SCOPe 2.02: Family c.3.1.2: FAD-linked reductases, N-terminal domain

Lineage for Family c.3.1.2: FAD-linked reductases, N-terminal domain

1. Root: SCOPe 2.02

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
   core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander

4. Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (8 families)

5. Family c.3.1.2: FAD-linked reductases, N-terminal domain [51913] (18 proteins)
   C-terminal domain is alpha+beta is common for the family

Proteins:

1. Cholesterol oxidase of GMC family [51914] (3 species)

   1. Species Brevibacterium sterolicum [TaxId:1702] [51915] (2 PDB entries)

   2. Species Streptomyces sp. (strain SA-COO) (Streptomyces sp. SA-COO) [TaxId:74576] [159428] (1 PDB entry)

   3. Species Streptomyces sp. [TaxId:1931] [51916] (13 PDB entries)

2. Dihydroxypyridine hydroxylase DhpH [159430] (1 species)

   • Species Arthrobacter nicotinovorans [TaxId:29320] [159431] (1 PDB entry)
     Uniprot Q93NG3 2-163,292-394

3. Electron transfer flavoprotein-ubiquinone oxidoreductase, EFT-QO [141940] (1 species)

   • Species Pig (Sus scrofa) [TaxId:9823] [141941] (2 PDB entries)
     Uniprot P55931 27-259,359-505

4. Flavoprotein domain of flavocytochrome cellobiose dehydrogenase (CDH), FAD-binding domain [82309] (1 species)

   • Species Basidomycetes fungus (Phanerochaete chrysosporium) [TaxId:5306] [82310] (2 PDB entries)

5. Glucose oxidase [51924] (2 species)

   1. Species Aspergillus niger [TaxId:5061] [51925] (2 PDB entries)

   2. Species Penicillium amagasakiense [TaxId:63559] [51926] (1 PDB entry)

6. Glycine oxidase ThiO [89544] (1 species)

   • Species Bacillus sp. [TaxId:1409] [89545] (3 PDB entries)

7. Hydroxynitrile lyase [82307] (1 species)

   • Species Almond (Prunus dulcis) [TaxId:3755] [82308] (1 PDB entry)

8. L-aminoacid oxidase [51929] (2 species)

   1. Species Halys viper (Agkistrodon halys) [TaxId:8714] [102179] (4 PDB entries)
      Uniprot Q90W54 21-504

   2. Species Malayan pit viper (Calloselasma rhodostoma) [TaxId:8717] [51930] (3 PDB entries)

9. Lysine-specific histone demethylase 1, LSD1 [159432] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [159433] (8 PDB entries)
     Uniprot O60341 274-654,764-836

10. Monoamine oxidase B [69423] (2 species)

    1. Species Human (Homo sapiens) [TaxId:9606] [69424] (28 PDB entries)

    2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [102180] (1 PDB entry)

11. Monooxygenase PhzS [159434] (1 species)

    • Species Pseudomonas aeruginosa [TaxId:287] [159435] (1 PDB entry)
      Uniprot Q9HWG9 4-182,294-402

12. N,N-dimethylglycine oxidase [102181] (1 species)

    • Species Arthrobacter globiformis [TaxId:1665] [102182] (3 PDB entries)

13. p-Hydroxybenzoate hydroxylase, PHBH [51917] (2 species)

    1. Species Pseudomonas aeruginosa [TaxId:287] [51919] (18 PDB entries)

    2. Species Pseudomonas fluorescens [TaxId:294] [51918] (17 PDB entries)

14. Phenol hydroxylase [51922] (1 species)
    structurally very similar to PHBH, but contains additional C-terminal domain of the thioredoxin-like fold

    • Species Soil-living yeast (Trichosporon cutaneum) [TaxId:5554] [51923] (2 PDB entries)

15. Polyamine oxidase [51927] (1 species)

    • Species Maize (Zea mays) [TaxId:4577] [51928] (7 PDB entries)

16. Protoporphyrinogen oxidase [102183] (2 species)

    1. Species Myxococcus xanthus [TaxId:34] [159429] (2 PDB entries)
       Uniprot P56601 10-306,415-464

    2. Species Tobacco (Nicotiana tabacum) [TaxId:4097] [102184] (1 PDB entry)

17. Pyranose 2-oxidase [117439] (1 species)

    • Species White-rot fungus (Peniophora sp. SG) [TaxId:204723] [117440] (5 PDB entries)
      Uniprot Q8J136 43-619

18. Sarcosine oxidase [51920] (1 species)

    • Species Bacillus sp., strain b0618 [TaxId:1409] [51921] (13 PDB entries)

More info for Family c.3.1.2: FAD-linked reductases, N-terminal domain

Timeline for Family c.3.1.2: FAD-linked reductases, N-terminal domain:

• Family c.3.1.2: FAD-linked reductases, N-terminal domain first appeared (with stable ids) in SCOP 1.55
  
• Family c.3.1.2: FAD-linked reductases, N-terminal domain appears in SCOPe 2.01
  
• Family c.3.1.2: FAD-linked reductases, N-terminal domain appears in SCOPe 2.03
  
• Family c.3.1.2: FAD-linked reductases, N-terminal domain appears in the current release, SCOPe 2.08