins in same PDB: d1geua3, d1geub3
        complexed with fad, nad
  2. 2097090Human (Homo sapiens) [TaxId:9606] [51945] (23 PDB entries)
    1. Domains for 1bwc:
      1. 2097123Domain d1bwca1: 1bwc A:18-165,A:291-363 [30459]
        Other proteins in same PDB: d1bwca3
        complexed with aj3, cl, fad
      2. 2097124Domain d1bwca2: 1bwc A:166-290 [30460]
        Other proteins in same PDB: d1bwca3
        complexed with aj3, cl, fad
    2. Domains for 1dnc:
      1. 2097101Domain d1dnca1: 1dnc A:18-165,A:291-363 [30443]
        Other proteins in same PDB: d1dnca3
        complexed with fad, gsh, po4
      2. 2097102Domain d1dnca2: 1dnc A:166-290 [30444]
        Other proteins in same PDB: d1dnca3
        complexed with fad, gsh, po4
    3. Domains for 1gra:
      1. 2097117Domain d1graa1: 1gra A:18-165,A:291-363 [30451]
        Other proteins in same PDB: d1graa3
        complexed with fad, gsh, ndp
      2. 2097118Domain d1graa2: 1gra A:166-290 [30452]
        Other proteins in same PDB: d1graa3
        complexed with fad, gsh, ndp
    4. Domains for 1grb:
      1. 2097109Domain d1grba1: 1grb A:18-165,A:291-363 [30447]
        Other proteins in same PDB: d1grba3
        complexed with fad, nad, po4
      2. 2097110Domain d1grba2: 1grb A:166-290 [30448]
        Other proteins in same PDB: d1grba3
        complexed with fad, nad, po4
    5. Domains for 1gre:
      1. 2097115Domain d1grea1: 1gre A:18-165,A:291-363 [30453]
        Other proteins in same PDB: d1grea3
        complexed with fad, gsh, po4
      2. 2097116Domain d1grea2: 1gre A:166-290 [30454]
        Other proteins in same PDB: d1grea3
        complexed with fad, gsh, po4
    6. Domains for 1grf:
      1. 2097119Domain d1grfa1: 1grf A:18-165,A:291-363 [30457]
        Other proteins in same PDB: d1grfa3
        complexed with acm, fad, po4
      2. 2097120Domain d1grfa2: 1grf A:166-290 [30458]
        Other proteins in same PDB: d1grfa3
        complexed with acm, fad, po4
    7. Domains for 1grg:
      1. 2097121Domain d1grga1: 1grg A:18-165,A:291-363 [30455]
        Other proteins in same PDB: d1grga3
        complexed with fad, po4
      2. 2097122Domain d1grga2: 1grg A:166-290 [30456]
        Other proteins in same PDB: d1grga3
        complexed with fad, po4
    8. Domains for 1grt:
      1. 2097131Domain d1grta1: 1grt A:17-165,A:291-363 [30467]
        Other proteins in same PDB: d1grta3
        complexed with fad; mutant
      2. 2097132Domain d1grta2: 1grt A:166-290 [30468]
        Other proteins in same PDB: d1grta3
        complexed with fad; mutant
    9. Domains for 1gsn:
      1. 2097103Domain d1gsna1: 1gsn A:18-165,A:291-363 [30445]
        Other proteins in same PDB: d1gsna3
        complexed with fad, gsh, po4
      2. 2097104Domain d1gsna2: 1gsn A:166-290 [30446]
        Other proteins in same PDB: d1gsna3
        complexed with fad, gsh, po4
    10. Domains for 1k4q:
      1. 2097113Domain d1k4qa1: 1k4q A:18-165,A:291-363 [68140]
        Other proteins in same PDB: d1k4qa3
        complexed with fad
      2. 2097114Domain d1k4qa2: 1k4q A:166-290 [68141]
        Other proteins in same PDB: d1k4qa3
        complexed with fad
    11. Domains for 1xan:
      1. 2097111Domain d1xana1: 1xan A:18-165,A:291-363 [30449]
        Other proteins in same PDB: d1xana3
        complexed with fad, hxp
      2. 2097112Domain d1xana2: 1xan A:166-290 [30450]
        Other proteins in same PDB: d1xana3
        complexed with fad, hxp
    12. Domains for 2gh5:
      1. 2097105Domain d2gh5a1: 2gh5 A:18-165,A:291-363 [204363]
        Other proteins in same PDB: d2gh5a3, d2gh5b3
        automated match to d3grsa1
        complexed with eli, fad, gol, po4
      2. 2097106Domain d2gh5a2: 2gh5 A:166-290 [204364]
        Other proteins in same PDB: d2gh5a3, d2gh5b3
        automated match to d3grsa2
        complexed with eli, fad, gol, po4
      3. 2097107Domain d2gh5b1: 2gh5 B:18-165,B:291-363 [204366]
        Other proteins in same PDB: d2gh5a3, d2gh5b3
        automated match to d3grsa1
        complexed with eli, fad, gol, po4
      4. 2097108Domain d2gh5b2: 2gh5 B:166-290 [204367]
        Other proteins in same PDB: d2gh5a3, d2gh5b3
        automated match to d3grsa2
        complexed with eli, fad, gol, po4
    13. Domains for 2grt:
      1. 2097137Domain d2grta1: 2grt A:18-165,A:291-363 [30469]
        Other proteins in same PDB: d2grta3
        complexed with fad, gds; mutant
      2. 2097138Domain d2grta2: 2grt A:166-290 [30470]
        Other proteins in same PDB: d2grta3
        complexed with fad, gds; mutant
    14. Domains for 3djj:
      1. 2097093Domain d3djja1: 3djj A:17-165,A:291-363 [209206]
        Other proteins in same PDB: d3djja3
        automated match to d3grsa1
        complexed with fad, gol, ndp, po4, so4
      2. 2097094Domain d3djja2: 3djj A:166-290 [209207]
        Other proteins in same PDB: d3djja3
        automated match to d3grsa2
        complexed with fad, gol, ndp, po4, so4
    15. Domains for 3dk4:
      1. 2097097Domain d3dk4a1: 3dk4 A:17-165,A:291-363 [209209]
        Other proteins in same PDB: d3dk4a3
        automated match to d3grsa1
        complexed with fad, gsh, ndp, so4
      2. 2097098Domain d3dk4a2: 3dk4 A:166-290 [209210]
        Other proteins in same PDB: d3dk4a3
        automated match to d3grsa2
        complexed with fad, gsh, ndp, so4
    16. Domains for 3dk8:
      1. 2097095Domain d3dk8a1: 3dk8 A:17-165,A:291-363 [209214]
        Other proteins in same PDB: d3dk8a3
        automated match to d3grsa1
        complexed with fad, gol, gsh, so4
      2. 2097096Domain d3dk8a2: 3dk8 A:166-290 [209215]
        Other proteins in same PDB: d3dk8a3
        automated match to d3grsa2
        complexed with fad, gol, gsh, so4
    17. Domains for 3dk9:
      1. 2097091Domain d3dk9a1: 3dk9 A:17-165,A:291-363 [209217]
        Other proteins in same PDB: d3dk9a3
        automated match to d3grsa1
        complexed with fad, so4
      2. 2097092Domain d3dk9a2: 3dk9 A:166-290 [209218]
        Other proteins in same PDB: d3dk9a3
        automated match to d3grsa2
        complexed with fad, so4
    18. Domains for 3grs:
      1. 2097099Domain d3grsa1: 3grs A:18-165,A:291-363 [30441]
        Other proteins in same PDB: d3grsa3
        complexed with fad, po4
      2. 2097100Domain d3grsa2: 3grs A:166-290 [30442]
        Other proteins in same PDB: d3grsa3
        complexed with fad, po4
    19. Domains for 3grt:
      1. 2097133Domain d3grta1: 3grt A:18-165,A:291-363 [30463]
        Other proteins in same PDB: d3grta3
        complexed with fad, ts2; mutant
      2. 2097134Domain d3grta2: 3grt A:166-290 [30464]
        Other proteins in same PDB: d3grta3
        complexed with fad, ts2; mutant
    20. Domains for 3sqp:
      1. 2097127Domain d3sqpa1: 3sqp A:18-165,A:291-363 [261745]
        Other proteins in same PDB: d3sqpa3, d3sqpb3
        automated match to d3grsa1
        protein/RNA complex; complexed with 3j8, fad, gol, so4
      2. 2097128Domain d3sqpa2: 3sqp A:166-290 [261746]
        Other proteins in same PDB: d3sqpa3, d3sqpb3
        automated match to d3grsa2
        protein/RNA complex; complexed with 3j8, fad, gol, so4
      3. 2097129Domain d3sqpb1: 3sqp B:18-165,B:291-363 [261599]
        Other proteins in same PDB: d3sqpa3, d3sqpb3
        automated match to d3grsa1
        protein/RNA complex; complexed with 3j8, fad, gol, so4
      4. 2097130Domain d3sqpb2: 3sqp B:166-290 [261600]
        Other proteins in same PDB: d3sqpa3, d3sqpb3
        automated match to d3grsa2
        protein/RNA complex; complexed with 3j8, fad, gol, so4
    21. Domains for 4gr1:
      1. 2097125Domain d4gr1a1: 4gr1 A:18-165,A:291-363 [30461]
        Other proteins in same PDB: d4gr1a3
        complexed with fad, po4, rgs
      2. 2097126Domain d4gr1a2: 4gr1 A:166-290 [30462]
        Other proteins in same PDB: d4gr1a3
        complexed with fad, po4, rgs
    22. Domains for 4grt:
      1. 2097139Domain d4grta1: 4grt A:18-165,A:291-363 [30471]
        Other proteins in same PDB: d4grta3
        complexed with fad, gcg; mutant
      2. 2097140Domain d4grta2: 4grt A:166-290 [30472]
        Other proteins in same PDB: d4grta3
        complexed with fad, gcg; mutant
    23. Domains for 5grt:
      1. 2097135Domain d5grta1: 5grt A:18-165,A:291-363 [30465]
        Other proteins in same PDB: d5grta3
        complexed with fad, ts4; mutant
      2. 2097136Domain d5grta2: 5grt A:166-290 [30466]
        Other proteins in same PDB: d5grta3
        complexed with fad, ts4; mutant
  3. 2097141Malaria parasite (Plasmodium falciparum) [TaxId:5833] [89548] (1 PDB entry)

More info for Protein Glutathione reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains

Timeline for Protein Glutathione reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains: